6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina

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Photo of Palermo City, Sicily island in Italy. Aerial view of beautiful Mediterranean town. Drone Photography.
Photo of Palermo, Sicily, Italy. Seafront view.
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
6-Day Sicily Self-Drive Road Trip With Itinerary from Palermo traveling east to Agrigento and Taormina
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Escape the ordinary with this exciting 6-day road trip through Sicily. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 2 nights in Palermo, 1 night in Agrigento, and 2 nights in Taormina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Palermo, Agrigento, Piazza Armerina, Taormina, Catania, and Cefalù, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Palermo - Arrival day
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  • Foro Italico
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Welcome to Palermo, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night discovering what to see in Palermo before embarking on the next leg of your journey.

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Palermo. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Savor the flavors at Cotto e Bollito, a top pick for dinner tonight. Alternatively, Bebop beckons with its unique menu offerings. Also, consider Eremiti Restaurant. With its consistent customer satisfaction, it’s an excellent option for dining in Palermo tonight.

After your meal, keep the night alive at a bar like Malox Cult, known for its lively atmosphere. Ai Giudici is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Italico offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 6-day road trip in Sicily!

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Day2

Day 2

  • Palermo
  • Agrigento
  • More

Drive 138 km, 2 hours 53 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Orto botanico di Palermo
  • Valle dei Templi
  • More

On day 2 of your road trip in Sicily, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Palermo and Agrigento are on today's agenda. In the evening, you’ll end up in Agrigento, where you will stay for 1 night.

Let Norman Palace set the tone for the day. Spend some time admiring this picture-perfect palace before continuing your journey. Palermo Cathedral is your next stop. This notable church is one of the best-rated sights in Palermo.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Quattro Canti. This symbolic public square is a sight to behold. To round off your sightseeing experience, visit Fontana Pretoria and Orto Botanico Di Palermo.

When you’re ready to jump back into the car and say goodbye to Palermo, you’ll hit the road in the direction of Agrigento. This drive usually takes around 1 hour 59 min.

Spend your afternoon discovering Valle Dei Templi, a popular archeological site known for its picture-perfect features.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Agrigento. Agrigento offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Agrigento's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Ambasciata di Sicilia, a highly-rated dining destination in Agrigento. If you're eager to try something different, consider Le Cuspidi, another top spot with a tantalizing menu. You might also want to secure a reservation at Yellove RistoVintage. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Agrigento this evening.

Head back to your accommodation in Agrigento and get some rest to prepare for another magical day of your road trip in Sicily.

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Day3

Day 3

  • Agrigento
  • Piazza Armerina
  • Taormina
  • More

Drive 248 km, 4 hours 17 min

  • Villa Romana del Casale
  • Isola Bella
  • Villa Comunale di Taormina
  • Ancient theatre of Taormina
  • Porta Catania
  • More

Your itinerary for day 3 of your road trip in Sicily includes 3 stops and features some of the highlights of Piazza Armerina, Mazzarò, and Taormina. At the end of the day, enjoy the comforts of a top-rated hotel in Taormina, where you'll spend 2 nights.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Piazza Armerina. This drive usually takes around 1 hour 23 min, without any stops or traffic disruptions.

Set out on a self-guided sightseeing tour at Villa Romana Del Casale and explore the breathtaking features.

Continue your road trip and head to your next destination, Mazzarò. This car ride takes around 1 hour 53 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Isola Bella, a curiosity-inducing park that everyone visiting Mazzarò should see. Next, head to Ancient Theatre Of Taormina. This history-steeped archeological site is one of the most notable attractions in the region.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Taormina.

For a more meaningful self-guided tour of the town's best attractions, visit Villa Comunale Di Taormina, an up-and-coming park that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Porta Catania and admire its eye-catching features.

When you’re done exploring for the day, you’ll drive to your hotel in Taormina. Check in and relax before you head out to tour the town.

After a day of adventure, treat yourself to an exquisite dinner at one of Taormina's best restaurants.

Treat yourself to a delightful dinner at PizzaMania Taormina, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Pizzeria Tiramisù Taormina? It's another excellent option with a diverse menu. Consider reserving a table at La Pignolata Guinness Cannoli Taormina {since 1978} N°15 as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Taormina.

Let the evening flow smoothly from dinner to drinks at Luraleo Bar, a top-rated bar in the area. For other recommendations, Don Diego Gelateria Caffetteria provides a perfect setting for rounding out your night with style and great drinks.

Raise your glass and celebrate another amazing day of your road trip in Sicily!

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Day4

Day 4

  • Taormina
  • Catania
  • More

Drive 108 km, 1 hour 59 min

  • Castello Ursino
  • Greek - Roman theatre
  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • Piazza Università
  • Villa Bellini/Chiosco Bellini
  • More

Wake up to day 4 of your road trip in Sicily. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Catania. With 1 night to stay in Taormina, we encourage you to seize the day and discover the unexplored beauty of the town’s surroundings!

Catania is brimming with adventures.

When you’ve had your share of Taormina, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Catania. Your travel time is around 50 min.

Castello Ursino is an interesting castle we recommend visiting today. Discover its photogenic features before continuing your self-guided tour to Roman Theatre Of Catania, a historic archeological site that’s well-regarded in the area.

Next, stop by Elephant Fountain, a symbolic monument. While you’re nearby, don’t forget to visit Catania Cathedral, a history-steeped and truly unique church. End your sightseeing at Piazza Università, a worthwhile public square that’s highly recommended by travelers passing through the city.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Taormina.

After a day of adventure, treat yourself to an exquisite dinner at one of Taormina's best restaurants.

Enjoy a delicious meal at Osteria Il Vicoletto, a highly-rated dining destination in Taormina. If you're eager to try something different, consider Tischi Toschi Taormina, another top spot with a tantalizing menu. You might also want to secure a reservation at Siciliano Taormina Osteria Pizzeria. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Taormina this evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Sicily.

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Day5

Day 5

  • Taormina
  • Cefalù
  • Palermo
  • More

Drive 281 km, 3 hours 58 min

  • Rocca di Cefalù
  • Cathedral of Cefalù
  • Porta della Pescara (Porta Marina)
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • Cefalù Beach
  • More

Dive into day 5 of your remarkable road trip in Sicily. Today you'll explore 1 destination, including Cefalù. At the end of the day, you’ll unwind at one of the finest accommodations in Palermo, where you'll spend 1 night.

Set your GPS to Cefalù and hit the road. Expect a journey of approximately 2 hours 44 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Cefalù beckons with new experiences!

For a more meaningful self-guided tour of the town's best attractions, visit Rocca Di Cefalù, a curiosity-inducing castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Cefalù Cathedral and admire its symbolic features.

When you’re ready, continue to Porta Pescara (porta Marina), a beloved historical landmark beloved by locals and tourists alike. Don't miss out on Lavatoio Medievale Fiume Cefalino - Cefalù (pa), another highlight of the area that promises a memorable visit. Not far away, you’ll also find Spiaggia Di Cefalù, an instagrammable place to see that you won’t regret spending some extra time discovering.

At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Palermo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Osteria Mercede, a top recommendation for dinner tonight. Or, for a change of pace, Trattoria Del Massimo boasts a menu that's sure to impress. Also, be sure to check out Grand Hotel Piazza Borsa. Known as a local hotspot, it’s a great choice for tonight in Palermo.

Explore the vibrant nightlife at Spina Bar Palermo after your meal, a hub for lively evenings and memorable moments. Or, head to Torrefazione Castagnetta Massimiliano (gelateria) for a great selection of flavorful drinks and a charming setting. Furthermore, Monkey Pub is perfect for those looking to extend their night with a touch of local flavor.

Savor another day of unforgettable experiences in Sicily!

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Day6

Day 6

  • Palermo - Departure day
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  • Catacombe dei Cappuccini
  • More

Day 6 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Catacombe Dei Cappuccini. This captivating cemetery is a hotspot among locals.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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