7-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling south to Florence and Rome

Day 2 of your road trip across Italy promises a magnificent time exploring what to see in Venice. You have 1 night left in Venice. Take the opportunity to experience more of the best attractions and activities in the city.

One of the most increasingly popular attractions included on the itinerary is Gallerie Dell'accademia. This history-steeped art gallery will help you start your sightseeing on top. Then, take a leisurely stroll to St Mark's Basilica and learn what makes this enchanting church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the wondrous Piazza San Marco. After exploring the public square, head to Doge's Palace. This locally renowned palace is a highlight in Venice. As your day continues, stop by Bridge Of Sighs, known for its symbolic features. Lastly, don’t forget to check out the intriguing Venetian Arsenal. Enjoy exploring this incredible historical landmark at your own pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Generator Venice, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Nevodi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

Keep the excitement of the evening going by visiting a bar or two. Il Mercante is an excellent place to start. You could also check out The Irish Pub Venezia, offering a different kind of charm. A last recommendation for the day is Ai Stagneri. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Relax and look forward to more memorable moments to come!

Dive into day 3 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Florence. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 2 nights.

As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Florence may take around 2 hours 56 min. Upon your arrival in Florence, you’ll be greeted with the opportunity to do some sightseeing and exploring.

One of our top recommendations for your sightseeing is Bargello National Museum. Spend some time admiring the detailed features of the museum before you continue to your next stop. Then, head to Basilica Of Santa Croce In Florence. This notable church is a traveler-favorite in the city.

If you're keen to see more, continue to Uffizi Gallery. Feed your curiosity by learning something new about the art gallery. Next, take your journey to Ponte Vecchio, an iconic historical landmark. Conclude your sightseeing at Piazza Della Signoria, known for its enchanting features.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Di Poneta Novoli, another premier location with a delectable menu. You might also want to book a table at Caffe San Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Keep the evening going at Manifattura, a great choice for enjoying the after-dinner hours with a drink. You could also go to Se·sto On Arno Rooftop Bar, which offers a similarly pleasant setting and great drinks. Another option is Il Vinile, which provides an inviting environment for unwinding after a busy day out.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Greet day 4 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Florence, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Florence, Siena, and Pisa.

Cathedral Of Santa Maria Del Fiore is perfect for a self-paced visit during the day. This inviting church is sure to impress. Next on your list is Galleria Dell'accademia, another must-visit landmark and captivating art gallery renowned for its detailed features.

Embrace the thrill of the open road as you wave goodbye to Florence and set your GPS to Siena. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 15 min. Upon reaching Siena, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

When you're ready for some sights, head to Piazza Del Campo, a spectacular public square in Siena. Explore its UNESCO world heritage-listed features at your own pace before you continue your journey.

Fasten your seatbelt and make your way to your next stop — Pisa, home to many well-known sights in the region. Keep in mind that your travel time from Siena to Pisa may take around 1 hour 53 min without traffic disruptions. Upon arrival in Pisa, we highly recommend checking out some of the top attractions.

Our first attraction recommendation in Pisa is Leaning Tower Of Pisa, a wondrous monument that draws attention for its culturally significant features.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Ditta Artigianale, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria Da Burde boasts a menu that's sure to impress. Also, be sure to check out Casa Toscana. Known as a local hotspot, it’s a great choice for tonight in Florence.

To truly maximize your evening out, consider visiting Bar 50 Rosso after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bitter Bar, another bar with an inviting ambiance. Similarly, Archea Brewery also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Celebrate another amazing day of your road trip adventure in Italy!

Your itinerary for day 5 of your road trip in Italy includes 2 stops and features some of the highlights of Rome and Vatican City. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 1 night.

Rome’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Florence behind. This drive usually takes around 3 hours 7 min. Rome welcomes you with a multitude of unique vacation experiences.

Savor the day by heading to Pantheon, an iconic monument that draws visitors from near and far. When you're done, continue to Trevi Fountain, where you can soak in the enchanting surroundings.

Next, explore Spanish Steps, yet another spectacular place to see in the area.

Fasten your seatbelt and make your way to your next stop — Vatican City, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Vatican City may take around 14 min without traffic disruptions. Upon arrival in Vatican City, we highly recommend checking out some of the top attractions.

For a more meaningful self-guided tour of the city's best attractions, visit St. Peter's Basilica, a wondrous major basilica that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at La Bottega Roma, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Pasta In Corso, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria Vecchia Roma. It’s yet another ideal choice to enhance your time in Rome tonight.

Continue the enjoyment post-dinner at La Botticella Of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Almalu Trastevere offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Viminale Di Pepi Maurilio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Get a good night's sleep and look forward to another great day on the road in Italy!

Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Bologna. At the end of the day, you will retreat to the hotel of your choice in Venice, where will spend 1 night.

Fasten your seatbelt and make your way to your next stop — Bologna, home to many well-known sights in the region. Keep in mind that your travel time from Rome to Bologna may take around 4 hours 7 min without traffic disruptions. Upon arrival in Bologna, we highly recommend checking out some of the top attractions.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Fountain Of Neptune, Bologna, an underrated monument that everyone visiting Bologna should see. Next, head to Bologna Cathedral. This culturally significant church is one of the most worthwhile attractions in the region.

If you're keen to see more, don’t miss out on Piazza Maggiore, an enchanting public square popular among locals as well as travelers. Two Towers is an excellent attraction to visit next. Spend some time learning more about this interesting monument before you continue your journey. Lastly, visit Piazza Santo Stefano, an inviting public square and a top attraction in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Osteria Alla Staffa, a top recommendation for dinner tonight. Or, for a change of pace, Bistrot de Venise boasts a menu that's sure to impress. Also, be sure to check out Corte Sconta. Known as a local hotspot, it’s a great choice for tonight in Venice.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Dolce Vita Venezia, known for its inviting atmosphere. Tarnowska's American Bar is another great option if you’re looking for a place to get the night started. Similarly, Bar All'angolo provides a great setting to enjoy the night away.

Relax and recharge in preparation for another adventurous day in Italy!