One-Week Italy Self-Drive Road Trip With Itinerary from Naples traveling west to Rome, Siena, Florence, and Viterbo

1 / 109
Twilight panorama of Naples in Italy
Photo of Morning view of Amalfi cityscape on coast line of mediterranean sea, Italy.
One-Week Italy Self-Drive Road Trip With Itinerary from Naples traveling west to Rome, Siena, Florence, and Viterbo
One-Week Italy Self-Drive Road Trip With Itinerary from Naples traveling west to Rome, Siena, Florence, and Viterbo
One-Week Italy Self-Drive Road Trip With Itinerary from Naples traveling west to Rome, Siena, Florence, and Viterbo
One-Week Italy Self-Drive Road Trip With Itinerary from Naples traveling west to Rome, Siena, Florence, and Viterbo
One-Week Italy Self-Drive Road Trip With Itinerary from Naples traveling west to Rome, Siena, Florence, and Viterbo
Perfect travel plans
Everything included
Fully customizable

Description

Included

Flights
Select dates
Hotel
Select dates
Car rental
Select dates
Tours & tickets
Select dates
Travel plan
From A to Z
Travel agent
24/7 fast service

Description

Explore the best of Italy on a remarkable 8-day road trip! Combine exploration with relaxation on a self-drive tour featuring Naples, Rome, Siena, Pisa, Florence, Viterbo, and Caserta.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Naples, 2 nights in Rome, 1 night in Siena, 1 night in Florence, and 1 night in Viterbo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Naples, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Naples, Rome, Siena, Pisa, Florence, Viterbo, and Caserta, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

Read more

Travel details

Set your travel details to find the best price

Flights

Round trip
Round trip
Travel dates

Travelers

Rooms

Flights

Compare and choose from the best flights to Naples

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65
I live in
Pick-up: 10:00
Drop-off: 10:00

Personalize your itinerary

Customize tours under each day and destination

Day1

Day 1

  • Naples - Arrival day
  • More
  • piazza del Plebiscito
  • More

Welcome to Naples, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night discovering what to see in Naples before embarking on the next leg of your journey.

Naples is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Del Plebiscito. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Naples. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at L'Oca Nera Irish Pub, an excellent option for tonight's dining. Looking for something different? Mimì alla Ferrovia offers a tantalizing alternative with its diverse menu. And don’t miss Spuzzulè Winebar. Known for great service, it’s a fantastic choice for tonight in Naples.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Happening Cocktail Bar, a well-loved spot among locals and tourists. Or, head to Shanti Art Musik Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Gran Caffè Gambrinus, another top-rated place in the area.

Raise a toast to the start of your 8-day road trip in Italy!

Read more
Day2

Day 2

  • Naples
  • Rome
  • More

Drive 233 km, 3 hours 16 min

  • Castel Nuovo
  • Cappella Sansevero
  • Piazza Vincenzo Bellini
  • Naples National Archaeological Museum
  • More

On day 2 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Naples are on today's agenda. In the evening, you’ll end up in Rome, where you will stay for 2 nights.

Start your day at Castel Nuovo. This culturally significant castle is a notable place to see in Naples. Then, wander over to Cappella Sansevero. If instagrammable sites excite you, this museum will be right up your alley. Nearby, you’ll also find Piazza Vincenzo Bellini. This picture-perfect public square is a favorite among visitors.

Naples offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Naples National Archaeological Museum is a popular spot in the city that will captivate you with its unique charm.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Dive into a culinary adventure like no other in Rome by booking a table at La Pergola. This popular restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining option, venture to Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Enoteca La Torre, a top local restaurant known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it promises an exceptional dining experience not to be missed.

Unwind after your meal by stepping into La Botticella Of Poggi Giovanni. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Almalu Trastevere offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Bar Viminale Di Pepi Maurilio, another top-rated bar in the area.

Get a good night's sleep and look forward to another great day on the road in Italy!

Read more
Day3

Day 3

  • Rome
  • More

Drive 5 km, 1 hour 8 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Pantheon
  • Piazza Navona
  • More

On day 3 of your road trip, you will have an entire day to discover what to see in Rome. You’ll stay in Rome for 1 night.

Colosseum is perfect for a self-paced visit during the day. This breathtaking archeological site is sure to impress. Next on your list is Roman Forum, another must-visit landmark and wondrous archeological site renowned for its culturally significant features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Trevi Fountain. This romantic monument is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Pantheon, a wondrous monument. Nearby, you'll also find Piazza Navona, ready to add charm to your journey.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue the enjoyment post-dinner at Sant' Eustachio Caffè, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Yellowsquare Rome offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Caffè Portofino. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Take some time to reflect on your day and savor another beautiful night in Italy.

Read more
Day4

Day 4

  • Rome
  • Vatican City
  • Siena
  • More

Drive 247 km, 3 hours 24 min

  • piazza del Popolo
  • Piazza di Spagna
  • St Peter's Basilica
  • More

Your itinerary for day 4 of your road trip in Italy includes 2 stops and features some of the highlights of Rome and Vatican City. At the end of the day, enjoy the comforts of a top-rated hotel in Siena, where you'll spend 1 night.

Awaiting your discovery is the astonishing Piazza Del Popolo, a history-steeped public square in Rome. Next, go to Piazza Di Spagna.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Enoteca I Terzi, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ristorante Tar-Tufo offers an enticing alternative with its varied menu. Additionally, Antica Trattoria Papei is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Siena.

Let the evening flow smoothly from dinner to drinks at Meet Life Cafè, a top-rated bar in the area. For other recommendations, Maudit Pub provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Impero Siena offers a memorable night with diverse drink options and excellent service.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Read more
Day5

Day 5

  • Siena
  • Pisa
  • Florence
  • More

Drive 216 km, 3 hours 30 min

  • piazza del Campo
  • Siena Cathedral
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Campo santo
  • More

Dive into day 5 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Siena and Pisa. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 1 night.

Look forward to a unique sightseeing adventure at the spectacular Piazza Del Campo and allow yourself time to explore. Just a short distance away you'll find your next stop, Siena Cathedral, an enchanting church that draws visitors from far and near.

When you’re ready to jump back into the car and say goodbye to Siena, you’ll hit the road in the direction of Pisa. This drive usually takes around 1 hour 50 min.

Spend your afternoon discovering Leaning Tower Of Pisa, a world-famous monument known for its breathtaking features. Next, continue your sightseeing at Piazza Del Duomo, Pisa, a timeless public square.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Campo Santo and uncover the details of this historic cemetery.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Prepare for an extraordinary culinary adventure in Florence by booking a table at Enoteca Pinchiorri, a 3-star Michelin restaurant that boasts an exceptional italian contemporary menu. For a different flavor experience, head to Santa Elisabetta, renowned for its delectable creative and mediterranean dishes. This 2-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Gucci Osteria da Massimo Bottura, a local gem known for its delightful italian contemporary and international cuisine in Florence. Nestled in the city's heart, this 1-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

To truly maximize your evening out, consider visiting Manifattura after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Se·sto On Arno Rooftop Bar, another bar with an inviting ambiance. Similarly, Il Vinile also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Take some time to reflect on your day and savor another beautiful night in Italy.

Read more
Day6

Day 6

  • Florence
  • Viterbo
  • More

Drive 217 km, 2 hours 59 min

  • piazza della Signoria
  • Uffizi Gallery
  • Ponte Vecchio
  • Cathedral of Santa Maria del Fiore
  • piazzale Michelangelo
  • More

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Florence. When you’re not sightseeing, take time to relax at your chosen hotel in Viterbo, where you’ll be staying for 1 night.

Let Piazza Della Signoria set the tone for the day. Spend some time admiring this enchanting public square before continuing your journey. Uffizi Gallery is your next stop. This widely recognized art gallery is one of the best-rated sights in Florence.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Ponte Vecchio. This romantic historical landmark is a sight to behold. To round off your sightseeing experience, visit Cathedral Of Santa Maria Del Fiore and Piazzale Michelangelo.

When you’re done exploring for the day, you’ll drive to your hotel in Viterbo. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Viterbo's best restaurants.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Read more
Day7

Day 7

  • Viterbo
  • Caserta
  • Naples
  • More

Drive 318 km, 3 hours 43 min

  • Palace of Caserta
  • Giardini Reali - Parco Reggia di Caserta
  • More

Experience an unparalleled adventure on day 7 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Caserta. At the end of the day, you will retreat to the hotel of your choice in Naples, where will spend 1 night.

Embrace the thrill of the open road as you wave goodbye to Viterbo and set your GPS to Caserta. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 53 min. Upon reaching Caserta, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Set out on a self-guided sightseeing tour at Palace Of Caserta and explore the majestic features. Next, make your way to Giardini Reali - Parco Reggia Di Caserta, another highlight in Caserta.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to an extraordinary dining experience at Veritas, a 1-star Michelin restaurant offering an incredible campanian and contemporary menu. Alternatively, if your taste buds call for something different, Il Comandante is one of the best restaurants for creative and mediterranean cuisine in Naples. This 1-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at ARIA. As a top-rated establishment with 1 Michelin star, it is an ideal choice for contemporary and modern cuisine in the city.

Keep the evening going at Archivio Storico - Cocktail Bar & Wonderfood, a great choice for enjoying the after-dinner hours with a drink. You could also go to Archeobar, which offers a similarly pleasant setting and great drinks. Another option is Babette Pub, which provides an inviting environment for unwinding after a busy day out.

Head back to your accommodation in Naples and get some rest to prepare for another magical day of your road trip in Italy.

Read more
Day8

Day 8

  • Naples - Departure day
  • More
  • Ovo Castle
  • More

Day 8 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Naples before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Ovo Castle. This popular castle is a hotspot among locals.

Take advantage of your accommodation's proximity to Naples’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Naples.

Enjoy a lovely meal at Opera Restaurant, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria San Ferdinando is another top choice with a popular menu.

You’ll then say farewell to Naples. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

Read more

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

Similar travel packages

Discover other popular vacations in Italy

Link to appstore phone
Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.