7-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome and Florence

On day 2 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Rome are on today's agenda. In the evening, you’ll end up in Rome, where you will stay for 2 nights.

Embrace the thrill of the open road as you wave goodbye to Pescara and set your GPS to Rome. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 19 min. Upon reaching Rome, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

For a more meaningful self-guided tour of the city's best attractions, visit Colosseum, a wondrous archeological site that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Roman Forum and admire its picture-perfect features.

When you’re ready, continue to Pantheon, a globally renowned monument beloved by locals and tourists alike. Don't miss out on Spanish Steps, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Piazza Di Spagna, a visually striking place to see that you won’t regret spending some extra time discovering.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Explore the vibrant nightlife at La Botticella Of Poggi Giovanni after your meal, a hub for lively evenings and memorable moments. Or, head to Almalu Trastevere for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Viminale Di Pepi Maurilio is perfect for those looking to extend their night with a touch of local flavor.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 3 of your road trip, you'll get the chance to experience Vatican City and Rome. At the end of the day, you'll drive back to Rome, where you still have 1 night left to stay.

One of the most iconic spots you can visit today is Trastevere. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby. You can also explore Monti, a neighborhood that offers a glimpse into local life and culture.

Visiting Piazza Navona is always a good idea. This wondrous public square is a place that is appreciated by travelers and locals alike.

It’s time to gear up for the next part of your road trip adventure. Set course for Vatican City! Under favorable conditions, your drive to Vatican City may take around 21 min. Upon your arrival in Vatican City, you’ll be greeted with the opportunity to do some sightseeing and exploring.

For a more meaningful self-guided tour of the city's best attractions, visit St. Peter's Basilica, an iconic major basilica that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re ready, continue to Vatican Museums, a world-famous art museum beloved by locals and tourists alike.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Enjoy a lovely meal at RomAntica, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Coso Ristorante is another top choice with a popular menu. You could also check for a table at DEROMA - Farine Romane. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Rome tonight.

Let the evening flow smoothly from dinner to drinks at Sant' Eustachio Caffè, a top-rated bar in the area. For other recommendations, Yellowsquare Rome provides a perfect setting for rounding out your night with style and great drinks. Likewise, Caffè Portofino offers a memorable night with diverse drink options and excellent service.

Relax and recharge in preparation for another adventurous day in Italy!

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Florence. When you’re not sightseeing, take time to relax at your chosen hotel in Florence, where you’ll be staying for 2 nights.

As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city.

When you’re ready to jump back into the car and say goodbye to Rome, you’ll hit the road in the direction of Florence. This drive usually takes around 3 hours 2 min.

Our first attraction recommendation in Florence is Basilica Of Santa Croce In Florence, a well-known church that draws attention for its photogenic features. Spend some time soaking in the atmosphere before continuing to Uffizi Gallery, a history-steeped art gallery that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Ponte Vecchio, a globally renowned historical landmark that offers a unique experience. Be sure to also explore Piazza Della Repubblica, a nearby public square, highly recommended by other travelers. End your self-guided tour at Cathedral Of Santa Maria Del Fiore, a history-steeped church and the perfect final attraction in Florence.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Ristorante Oliviero 1962, an excellent option for tonight's dining. Looking for something different? Di Poneta Novoli offers a tantalizing alternative with its diverse menu. And don’t miss Caffe San Firenze. Known for great service, it’s a fantastic choice for tonight in Florence.

After savoring a delicious meal, step into the vibrant nightlife at Manifattura, where the evening is just getting started. In the same way, Se·sto On Arno Rooftop Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Il Vinile is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Celebrate another amazing day of your road trip adventure in Italy!

Wake up to day 5 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Pisa and Florence. With 1 night to stay in Florence, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Pisa is brimming with adventures.

Make time for Central Market, an interesting food market that is worthwhile a visit in the city. Nearby, you’ll find Piazzale Michelangelo, enchanting visitors with its visually striking appeal.

After soaking in Florence’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Pisa. Expect your car journey to take a minimum of 1 hour 16 min. When you arrive in Pisa, it's time to take a break from the road.

Savor the day by heading to Piazza Del Duomo, Pisa, a timeless public square that draws visitors from near and far. When you're done, continue to Pisa Cathedral, where you can soak in the stunning surroundings.

Next, explore Leaning Tower Of Pisa, yet another world-famous place to see in the area. After the monument, make time to go to Angelo Caduto.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

After enjoying a fulfilling meal, continue your evening at Bar 50 Rosso, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bitter Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Archea Brewery provides an excellent environment for a relaxed and enjoyable evening.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Santa Maria degli Angeli. At the end of the day, you will retreat to the hotel of your choice in Pescara, where will spend 1 night.

Fasten your seatbelt and make your way to your next stop — Santa Maria degli Angeli, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Santa Maria degli Angeli may take around 2 hours 7 min without traffic disruptions. Upon arrival in Santa Maria degli Angeli, we highly recommend checking out some of the top attractions.

Set out on a self-guided sightseeing tour at Basilica Of San Francesco D'assisi and explore the majestic features. Next, make your way to Portico Of Monte Frumentario, another highlight in Santa Maria degli Angeli. When you’re done exploring the historical landmark, continue to Church Of Santa Maria Sopra Minerva In Assisi, a culturally significant church.

Nearby, you will also find Piazza Del Comune. This intriguing public square is a top place to see in the area. Lastly, head to Rocca Maggiore, an enchanting castle that is perfect for some final exploring in the town.

When you’re done exploring for the day, you’ll drive to your hotel in Pescara. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Pescara's best restaurants.

Dine in style at Ciacco, a top recommendation for dinner tonight. Or, for a change of pace, Bar Sara boasts a menu that's sure to impress. Also, be sure to check out Ristorante Franco. Known as a local hotspot, it’s a great choice for tonight in Pescara.

Keep the excitement of the evening going by visiting a bar or two. Bar Napoli is an excellent place to start. You could also check out Bar Supermarket, offering a different kind of charm. A last recommendation for the day is Post Bar. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Say good night to Pescara and look forward to another great day of your road trip in Italy!