One-Week Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, and Venice

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Spectacular summer view from flying drone Pescara port. Attractive sunset on Adriatic sea. Breathtaking evening scene of Italy, Europe.
View of the Pescara city hall and surrounding buildings, Pescara, Italy.
One-Week Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, and Venice
One-Week Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, and Venice
One-Week Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, and Venice
One-Week Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, and Venice
One-Week Italy Self-Drive Road Trip With Itinerary from Pescara to Rome, Florence, and Venice
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Experience the freedom of the open road on an unforgettable 8-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Pescara, Rome, Florence, Siena, San Gimignano, Venice, and Verona.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Pescara, 2 nights in Rome, 2 nights in Florence, and 1 night in Venice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Pescara, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Pescara, Rome, Florence, Siena, San Gimignano, Venice, and Verona, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Pescara - Arrival day
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  • Ponte del Mare
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Say hello to Pescara! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Pescara for 1 night before you continue your adventure!

Pescara is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ponte Del Mare. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Pescara. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pescara, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Taverna 58, a top-rated dining destination in Pescara. If you're in the mood to try something new, consider Ristorante Carlo Ferraioli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Sesamo Nero. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Pescara this evening.

Explore the vibrant nightlife at Posa Caffè Pescara after your meal, a hub for lively evenings and memorable moments. Or, head to Bar Mixer for a great selection of flavorful drinks and a charming setting. Furthermore, Temple Bar Irish Pub is perfect for those looking to extend their night with a touch of local flavor.

Raise a toast to the start of your 8-day road trip in Italy!

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Day2

Day 2

  • Pescara
  • Rome
  • More

Drive 216 km, 3 hours 24 min

  • Colosseum
  • Roman Forum
  • Castel Sant'Angelo
  • Piazza di Spagna
  • Trevi Fountain
  • More

Your itinerary for day 2 of your road trip in Italy includes 1 stop and features some of the highlights of Rome. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 2 nights.

As you explore Rome’s charming streets, take in the lively atmosphere and get to know the character of the city.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Rome. This drive usually takes around 2 hours 19 min, without any stops or traffic disruptions.

Colosseum is a timeless archeological site we recommend visiting today. Discover its respected features before continuing your self-guided tour to Roman Forum, a picture-perfect archeological site that’s well-regarded in the area.

Next, stop by Castel Sant'angelo, a history-steeped castle. While you’re nearby, don’t forget to visit Piazza Di Spagna, a grand and truly unique public square. End your sightseeing at Trevi Fountain, a wondrous monument that’s highly recommended by travelers passing through the city.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at La Botticella Of Poggi Giovanni, a great choice for enjoying the after-dinner hours with a drink. You could also go to Almalu Trastevere, which offers a similarly pleasant setting and great drinks. Another option is Bar Viminale Di Pepi Maurilio, which provides an inviting environment for unwinding after a busy day out.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day3

Day 3

  • Rome
  • Vatican City
  • More

Drive 9 km, 1 hour 5 min

  • Vatican Museums
  • St Peter's Basilica
  • Sistine Chapel
  • Pantheon
  • Piazza Navona
  • Trastevere
  • More

Wake up to day 3 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Vatican City and Rome. With 1 night to stay in Rome, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Trastevere is a fantastic place you can explore today in Vatican City. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Vatican City-way-of-life and visit all the nearby sights.

Pantheon is perfect for a self-paced visit during the day. This photogenic monument is sure to impress. Next on your list is Piazza Navona, another must-visit landmark and globally renowned public square renowned for its remarkable features.

Once you're ready to continue your road trip, it's time to buckle up and drive towards Vatican City, eagerly anticipating your arrival in Vatican City. This drive usually takes around 12 min, without any stops or traffic disruptions.

Next, make your way to St. Peter's Basilica, another highlight in Vatican City.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Don’t miss out on dining at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Unwind after your meal by stepping into Sant' Eustachio Caffè. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Yellowsquare Rome offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffè Portofino, another top-rated bar in the area.

Relax and recharge in preparation for another adventurous day in Italy!

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Day4

Day 4

  • Rome
  • Florence
  • More

Drive 281 km, 3 hours 51 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • piazza della Signoria
  • More

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 2 nights.

Throughout the day, make sure to take breaks to appreciate the surroundings.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Florence may take around 3 hours 6 min. Upon your arrival in Florence, you’ll be greeted with the opportunity to do some sightseeing and exploring.

For a more meaningful self-guided tour of the city's best attractions, visit Piazzale Michelangelo, an extraordinary observation deck that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Basilica Of Santa Croce In Florence and admire its photogenic features.

When you’re ready, continue to Uffizi Gallery, an extraordinary art gallery beloved by locals and tourists alike. Don't miss out on Ponte Vecchio, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Piazza Della Repubblica, a romantic place to see that you won’t regret spending some extra time discovering.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Ristorante Oliviero 1962, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Di Poneta Novoli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Il Vinile likewise offers a unique atmosphere, perfect for a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day5

Day 5

  • Florence
  • Siena
  • San Gimignano
  • More

Drive 257 km, 4 hours 30 min

  • piazza del Campo
  • Siena Cathedral
  • Villa Calcinaia - Conti Capponi
  • Porta San Giovanni
  • SanGimignano1300
  • More

On day 5 of your road trip in Italy, you’ll start and end your day in Florence, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Florence, there’s no need to rush. Experience Siena, Greti, San Gimignano, and Sant'Andrea to the fullest today with this curated day itinerary.

Whether you decide to explore Siena on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Siena may take around 1 hour 16 min. Upon your arrival in Siena, you’ll be greeted with the opportunity to do some sightseeing and exploring.

When you're ready for some sights, head to Piazza Del Campo, a top-rated public square in Siena. Explore its visually striking features at your own pace before you continue your journey to your next attraction, Siena Cathedral. This interesting church is a top recommendation in the area.

Embrace the thrill of the open road as you wave goodbye to Siena and set your GPS to Greti. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 59 min. Upon reaching Greti, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Villa Calcinaia - Conti Capponi. Spend some time admiring the stunning features of the winery before you continue to your next stop.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in San Gimignano. This drive usually takes around 49 min, without any stops or traffic disruptions.

Porta San Giovanni is a curiosity-inducing monument we recommend visiting today. Discover its breathtaking features before continuing your self-guided tour to Sangimignano1300, a heritage-rich museum that’s well-regarded in the area.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Continue your lively evening at Bar 50 Rosso, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bitter Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Archea Brewery ensures a night out tailored to your taste.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day6

Day 6

  • Florence
  • Venice
  • More

Drive 262 km, 3 hours 37 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Piazza San Marco
  • Rialto Bridge
  • Grand Canal
  • More

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Venice. When you’re not sightseeing, take time to relax at your chosen hotel in Venice, where you’ll be staying for 1 night.

Continue your road trip and head to your next destination, Venice. This car ride takes around 3 hours 19 min.

Savor the day by heading to Bridge Of Sighs, an interesting monument that draws visitors from near and far. When you're done, continue to Doge's Palace, where you can soak in the romantic surroundings.

Next, explore St Mark's Basilica, yet another well-known place to see in the area. After the church, make time to go to Piazza San Marco. This UNESCO world heritage-listed public square is well worth the visit. Lastly, head to Rialto Bridge, an iconic historical landmark you won’t want to miss.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.

Enjoy a delicious meal at Bauer Hotel, a highly-rated dining destination in Venice. If you're eager to try something different, consider L'Osteria Le Guglie, another top spot with a tantalizing menu. You might also want to secure a reservation at Corner Pub. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Venice this evening.

To truly maximize your evening out, consider visiting Al Parlamento after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to The Caffe Rosso, another bar with an inviting ambiance. Similarly, Adagio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Relax and recharge in preparation for another adventurous day in Italy!

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Day7

Day 7

  • Venice
  • Verona
  • Pescara
  • More

Drive 622 km, 6 hours 51 min

  • Ponte Pietra
  • piazza delle Erbe
  • Porta Borsari
  • Verona Arena
  • More

On day 7 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Verona are on today's agenda. In the evening, you’ll end up in Pescara, where you will stay for 1 night.

Fasten your seatbelt and make your way to your next stop — Verona, home to many well-known sights in the region. Keep in mind that your travel time from Venice to Verona may take around 1 hour 23 min without traffic disruptions. Upon arrival in Verona, we highly recommend checking out some of the top attractions.

Set out on a self-guided sightseeing tour at Ponte Pietra and explore the majestic features. Next, make your way to Piazza Delle Erbe, another highlight in Verona. When you’re done exploring the public square, continue to Porta Borsari, a heritage-rich historical landmark.

Nearby, you will also find Verona Arena. This world-famous stadium is a top place to see in the area.

At the end of the day, you will drive to Pescara, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Pescara's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Ciacco, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bar Sara? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante Franco as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Pescara.

Continue the enjoyment post-dinner at Bar Napoli, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Bar Supermarket offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Post Bar. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day8

Day 8

  • Pescara - Departure day
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  • Parrocchia Spirito Santo
  • More

Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Pescara before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Parrocchia Spirito Santo. This beloved church is a hotspot among locals.

For a shopping spree in Pescara, we recommend the lively Centro Commerciale Pescara Porta Nuova. Here, you'll find a range of shops you can browse for some souvenir shopping.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Pescara.

Have a fantastic dining experience at MuuLab. Cucina e Distillati, a highly recommended choice for tonight's dinner. If you're looking to mix things up, La Taverna Antica offers an enticing alternative with its varied menu.

You’ll then say farewell to Pescara. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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