6-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling east to Salerno and Naples

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Colosseum, Rome, Italy.
Photo of piazza de spagna in Rome, Italy.
6-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling east to Salerno and Naples
6-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling east to Salerno and Naples
6-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling east to Salerno and Naples
6-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling east to Salerno and Naples
6-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling east to Salerno and Naples
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Explore the best of Italy on a remarkable 6-day road trip! Combine exploration with relaxation on a self-drive tour featuring Rome, Salerno, Amalfi, Pompei, and Naples.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Rome, 1 night in Salerno, and 1 night in Naples. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Salerno, Amalfi, Pompei, and Naples, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Rome - Arrival day
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  • Piazza Navona
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Welcome to Rome, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Rome before embarking on the next leg of your journey.

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Navona. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Rome. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Following your dinner, dive into the local bar culture at La Botticella Of Poggi Giovanni. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Almalu Trastevere, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise a toast to the start of your 6-day road trip in Italy!

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Day2

Day 2

  • Rome
  • More

Drive 13 km, 1 hour 8 min

  • Castel Sant'Angelo
  • Pantheon
  • Trevi Fountain
  • Piazza di Spagna
  • Spanish Steps
  • More

Day 2 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Rome.

Whether you decide to explore Rome on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Experience Castel Sant'angelo, an impressive castle in the city. Then, head to Pantheon and soak in the ambiance of this photogenic monument.

There are many interesting places to see in Rome, and when you are ready for more, go to Trevi Fountain. This is one of the city’s most iconic symbolic spots of interest. After exploring the monument, visit the iconic Piazza Di Spagna. Not far away, you'll also find Spanish Steps. This public square is a majestic highlight in Rome.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

For an unforgettable shopping experience, visit Galleria San Pietro, the top shopping destination in Rome. Browse local shops and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Galleria San Pietro has to offer, including attractions, essential services, and vibrant community activities.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Discover the culinary delights of Rome by securing a reservation at La Pergola. Esteemed for its 3-star Guide Michelin recognition, this restaurant offers a remarkable selection of mediterranean and contemporary cuisine. For an alternative dining experience, try Il Pagliaccio, renowned for its delicious creative and innovative dishes. This esteemed 2-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to Enoteca La Torre, a highly recommended local eatery celebrated for its mouthwatering mediterranean and creative menu. With its 2-star Michelin recognition, it offers an unforgettable dining adventure.

Unwind after your meal by stepping into Sant' Eustachio Caffè. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Yellowsquare Rome offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffè Portofino, another top-rated bar in the area.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day3

Day 3

  • Rome
  • Salerno
  • More

Drive 277 km, 3 hours 35 min

  • Roman Forum
  • Colosseum
  • piazza del Popolo
  • Villa Borghese
  • More

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Rome. At the end of the day, you will retreat to the hotel of your choice in Salerno, where will spend 1 night.

Make a stop at Roman Forum. This wondrous archeological site is a must-visit for travelers looking for a unique holiday experience. Make your way to Colosseum located in Rome for another exciting encounter.

Next, immerse yourself in the setting of Piazza Del Popolo. Its symbolic features will captivate you. After the public square, continue your tour of the city with a visit to Villa Borghese. Visitors usually appreciate the mesmerizing features of this park.

When you’re done exploring for the day, you’ll drive to your hotel in Salerno. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Salerno, it's often a good idea to reserve a table in advance.

Treat yourself to an extraordinary dining experience at Re Maurì, a 1-star Michelin restaurant offering an incredible creative menu. Alternatively, if your taste buds call for something different, L'Unico Drink & Food Salerno is another top choice with a popular menu.

To truly maximize your evening out, consider visiting Hilton Bar E Gastronomia after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to The Black Monday Speakeasy Tbm, another bar with an inviting ambiance. Similarly, Dòmo I' Vinaino Wine Bar - Enogastronomia also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Celebrate another amazing day of your road trip adventure in Italy!

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Day4

Day 4

  • Salerno
  • Amalfi
  • Pompei
  • Naples
  • More

Drive 88 km, 2 hours 39 min

  • Cattedrale di Santa Maria degli Angeli, San Matteo e San Gregorio VII
  • Amalfi Coast
  • Archaeological Park of Pompeii
  • Temple of Venus
  • Basilica
  • More

On day 4 of your road trip in Italy, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Salerno, Amalfi, and Pompei are on today's agenda. In the evening, you’ll end up in Naples, where you will stay for 1 night.

Enjoy all that Cathedral Of Santa Maria Degli Angeli, San Matteo And San Gregorio Vii has to offer. This is an often recommended church you should not miss.

Amalfi’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Salerno behind. This drive usually takes around 59 min. Amalfi welcomes you with a multitude of unique vacation experiences.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Amalfi Coast, an extraordinary coast that everyone visiting Amalfi should see.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Pompei may take around 1 hour 3 min. Upon your arrival in Pompei, you’ll be greeted with the opportunity to do some sightseeing and exploring.

One of our top recommendations for your sightseeing is Archaeological Park Of Pompeii. Spend some time admiring the breathtaking features of the archeological site before you continue to your next stop. Then, head to Temple Of Venus. This frequently visited archeological site is a traveler-favorite in the city.

If you're keen to see more, continue to Basilica. Feed your curiosity by learning something new about the archeological site.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Naples is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Naples.

Set out on a gastronomic journey in Naples by reserving a table at Veritas. Renowned for its 1-star Michelin recognition, this restaurant presents an outstanding menu of campanian and contemporary cuisine. For a different taste, head over to Il Comandante, renowned for its delectable creative and mediterranean dishes. This distinguished 1-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore ARIA, a highly rated local gem known for its exquisite contemporary and modern menu. With a 1-star Michelin acclaim, it promises a dining experience you won't want to miss.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Happening Cocktail Bar, known for its inviting atmosphere. Shanti Art Musik Bar is another great option if you’re looking for a place to get the night started. Similarly, Gran Caffè Gambrinus provides a great setting to enjoy the night away.

Relax and recharge in preparation for another adventurous day in Italy!

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Day5

Day 5

  • Naples
  • Vatican City
  • Rome
  • More

Drive 238 km, 2 hours 56 min

  • piazza del Plebiscito
  • St Peter's Basilica
  • More

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Naples and Vatican City. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 1 night.

To truly experience Naples, make sure to drop by Piazza Del Plebiscito. This impressive public square is a must-visit for anyone seeking a unique vacation experience.

When you’ve had your share of Naples, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Vatican City, Vatican City. Your travel time is around 14 min.

When you're ready for some sights, head to St. Peter's Basilica, a timeless major basilica in Vatican City.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Following your dinner, dive into the local bar culture at The Apartment Bar Roma. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Hotel Hassler Roma, the perfect place for those looking to experience the best of the nightlife.

Raise your glass to another unforgettable day in Italy!

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Day6

Day 6

  • Rome - Departure day
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  • Altare della Patria
  • More

Day 6 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Altare Della Patria. This notable monument is a hotspot among locals.

Take some time to indulge in shopping at Rome’s popular marketplace, Trastevere. Look for keepsakes or souvenirs to remind you of your trip. Browse boutiques to find unique and stylish fashion pieces.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

Dine in style at Sofitel Roma Villa Borghese, a top recommendation for dinner tonight. Or, for a change of pace, Centro boasts a menu that's sure to impress.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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