5-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence

Your itinerary for day 2 of your road trip in Italy includes 2 stops and features some of the highlights of Rome and Florence. At the end of the day, enjoy the comforts of a top-rated hotel in Florence, where you'll spend 2 nights.

Roman Forum brings Rome's character to life. This breathtaking archeological site is a highlight of any visit in the city. Then, enjoy Colosseum, another picture-perfect attraction that never fails to captivate visitors. Next, head over to Trevi Fountain, one of the city’s most timeless attractions, known for its visually striking features.

If you’re looking for more, spend time soaking in the atmosphere of Spanish Steps. This enchanting public square is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

When you’ve had your share of Rome, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Florence. Your travel time is around 3 hours 4 min.

One of our top recommendations for your sightseeing is Cathedral Of Santa Maria Del Fiore. Spend some time admiring the inviting features of the church before you continue to your next stop.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor the flavors at Ristorante Oliviero 1962, a top pick for dinner tonight. Alternatively, Di Poneta Novoli beckons with its unique menu offerings. Also, consider Caffe San Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Continue the enjoyment post-dinner at Manifattura, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Se·sto On Arno Rooftop Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Il Vinile. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 3 of your road trip, you'll get the chance to experience Florence, Pisa, and Lucca. At the end of the day, you'll drive back to Florence, where you still have 1 night left to stay.

Ponte Vecchio is perfect for a self-paced visit during the day. This history-steeped historical landmark is sure to impress. Next on your list is Uffizi Gallery, another must-visit landmark and top-rated art gallery renowned for its picture-perfect features.

While exploring and sightseeing, take time to savor the culture of Florence by sampling some local delicacies. When you’re ready for more sightseeing, head to Piazzale Michelangelo. This visually striking observation deck is an essential place to visit for anyone looking for the full Florence experience.

Embrace the thrill of the open road as you wave goodbye to Florence and set your GPS to Pisa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 16 min. Upon reaching Pisa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Savor the day by heading to Piazza Del Duomo, Pisa, a wondrous public square that draws visitors from near and far. When you're done, continue to Leaning Tower Of Pisa, where you can soak in the historic surroundings.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Lucca may take around 28 min. Upon your arrival in Lucca, you’ll be greeted with the opportunity to do some sightseeing and exploring.

When you're ready for some sights, head to Porta San Pietro, an increasingly popular monument in Lucca. Explore its culturally significant features at your own pace before you continue your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a wonderful meal at Ditta Artigianale, a top-rated dining spot in Florence. If you're in the mood for something new, try Trattoria Da Burde, another premier location with a delectable menu. You might also want to book a table at Casa Toscana. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Let the evening flow smoothly from dinner to drinks at Bar 50 Rosso, a top-rated bar in the area. For other recommendations, Bitter Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Archea Brewery offers a memorable night with diverse drink options and excellent service.

Get a good night's sleep and look forward to another great day on the road in Italy!

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Siena and San Gimignano. At the end of the day, you will retreat to the hotel of your choice in Rome, where will spend 1 night.

Set your GPS to Siena and hit the road. Expect a journey of approximately 1 hour 10 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Siena beckons with new experiences!

Fortezza Medicea (siena) is a frequently visited monument we recommend visiting today. Discover its picture-perfect features before continuing your self-guided tour to Piazza Del Campo, an UNESCO world heritage-listed public square that’s well-regarded in the area.

Next, stop by Siena Cathedral, an inviting church.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to San Gimignano may take around 46 min. Upon your arrival in San Gimignano, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Savor the day by heading to Piazza Del Duomo, a beloved public square that draws visitors from near and far.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at RomAntica, an excellent option for tonight's dining. Looking for something different? Coso Ristorante offers a tantalizing alternative with its diverse menu. And don’t miss DEROMA - Farine Romane. Known for great service, it’s a fantastic choice for tonight in Rome.

Continue your lively evening at Sant' Eustachio Caffè, a perfect place for winding down or revving up the night, depending on which mood you’re in. Yellowsquare Rome is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Caffè Portofino ensures a night out tailored to your taste.

Say good night to Rome and look forward to another great day of your road trip in Italy!