One-Week Italy Self-Drive Road Trip With Itinerary from Pisa traveling west to Genoa and Milan

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Aerial view at tower of Pisa in Italy on a sunny day.
Tourist female in Pisa, Arno river, lamp and buildings reflection. Lungarno view.santa maria della spina
One-Week Italy Self-Drive Road Trip With Itinerary from Pisa traveling west to Genoa and Milan
One-Week Italy Self-Drive Road Trip With Itinerary from Pisa traveling west to Genoa and Milan
One-Week Italy Self-Drive Road Trip With Itinerary from Pisa traveling west to Genoa and Milan
One-Week Italy Self-Drive Road Trip With Itinerary from Pisa traveling west to Genoa and Milan
One-Week Italy Self-Drive Road Trip With Itinerary from Pisa traveling west to Genoa and Milan
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Experience the freedom of the open road on an unforgettable 8-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Pisa, Tirrenia, Corniglia, Genoa, Milan, and Priorato.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Pisa, 1 night in Genoa, and 3 nights in Milan. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Pisa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Duomo Di Milano Museum and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Pisa, Tirrenia, Corniglia, Genoa, Milan, and Priorato, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Pisa - Arrival day
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  • Knights' Square
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Welcome to Pisa, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Pisa before embarking on the next leg of your journey.

Pisa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Knights' Square. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Pisa. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pisa, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Anima di Grano Pizzeria Napoletana Pisa Italy, an excellent option for tonight's dining. Looking for something different? il Mercante offers a tantalizing alternative with its diverse menu. And don’t miss La Ghiotteria. Known for great service, it’s a fantastic choice for tonight in Pisa.

Explore the vibrant nightlife at Jeffer Cocktails & Friends after your meal, a hub for lively evenings and memorable moments. Or, head to Le Parisien Wine Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Las Volta Cocktailbar is perfect for those looking to extend their night with a touch of local flavor.

Raise a toast to the start of your 8-day road trip in Italy!

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Day2

Day 2

  • Pisa
  • Tirrenia
  • More

Drive 44 km, 1 hour 20 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Bagno degli Americani
  • Parco Regionale Migliarino, San Rossore, Massaciuccoli
  • More

On day 2 of your road trip, you'll get the chance to experience Pisa, Tirrenia, and Cascine Vecchie. At the end of the day, you'll drive back to Pisa, where you still have 1 night left to stay.

No visit to Pisa is complete without Leaning Tower Of Pisa. This wondrous monument is one of the top attractions in the city. Proceed to Piazza Del Duomo, Pisa, another must-visit attraction.

As you wander through the inviting streets of Pisa, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Pisa Cathedral. This often recommended church is a traveler-favorite.

Set your GPS to Tirrenia and hit the road. Expect a journey of approximately 22 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Tirrenia beckons with new experiences!

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Bagno Degli Americani, a curiosity-inducing point of interest that everyone visiting Tirrenia should see.

Cascine Vecchie’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Tirrenia behind. This drive usually takes around 25 min. Cascine Vecchie welcomes you with a multitude of unique vacation experiences.

One of our top recommendations for your sightseeing is Parco Regionale Migliarino, San Rossore, Massaciuccoli. Spend some time admiring the eye-catching features of the nature reserve before you continue to your next stop.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Pisa.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Pisa. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at Ristorante Capodimonte Pisa, an iconic dining spot in Pisa. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Locanda Dei Pisani Doc Pisa, a popular restaurant in Pisa. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Baribaldi Pisa, a hidden gem nestled in Pisa. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like Bar Mocambo, known for its lively atmosphere. Tree is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Chupiteria offers an excellent atmosphere for those looking to amp up the evening.

Celebrate another amazing day of your road trip adventure in Italy!

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Day3

Day 3

  • Pisa
  • Corniglia
  • Genoa
  • More

Drive 212 km, 3 hours 35 min

  • Palazzo Blu
  • Santa Maria della Spina
  • Cittadella Nuova
  • Cinque Terre National Park
  • More

Your itinerary for day 3 of your road trip in Italy includes 2 stops and features some of the highlights of Pisa and Corniglia. At the end of the day, enjoy the comforts of a top-rated hotel in Genoa, where you'll spend 1 night.

Awaiting your discovery is the curiosity-inducing Palazzo Blu, a photogenic art gallery in Pisa. Next, go to Santa Maria Della Spina.

After visiting Palazzo Blu and Santa Maria Della Spina, have a stroll along Pisa's streets and take in the local charm. Continue your sightseeing by heading to Cittadella Nuova. This awe-inspiring park offers a unique experience.

Corniglia’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Pisa behind. This drive usually takes around 1 hour 34 min. Corniglia welcomes you with a multitude of unique vacation experiences.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Cinque Terre National Park, a locally renowned national park that everyone visiting Corniglia should see.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Have a memorable dining experience in Genoa by booking a table at San Giorgio, a 1-star Michelin restaurant presenting an exceptional modern and ligurian menu. For a different culinary experience in Genoa, The Cook shines as one of the top destinations, known for its delicious modern cuisine. This 1-star Michelin-awardee consistently earns high praises, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Il Marin is known as a top local spot in Genoa for its delicious seafood and contemporary cuisine. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

Let the evening flow smoothly from dinner to drinks at Scurreria Beer & Bagel, a top-rated bar in the area. For other recommendations, La Lepre provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Pisacane Iii offers a memorable night with diverse drink options and excellent service.

Relax and look forward to more memorable moments to come!

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Day4

Day 4

  • Genoa
  • Milan
  • More

Drive 144 km, 2 hours 17 min

  • piazza De Ferrari
  • Genoa Cathedral
  • Aquarium of Genoa
  • porto antico
  • More

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Genoa. At the end of the day, you’ll unwind at one of the finest accommodations in Milan, where you'll spend 3 nights.

Piazza De Ferrari is must-visit public square and a great option for a daytime tour of the area. Continue your journey to Genoa Cathedral, a curiosity-inducing church, located just a leisurely stroll away. Next, head to Aquarium Of Genoa, a mesmerizing aquarium, also available for your discovery today.

When you’re done exploring for the day, you’ll drive to your hotel in Milan. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Milan. Enjoy a relaxing evening as you savor delicious local cuisine.

Experience a taste of local culinary excellence while in Milan by securing a table at Enrico Bartolini al Mudec. An esteemed 3-star Michelin restaurant, it features an exceptional creative menu. For an alternative taste experience, visit Seta by Antonio Guida, famous for its scrumptious international and contemporary dishes. This 2-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Il Luogo Aimo e Nadia, a local favorite celebrated for its exquisite italian contemporary and modern cuisine in Milan. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for italian contemporary and modern cuisine lovers seeking top-notch culinary experiences.

Extend your evening after a delightful meal by visiting Nottingham Forest, which offers the perfect atmosphere for a night out. Moreover, Armani/bamboo Bar is another popular option for a drink or two. Likewise, Mag Cafe also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day5

Day 5

  • Milan
  • More

Drive 9 km, 1 hour

  • Leonardo da Vinci Museum of Science and Technology
  • Santa Maria delle Grazie Church
  • Castello Sforzesco
  • Sempione Park
  • Arch of Peace
  • More

Day 5 of your road trip across Italy promises a magnificent time exploring what to see in Milan. You have 2 nights left in Milan. Take the opportunity to experience more of the best attractions and activities in the city.

Museo Della Scienza E Della Tecnologia "leonardo Da Vinci" leaves a lasting impression. This museum is one of the most well-known places to visit in Milan. Next, head to Santa Maria Delle Grazie Church, a well-known church, known for its photogenic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Sforzesco Castle Art Library. This picture-perfect castle is a highly recommended experience. Nearby, you'll also find Parco Sempione and Arch Of Peace Visit these for an interesting touch to your journey.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Milan. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a wonderful meal at Dessert Bar Milano, a top-rated dining spot in Milan. If you're in the mood for something new, try Radisson Blu Hotel Milan, another premier location with a delectable menu. You might also want to book a table at Ristorante Qui Si Mangia. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Milan.

If you’re not ready to end the night just yet, Kilburn Cocktail Bar Milano offers a perfect venue to relax and savor a drink. Similarly, Bar Frida is well-suited for those looking to unwind in a social setting. The Friends Pub Milano is another excellent spot to enjoy a nightcap after a delightful meal.

Celebrate another amazing day of your road trip adventure in Italy!

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Day6

Day 6

  • Milan
  • More

Drive 15 km, 1 hour 16 min

  • Piazza Gae Aulenti
  • Pinacoteca di Brera
  • Basilica di Sant'Ambrogio
  • MUDEC - Museum of Cultures
  • More

Day 6 offers an itinerary packed with the best things to see in Pisa. You’ll stay in Milan for 1 night more, offering you enough time to explore at a relaxed pace.

Whether you decide to explore Milan on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Look forward to a unique sightseeing adventure at the notable Piazza Gae Aulenti and allow yourself time to explore. Just a short distance away you'll find your next stop, Pinacoteca Di Brera, a photogenic art gallery that draws visitors from far and near.

Continue your journey to Basilica Di Sant'ambrogio, one of the city’s most popular spots that you shouldn’t miss. Another great site to visit is the well-known Mudec - Museum Of Cultures.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Milan's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delicious dinner at Bice Restaurant, an excellent option for tonight's dining. Looking for something different? Alto Ristorante offers a tantalizing alternative with its diverse menu. And don’t miss Nero 9. Known for great service, it’s a fantastic choice for tonight in Milan.

To truly maximize your evening out, consider visiting Bhangrabar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Rufus Cocktail Bar, another bar with an inviting ambiance. Similarly, Ostello Bello Grande also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Savor another day of unforgettable experiences in Italy!

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Day7

Day 7

  • Milan
  • Priorato
  • Pisa
  • More

Drive 289 km, 3 hours 45 min

  • La Scala
  • Galleria Vittorio Emanuele II
  • Duomo di Milano
  • Rocca Sanvitale
  • More

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Milan and Priorato. When you’re not sightseeing, take time to relax at your chosen hotel in Pisa, where you’ll be staying for 1 night.

To truly experience Milan, make sure to drop by La Scala. This captivating opera house is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Galleria Vittorio Emanuele Ii, one of the city’s best highlights.

Next, check out Duomo Di Milano Museum, one of the most globally renowned places to see in Milan. This church is a favorite among locals and travelers alike.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Priorato. This drive usually takes around 1 hour 24 min, without any stops or traffic disruptions.

Set out on a self-guided sightseeing tour at Rocca Sanvitale and explore the awe-inspiring features.

At the end of the day, you will drive to Pisa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pisa, it's often a good idea to reserve a table in advance.

Savor the flavors at Restaurant -Pizzeria Il Mio Capriccio, a top pick for dinner tonight. Alternatively, Ristorante alle Bandierine beckons with its unique menu offerings. Also, consider Barrique Cocktail And Bistrot. With its consistent customer satisfaction, it’s an excellent option for dining in Pisa tonight.

Continue your evening by exploring the vibrant nightlife scene at Bar Livorno, a prime destination for a thrilling night out.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day8

Day 8

  • Pisa - Departure day
  • More
  • “Tuttomondo” (Keith Haring)
  • More

Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pisa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at “tuttomondo” (keith Haring). This frequently visited art installation is a hotspot among locals.

Take advantage of your accommodation's proximity to Pisa’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pisa.

If you're in the mood to try something new, consider La corte di San Leonardo, another top spot with a mouthwatering menu.

You’ll then say farewell to Pisa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
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Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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