One-Week Italy Self-Drive Road Trip With Itinerary from Brindisi traveling west to Alberobello, Matera, Naples, and Rome

On day 2 of your road trip in Italy, your travel plans include 5 stops at the most scenic, wondrous, and interesting places in the region. Brindisi, Alberobello, Martina Franca, Conversano, and Polignano a Mare are on today's agenda. In the evening, you’ll end up in Alberobello, where you will stay for 1 night.

No visit to Brindisi is complete without Swabian Castle Of Brindisi. This underrated castle is one of the top attractions in the city.

When you’ve had your share of Brindisi, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Alberobello. Your travel time is around 1 hour 1 min.

Spend your afternoon discovering Trulli Di Alberobello Puglia, a notable historical landmark known for its history-steeped features.

When you’re ready to jump back into the car and say goodbye to Alberobello, you’ll hit the road in the direction of Martina Franca. This drive usually takes around 24 min.

For a more meaningful self-guided tour of the city's best attractions, visit Basilica Di San Martino, an underrated church that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Alberobello. Check in and relax before you head out to tour the town.

Alberobello is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Alberobello.

Enjoy a delicious meal at Ristorante "I Primi di Puglia" - Alberobello, a top-rated dining destination in Alberobello.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Matera. At the end of the day, you will retreat to the hotel of your choice in Matera, where will spend 1 night.

Throughout the day, make sure to take breaks to appreciate the surroundings.

When you’ve had your share of Alberobello, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Matera. Your travel time is around 1 hour 16 min.

Spend your afternoon discovering Casa Grotta Del Casalnuovo, a curiosity-inducing cave known for its UNESCO world heritage-designated features. Next, continue your sightseeing at Casa Grotta Nei Sassi Di Matera, an underrated museum.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Church Of Saint Mary Of Idris and uncover the details of this romantic church. Make sure to also explore Sassi Di Matera, a popular archeological site. For your last stop, consider Cattedrale Di Maria Santissima Della Bruna E Sant'eustachio, a stunning church that many travelers find worth the detour.

At the end of the day, you will drive to Matera, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Matera. Enjoy a satisfying meal that will recharge you for tonight's adventures.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pompei and Naples. At the end of the day, you’ll unwind at one of the finest accommodations in Naples, where you'll spend 1 night.

Embrace the thrill of the open road as you wave goodbye to Matera and set your GPS to Pompei. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 51 min. Upon reaching Pompei, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Set out on a self-guided sightseeing tour at Archaeological Park Of Pompeii and explore the picture-perfect features. Next, make your way to Basilica, another highlight in Pompei.

Fasten your seatbelt and make your way to your next stop — Naples, home to many well-known sights in the region. Keep in mind that your travel time from Pompei to Naples may take around 29 min without traffic disruptions. Upon arrival in Naples, we highly recommend checking out some of the top attractions.

For a more meaningful self-guided tour of the town's best attractions, visit Naples National Archaeological Museum, a popular museum that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Piazza Del Plebiscito and admire its enchanting features.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Enjoy a lovely meal at L'Oca Nera Irish Pub, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Mimì alla Ferrovia is another top choice with a popular menu. You could also check for a table at Spuzzulè Winebar. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Naples tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Happening Cocktail Bar, a well-loved spot among locals and tourists. Or, head to Shanti Art Musik Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Gran Caffè Gambrinus, another top-rated place in the area.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Rome. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 2 nights.

Rome’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Naples behind. This drive usually takes around 2 hours 31 min. Rome welcomes you with a multitude of unique vacation experiences.

For a more meaningful self-guided tour of the city's best attractions, visit Colosseum, a timeless archeological site that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Roman Forum and admire its UNESCO world heritage-listed features.

When you’re ready, continue to Trevi Fountain, a globally renowned monument beloved by locals and tourists alike. Don't miss out on Pantheon, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Piazza Navona, a remarkable place to see that you won’t regret spending some extra time discovering.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a wonderful meal at La Bottega Roma, a top-rated dining spot in Rome. If you're in the mood for something new, try Pasta In Corso, another premier location with a delectable menu. You might also want to book a table at Trattoria Vecchia Roma. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

Keep the evening going at La Botticella Of Poggi Giovanni, a great choice for enjoying the after-dinner hours with a drink. You could also go to Almalu Trastevere, which offers a similarly pleasant setting and great drinks. Another option is Bar Viminale Di Pepi Maurilio, which provides an inviting environment for unwinding after a busy day out.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 6 of your road trip, you'll get the chance to experience Vatican City and Rome. At the end of the day, you'll drive back to Rome, where you still have 1 night left to stay.

One of the most iconic spots you can visit today is Trastevere. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.

Make time for Piazza Di Spagna, a timeless public square that is worthwhile a visit in the city. Nearby, you’ll find Spanish Steps, enchanting visitors with its romantic appeal.

Vatican City welcomes you with a multitude of unique vacation experiences.

Vatican Museums is a globally renowned art museum we recommend visiting today.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Rome tonight.

Keep the evening going at Sant' Eustachio Caffè, a great choice for enjoying the after-dinner hours with a drink. You could also go to Yellowsquare Rome, which offers a similarly pleasant setting and great drinks. Another option is Caffè Portofino, which provides an inviting environment for unwinding after a busy day out.

Take some time to reflect on your day and savor another beautiful night in Italy.