6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina

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Photo of Palermo City, Sicily island in Italy. Aerial view of beautiful Mediterranean town. Drone Photography.
Photo of Palermo, Sicily, Italy. Seafront view.
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
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Escape the ordinary with this exciting 6-day road trip through Sicily. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 2 nights in Palermo, 1 night in Agrigento, and 2 nights in Taormina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Palermo, Agrigento, Piazza Armerina, Taormina, Catania, and Cefalù, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Say hello to Palermo! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Palermo for 1 night before you continue your adventure!

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Palermo. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Cotto e Bollito, an iconic dining spot in Palermo. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bebop, a popular restaurant in Palermo. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eremiti Restaurant, a hidden gem nestled in Palermo. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your lively evening at Malox Cult, a perfect place for winding down or revving up the night, depending on which mood you’re in. Ai Giudici is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bar Italico ensures a night out tailored to your taste.

Raise a toast to the start of your 6-day road trip in Sicily!

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Day2

Day 2

  • Palermo
  • Agrigento
  • More

Drive 138 km, 2 hours 53 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Orto botanico di Palermo
  • Valle dei Templi
  • More

On day 2 of your road trip in Sicily, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Palermo and Agrigento are on today's agenda. In the evening, you’ll end up in Agrigento, where you will stay for 1 night.

Norman Palace is perfect for a self-paced visit during the day. This picture-perfect palace is sure to impress. Next on your list is Palermo Cathedral, another must-visit landmark and interesting church renowned for its monumental features.

While exploring and sightseeing, take time to savor the culture of Palermo by sampling some local delicacies. When you’re ready for more sightseeing, head to Quattro Canti. This history-steeped public square is an essential place to visit for anyone looking for the full Palermo experience. We also recommend visiting Fontana Pretoria, an up-and-coming monument. Nearby, you'll also find Orto Botanico Di Palermo, ready to add charm to your journey.

Agrigento’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Palermo behind. This drive usually takes around 1 hour 59 min. Agrigento welcomes you with a multitude of unique vacation experiences.

For a more meaningful self-guided tour of the city's best attractions, visit Valle Dei Templi, a captivating archeological site that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Agrigento. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Agrigento's most popular restaurants, and connect with friendly locals for a true cultural experience.

Dine in style at Ambasciata di Sicilia, a top recommendation for dinner tonight. Or, for a change of pace, Le Cuspidi boasts a menu that's sure to impress. Also, be sure to check out Yellove RistoVintage. Known as a local hotspot, it’s a great choice for tonight in Agrigento.

Take some time to reflect on your day and savor another beautiful night in Sicily.

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Day3

Day 3

  • Agrigento
  • Piazza Armerina
  • Taormina
  • More

Drive 248 km, 4 hours 17 min

  • Villa Romana del Casale
  • Isola Bella
  • Villa Comunale di Taormina
  • Ancient theatre of Taormina
  • Porta Catania
  • More

Experience an unparalleled adventure on day 3 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Piazza Armerina, Mazzarò, and Taormina. At the end of the day, you will retreat to the hotel of your choice in Taormina, where will spend 2 nights.

Piazza Armerina’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Agrigento behind. This drive usually takes around 1 hour 23 min. Piazza Armerina welcomes you with a multitude of unique vacation experiences.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Villa Romana Del Casale, a popular archeological site that everyone visiting Piazza Armerina should see.

When you’ve had your share of Piazza Armerina, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Mazzarò. Your travel time is around 1 hour 53 min.

One of our top recommendations for your sightseeing is Isola Bella. Then, head to Ancient Theatre Of Taormina. This popular archeological site is a traveler-favorite in the town.

Upon reaching Taormina, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Set out on a self-guided sightseeing tour at Villa Comunale Di Taormina and explore the serene features. Next, make your way to Porta Catania, another highlight in Taormina.

At the end of the day, you will drive to Taormina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Taormina. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely dining experience at PizzaMania Taormina, a popular restaurant in Taormina. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Taormina at Ristorante Pizzeria Tiramisù Taormina, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated La Pignolata Guinness Cannoli Taormina {since 1978} N°15. It’s yet another ideal choice to enhance your time in Taormina tonight.

Unwind after your meal by stepping into Luraleo Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Don Diego Gelateria Caffetteria offers a dynamic and energetic atmosphere for a glass or two.

Head back to your accommodation in Taormina and get some rest to prepare for another magical day of your road trip in Sicily.

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Day4

Day 4

  • Taormina
  • Catania
  • More

Drive 108 km, 1 hour 59 min

  • Castello Ursino
  • Greek - Roman theatre
  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • Piazza Università
  • Villa Bellini/Chiosco Bellini
  • More

On day 4 of your road trip in Sicily, you’ll start and end your day in Taormina, but spend the day exploring what’s beyond the town. Since you still have 1 night to spend in Taormina, there’s no need to rush. Experience Catania to the fullest today with this curated day itinerary.

When you’ve had your share of Taormina, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Catania. Your travel time is around 50 min.

For a more meaningful self-guided tour of the city's best attractions, visit Castello Ursino, a locally renowned castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Roman Theatre Of Catania and admire its stunning features.

When you’re ready, continue to Elephant Fountain, a locally appreciated monument beloved by locals and tourists alike. Don't miss out on Catania Cathedral, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Piazza Università, a history-steeped place to see that you won’t regret spending some extra time discovering.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Taormina.

After a day of adventure, treat yourself to an exquisite dinner at one of Taormina's best restaurants.

Enjoy a lovely dining experience at Osteria Il Vicoletto, a popular restaurant in Taormina. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Taormina at Tischi Toschi Taormina, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Siciliano Taormina Osteria Pizzeria. It’s yet another ideal choice to enhance your time in Taormina tonight.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Sicily.

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Day5

Day 5

  • Taormina
  • Cefalù
  • Palermo
  • More

Drive 281 km, 3 hours 58 min

  • Rocca di Cefalù
  • Cathedral of Cefalù
  • Porta della Pescara (Porta Marina)
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • Cefalù Beach
  • More

On day 5 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 1 destination, including Cefalù. When you’re not sightseeing, take time to relax at your chosen hotel in Palermo, where you’ll be staying for 1 night.

After soaking in Taormina’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Cefalù. Expect your car journey to take a minimum of 2 hours 44 min. When you arrive in Cefalù, it's time to take a break from the road.

Spend your afternoon discovering Rocca Di Cefalù, an up-and-coming castle known for its history-steeped features. Next, continue your sightseeing at Cefalù Cathedral, a locally renowned church.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Porta Pescara (porta Marina) and uncover the details of this history-steeped historical landmark. Make sure to also explore Lavatoio Medievale Fiume Cefalino - Cefalù (pa), an intriguing historical landmark. For your last stop, consider Spiaggia Di Cefalù, an eye-catching beach that many travelers find worth the detour.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Palermo. Palermo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Palermo's best restaurants.

Treat yourself to a delicious dinner at Osteria Mercede, an excellent option for tonight's dining. Looking for something different? Trattoria Del Massimo offers a tantalizing alternative with its diverse menu. And don’t miss Grand Hotel Piazza Borsa. Known for great service, it’s a fantastic choice for tonight in Palermo.

Cap off your dinner by heading to Spina Bar Palermo, ideal for a leisurely evening with a drink in hand. Torrefazione Castagnetta Massimiliano (gelateria) is another bar that offers an enjoyable setting. Similarly, Monkey Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass and celebrate another amazing day of your road trip in Sicily!

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Day6

Day 6

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
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Day 6 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Catacombe Dei Cappuccini, a photogenic cemetery before you head out.

Take advantage of your accommodation's proximity to Palermo’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

If you're eager to try something different, consider Ristorantino Sobremesa, another top spot with a tantalizing menu.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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