7-Day Italy Self-Drive Road Trip With Itinerary from Pescara to Rome and Florence

Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Rome. At the end of the day, you will retreat to the hotel of your choice in Rome, where will spend 2 nights.

When you’ve had your share of Pescara, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Rome. Your travel time is around 2 hours 19 min.

One of our top recommendations for your sightseeing is Colosseum. Spend some time admiring the UNESCO world heritage-designated features of the archeological site before you continue to your next stop. Then, head to Roman Forum. This timeless archeological site is a traveler-favorite in the city.

If you're keen to see more, continue to Pantheon. Feed your curiosity by learning something new about the monument. Next, take your journey to Spanish Steps, a famous public square. Conclude your sightseeing at Piazza Di Spagna, known for its grand features.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at La Bottega Roma, a top-rated dining spot in Rome. If you're in the mood for something new, try Pasta In Corso, another premier location with a delectable menu. You might also want to book a table at Trattoria Vecchia Roma. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Relax and recharge in preparation for another adventurous day in Italy!

Greet day 3 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Rome, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Vatican City and Rome.

Trastevere is one of the highlights of today. Take your time exploring this iconic neighborhood in Vatican City, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city. Be sure to also visit Monti, a neighborhood that showcases another side of Vatican City.

Make time for Piazza Navona, a timeless public square that is worthwhile a visit in the city.

Vatican City’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Rome behind. This drive usually takes around 21 min. Vatican City welcomes you with a multitude of unique vacation experiences.

For a more meaningful self-guided tour of the city's best attractions, visit St. Peter's Basilica, a timeless major basilica that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re ready, continue to Vatican Museums, a world-famous art museum beloved by locals and tourists alike.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Explore the vibrant nightlife at Sant' Eustachio Caffè after your meal, a hub for lively evenings and memorable moments. Or, head to Yellowsquare Rome for a great selection of flavorful drinks and a charming setting. Furthermore, Caffè Portofino is perfect for those looking to extend their night with a touch of local flavor.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Florence. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 2 nights.

When you’re ready to jump back into the car and say goodbye to Rome, you’ll hit the road in the direction of Florence. This drive usually takes around 3 hours 2 min.

Savor the day by heading to Basilica Of Santa Croce In Florence, an interesting church that draws visitors from near and far. When you're done, continue to Uffizi Gallery, where you can soak in the romantic surroundings.

Next, explore Ponte Vecchio, yet another iconic place to see in the area. After the historical landmark, make time to go to Piazza Della Repubblica. This respected public square is well worth the visit. Lastly, head to Cathedral Of Santa Maria Del Fiore, a spectacular church you won’t want to miss.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Treat yourself to a delicious dinner at Ristorante Oliviero 1962, an excellent option for tonight's dining. Looking for something different? Di Poneta Novoli offers a tantalizing alternative with its diverse menu. And don’t miss Caffe San Firenze. Known for great service, it’s a fantastic choice for tonight in Florence.

Extend your evening after a delightful meal by visiting Manifattura, which offers the perfect atmosphere for a night out. Moreover, Se·sto On Arno Rooftop Bar is another popular option for a drink or two. Likewise, Il Vinile also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 5 of your road trip, you'll get the chance to experience Pisa and Florence. At the end of the day, you'll drive back to Florence, where you still have 1 night left to stay.

Make a stop at Central Market. This interesting food market is a must-visit for travelers looking for a unique holiday experience. Make your way to Piazzale Michelangelo located in Florence for another exciting encounter.

When you’ve had your share of Florence, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Pisa. Your travel time is around 1 hour 16 min.

Savor the day by heading to Piazza Del Duomo, Pisa, a timeless public square that draws visitors from near and far. When you're done, continue to Pisa Cathedral, where you can soak in the majestic surroundings.

Next, explore Leaning Tower Of Pisa, yet another wondrous place to see in the area. After the monument, make time to go to Angelo Caduto.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Ditta Artigianale, a highly-rated dining destination in Florence. If you're eager to try something different, consider Trattoria Da Burde, another top spot with a tantalizing menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and recharge in preparation for another adventurous day in Italy!

On day 6 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Santa Maria degli Angeli are on today's agenda. In the evening, you’ll end up in Pescara, where you will stay for 1 night.

Fasten your seatbelt and make your way to your next stop — Santa Maria degli Angeli, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Santa Maria degli Angeli may take around 2 hours 7 min without traffic disruptions. Upon arrival in Santa Maria degli Angeli, we highly recommend checking out some of the top attractions.

Basilica Of San Francesco D'assisi is a locally renowned church we recommend visiting today. Discover its historic features before continuing your self-guided tour to Portico Of Monte Frumentario, a culturally significant historical landmark that’s well-regarded in the area.

Next, stop by Church Of Santa Maria Sopra Minerva In Assisi, a photogenic church. While you’re nearby, don’t forget to visit Piazza Del Comune, a visually striking and truly unique public square. End your sightseeing at Rocca Maggiore, an often recommended castle that’s highly recommended by travelers passing through the town.

At the end of the day, you will drive to Pescara, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Pescara's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Ciacco, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bar Sara? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante Franco as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Pescara.

Explore the vibrant nightlife at Bar Napoli after your meal, a hub for lively evenings and memorable moments. Or, head to Bar Supermarket for a great selection of flavorful drinks and a charming setting. Furthermore, Post Bar is perfect for those looking to extend their night with a touch of local flavor.

Celebrate another amazing day of your road trip adventure in Italy!