7-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence

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Genoa seaport, Italy
Photo of Sand beach in Camogli by Genoa, Italy.
7-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence
7-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence
7-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence
7-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence
7-Day Italy Self-Drive Road Trip With Itinerary from Genoa to Florence
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Experience the freedom of the open road on an unforgettable 7-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Genoa, Manarola, Corniglia, Vernazza, Pisa, Florence, Siena, and Lucca.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 4 nights in Genoa and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Genoa, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Ponte Vecchio and Leaning Tower Of Pisa are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Genoa, Manarola, Corniglia, Vernazza, Pisa, Florence, Siena, and Lucca, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Genoa - Arrival day
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  • porto antico
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Your road trip adventure in Italy begins as soon as you reach Genoa and pick up your car. You’ll stay here for 3 nights and explore what to see in Genoa, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Genoa is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Porto Antico. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Genoa. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Genoa, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at 7 Sensi cucina decontaminata, a popular restaurant in Genoa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Genoa at Alla Lunga Ristorante, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Grand Hotel Savoia. It’s yet another ideal choice to enhance your time in Genoa tonight.

Let the evening flow smoothly from dinner to drinks at Scurreria Beer & Bagel, a top-rated bar in the area. For other recommendations, La Lepre provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Pisacane Iii offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 7-day road trip in Italy!

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Day2

Day 2

  • Genoa
  • More

Drive 11 km, 48 min

  • Lighthouse of Genoa
  • Galata - Museo del mare
  • Aquarium of Genoa
  • Genoa Cathedral
  • Doge's Palace
  • piazza De Ferrari
  • More

Day 2 of your road trip across Italy promises a magnificent time exploring what to see in Genoa. You have 2 nights left in Genoa. Take the opportunity to experience more of the best attractions and activities in the city.

Whatever your travel style is, Lighthouse Of Genoa is an essential stop in Genoa. This worthwhile lighthouse provides an insightful glimpse into the city's identity. Next, discover Galata Museo Del Mare (complex), a photogenic maritime museum, promising a delightful encounter.

Continue your sightseeing with a visit to Aquarium Of Genoa, an astonishing aquarium. When you’re done, don’t forget to make a stop at the underrated Genoa Cathedral. Not far away from the church, you will find the romantic Piazza De Ferrari, perfect for a quick visit.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Zeffirino, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Vegia Zena offers an enticing alternative with its varied menu. Additionally, Trattoria delle Grazie is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Genoa.

Relax and look forward to more memorable moments to come!

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Day3

Day 3

  • Genoa
  • Manarola
  • Corniglia
  • Vernazza
  • More

Drive 249 km, 4 hours 46 min

  • Manarola Overlook Viewpoint
  • Cinque Terre National Park
  • Ruins of Doria Tower
  • Church of St. Margaret of Antioch
  • Scalinata Lardarina
  • More

On day 3 of your road trip in Italy, you’ll start and end your day in Genoa, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Genoa, there’s no need to rush. Experience Manarola, Corniglia, and Vernazza to the fullest today with this curated day itinerary.

Set your GPS to Manarola and hit the road. Expect a journey of approximately 2 hours 6 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Manarola beckons with new experiences!

For a more meaningful self-guided tour of the village's best attractions, visit Manarola Overlook Viewpoint, a worthwhile observation deck that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

Corniglia’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Manarola behind. This drive usually takes around 15 min. Corniglia welcomes you with a multitude of unique vacation experiences.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Cinque Terre National Park, a locally renowned national park that everyone visiting Corniglia should see. Next, head to Scalinata Lardarina. This enchanting hiking area is one of the most frequently visited attractions in the region.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Vernazza.

When you're ready for some sights, head to Ruins Of Doria Tower, an underrated monument in Vernazza. Explore its visually striking features at your own pace before you continue your journey to your next attraction, Church Of St. Margaret Of Antioch. This often recommended church is a top recommendation in the area.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Genoa.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely meal at Osteria Sant'Ilario, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, La Cialtroneria is another top choice with a popular menu. You could also check for a table at Manhattan Bar. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Genoa tonight.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day4

Day 4

  • Genoa
  • Pisa
  • Florence
  • More

Drive 271 km, 3 hours 58 min

  • “Tuttomondo” (Keith Haring)
  • Santa Maria della Spina
  • Knights' Square
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • More

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Pisa. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 2 nights.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Pisa may take around 1 hour 57 min. Upon your arrival in Pisa, you’ll be greeted with the opportunity to do some sightseeing and exploring.

For a more meaningful self-guided tour of the city's best attractions, visit “tuttomondo” (keith Haring), an underrated art installation that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Santa Maria Della Spina and admire its enchanting features.

When you’re ready, continue to Knights' Square, an intriguing public square beloved by locals and tourists alike. Don't miss out on Leaning Tower Of Pisa, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Piazza Del Duomo, Pisa, a breathtaking place to see that you won’t regret spending some extra time discovering.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Ristorante Oliviero 1962, an excellent option for tonight's dining. Looking for something different? Di Poneta Novoli offers a tantalizing alternative with its diverse menu. And don’t miss Caffe San Firenze. Known for great service, it’s a fantastic choice for tonight in Florence.

If you’re not ready to end the night just yet, Manifattura offers a perfect venue to relax and savor a drink. Similarly, Se·sto On Arno Rooftop Bar is well-suited for those looking to unwind in a social setting. Il Vinile is another excellent spot to enjoy a nightcap after a delightful meal.

Say good night to Florence and look forward to another great day of your road trip in Italy!

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Day5

Day 5

  • Florence
  • More

Drive 8 km, 1 hour 2 min

  • Cathedral of Santa Maria del Fiore
  • piazza della Signoria
  • Ponte Vecchio
  • Uffizi Gallery
  • Basilica of Santa Croce in Florence
  • piazzale Michelangelo
  • More

On day 5 of your road trip, you will have an entire day to discover what to see in Florence. You’ll stay in Florence for 1 night.

Start your day at Cathedral Of Santa Maria Del Fiore. This romantic church is a famous place to see in Florence. Then, wander over to Piazza Della Signoria. If majestic sites excite you, this public square will be right up your alley. Nearby, you’ll also find Ponte Vecchio. This respected historical landmark is a favorite among visitors.

Florence offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Uffizi Gallery is a famous spot in the city that will captivate you with its unique charm. When you’re done at the art gallery, don’t forget to check out the culturally significant Basilica Of Santa Croce In Florence. Take a moment to appreciate the fascinating details of this notable church. Wrap up your self-guided tour of Florence's top attractions with a visit to Piazzale Michelangelo.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Ditta Artigianale, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Trattoria Da Burde is another top choice with a popular menu. You could also check for a table at Casa Toscana. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

Unwind after your meal by stepping into Bar 50 Rosso. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Bitter Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Archea Brewery, another top-rated bar in the area.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day6

Day 6

  • Florence
  • Siena
  • Lucca
  • Genoa
  • More

Drive 380 km, 4 hours 59 min

  • Siena Cathedral
  • piazza del Campo
  • Walls of Lucca
  • Porta San Pietro
  • More

Dive into day 6 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Siena and Lucca. At the end of the day, you’ll unwind at one of the finest accommodations in Genoa, where you'll spend 1 night.

Set your GPS to Siena and hit the road. Expect a journey of approximately 1 hour 12 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Siena beckons with new experiences!

One of our top recommendations for your sightseeing is Siena Cathedral. Spend some time admiring the history-steeped features of the church before you continue to your next stop. Then, head to Piazza Del Campo. This extraordinary public square is a traveler-favorite in the city.

Fasten your seatbelt and make your way to your next stop — Lucca, home to many well-known sights in the region. Keep in mind that your travel time from Siena to Lucca may take around 1 hour 50 min without traffic disruptions. Upon arrival in Lucca, we highly recommend checking out some of the top attractions.

For a more meaningful self-guided tour of the city's best attractions, visit Mura Di Lucca, a curiosity-inducing historical landmark that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Porta San Pietro and admire its historic features.

When you’re done exploring for the day, you’ll drive to your hotel in Genoa. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Genoa's most popular restaurants, and connect with friendly locals for a true cultural experience.

Savor the flavors at Vivarelli, a top pick for dinner tonight. Alternatively, Trattoria Ugo beckons with its unique menu offerings. Also, consider TAZZE PAZZE Specialty Coffee. With its consistent customer satisfaction, it’s an excellent option for dining in Genoa tonight.

Head back to your accommodation in Genoa and get some rest to prepare for another magical day of your road trip in Italy.

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Day7

Day 7

  • Genoa - Departure day
  • More
  • Via Garibaldi
  • More

Day 7 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Genoa before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Via Garibaldi. This underrated street is a hotspot among locals.

For a shopping spree in Genoa, we recommend the lively Via Garibaldi. Here, you'll find a range of shops you can browse for some souvenir shopping. Discover boutiques with stylish fashion choices to upgrade your wardrobe.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Genoa.

Dine in style at Bar Festival, a top recommendation for dinner tonight. Or, for a change of pace, Il Marin boasts a menu that's sure to impress.

You’ll then say farewell to Genoa. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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