6-Day Italy Self-Drive Road Trip With Itinerary from Naples to Rome and Florence

Greet day 2 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Naples, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Pompei, Amalfi, Positano, Ravello, and Naples.

Your adventure in Naples is only getting started when you visit Ovo Castle, a captivating local hot spot.

Embrace the thrill of the open road as you wave goodbye to Naples and set your GPS to Pompei. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 27 min. Upon reaching Pompei, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Archaeological Park Of Pompeii. Spend some time admiring the UNESCO world heritage-designated features of the archeological site before you continue to your next stop.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Amalfi. This drive usually takes around 1 hour 10 min, without any stops or traffic disruptions.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Amalfi Coast, a spectacular coast that everyone visiting Amalfi should see.

After soaking in Amalfi’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Positano. Expect your car journey to take a minimum of 47 min. When you arrive in Positano, it's time to take a break from the road.

Costiera Amalfitana Positano is an up-and-coming beach we recommend visiting today. Discover its eye-catching features before continuing your self-guided tour.

When you’re done exploring for the day, you’ll return to Naples and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Savor the flavors at Antica Pizzeria Di Matteo, a top pick for dinner tonight. Alternatively, Mercure Napoli Centro Angioino beckons with its unique menu offerings. Also, consider La Lazzara Trattoria e Pizzeria. With its consistent customer satisfaction, it’s an excellent option for dining in Naples tonight.

Continue your lively evening at Archivio Storico - Cocktail Bar & Wonderfood, a perfect place for winding down or revving up the night, depending on which mood you’re in. Archeobar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Babette Pub ensures a night out tailored to your taste.

Savor another day of unforgettable experiences in Italy!

Your itinerary for day 3 of your road trip in Italy includes 2 stops and features some of the highlights of Rome and Vatican City. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 1 night.

When you’ve had your share of Naples, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Rome. Your travel time is around 2 hours 31 min.

Set out on a self-guided sightseeing tour at Colosseum and explore the historic features. Next, make your way to Roman Forum, another highlight in Rome. When you’re done exploring the archeological site, continue to Trevi Fountain, a visually striking monument.

Nearby, you will also find Pantheon. This wondrous monument is a top place to see in the area.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Enjoy a delicious meal at La Bottega Roma, a highly-rated dining destination in Rome. If you're eager to try something different, consider Pasta In Corso, another top spot with a tantalizing menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

To truly maximize your evening out, consider visiting La Botticella Of Poggi Giovanni after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Almalu Trastevere, another bar with an inviting ambiance. Similarly, Bar Viminale Di Pepi Maurilio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Florence. When you’re not sightseeing, take time to relax at your chosen hotel in Florence, where you’ll be staying for 1 night.

Fasten your seatbelt and make your way to your next stop — Florence, home to many well-known sights in the region. Keep in mind that your travel time from Rome to Florence may take around 3 hours 6 min without traffic disruptions. Upon arrival in Florence, we highly recommend checking out some of the top attractions.

Savor the day by heading to Piazzale Michelangelo, a top-rated observation deck that draws visitors from near and far. When you're done, continue to Uffizi Gallery, where you can soak in the eye-catching surroundings.

Next, explore Ponte Vecchio, yet another iconic place to see in the area. After the historical landmark, make time to go to Cathedral Of Santa Maria Del Fiore. This culturally significant church is well worth the visit. Lastly, head to Piazza Della Signoria, a top-rated public square you won’t want to miss.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor the flavors at Ristorante Oliviero 1962, a top pick for dinner tonight. Alternatively, Di Poneta Novoli beckons with its unique menu offerings. Also, consider Caffe San Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

After your meal, keep the night alive at a bar like Manifattura, known for its lively atmosphere. Se·sto On Arno Rooftop Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Il Vinile offers an excellent atmosphere for those looking to amp up the evening.

Relax and recharge in preparation for another adventurous day in Italy!