5-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento and surrounding area

On day 2 of your road trip, you will have an entire day to discover what to see in Palermo. You’ll stay in Palermo for 1 night.

One of the most intriguing attractions included on the itinerary is Fontana Pretoria. This romantic monument will help you start your sightseeing on top. Then, take a leisurely stroll to Quattro Canti and learn what makes this grand public square unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the increasingly popular Martorana. After exploring the church, head to Riserva Naturale Di Capo Gallo. This underrated nature reserve is a highlight in Palermo. As your day continues, stop by Santuario Di Santa Rosalia, Palermo, known for its majestic features.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Sicily. You can explore and select activities under each day of your itinerary.

Palermo is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Palermo.

Enjoy an outstanding dining experience at Buatta Cucina Popolana, a Bib Gourmand restaurant offering an exceptional sicilian menu. Alternatively, if you're in the mood for something different, consider the nearby 1-star Michelin-awardee, Mec Restaurant, known for its delicious sicilian and contemporary cuisine. Another highly-recommended place to eat in Palermo is Gagini Restaurant, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious creative and contemporary menu.

Keep the evening going at Spina Bar Palermo, a great choice for enjoying the after-dinner hours with a drink. You could also go to Torrefazione Castagnetta Massimiliano (gelateria), which offers a similarly pleasant setting and great drinks. Another option is Monkey Pub, which provides an inviting environment for unwinding after a busy day out.

Raise your glass to another unforgettable day in Sicily!

Your itinerary for day 3 of your road trip in Sicily includes 1 stop and features some of the highlights of Palermo. At the end of the day, enjoy the comforts of a top-rated hotel in Agrigento, where you'll spend 1 night.

Norman Palace leaves a lasting impression. This palace is one of the most locally renowned places to visit in Palermo. Next, head to Palermo Cathedral, a locally renowned church, known for its historic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Orto Botanico Di Palermo. This serene botanical garden is a highly recommended experience. Nearby, you'll also find Catacombe Dei Cappuccini Visit these for an interesting touch to your journey.

At the end of the day, you will drive to Agrigento, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Agrigento's best restaurants.

Treat yourself to a delicious dinner at Ambasciata di Sicilia, an excellent option for tonight's dining. Looking for something different? Le Cuspidi offers a tantalizing alternative with its diverse menu. And don’t miss Yellove RistoVintage. Known for great service, it’s a fantastic choice for tonight in Agrigento.

Relax and recharge in preparation for another adventurous day in Sicily!

Dive into day 4 of your remarkable road trip in Sicily. Today you'll explore 3 destinations, including Xitta, San Vito Lo Capo, and Castellammare del Golfo. At the end of the day, you’ll unwind at one of the finest accommodations in Palermo, where you'll spend 1 night.

Xitta’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Agrigento behind. This drive usually takes around 2 hours 8 min. Xitta welcomes you with a multitude of unique vacation experiences.

Set out on a self-guided sightseeing tour at Saline Di Trapani E Paceco and explore the romantic features.

Embrace the thrill of the open road as you wave goodbye to Xitta and set your GPS to San Vito Lo Capo. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 47 min. Upon reaching San Vito Lo Capo, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

When you're ready for some sights, head to Riserva Naturale Orientata Dello Zingaro, Ingresso Sud, an up-and-coming nature reserve in San Vito Lo Capo. Explore its mesmerizing features at your own pace before you continue your journey.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Castellammare del Golfo may take around 24 min. Upon your arrival in Castellammare del Golfo, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Savor the day by heading to Belvedere Castellammare Del Golfo, a curiosity-inducing observation deck that draws visitors from near and far. When you're done, continue to Marina Di Castellammare Del Golfo, where you can soak in the eye-catching surroundings.

When you’re done exploring for the day, you’ll drive to your hotel in Palermo. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Palermo. Enjoy a relaxing evening as you savor delicious local cuisine.

Don’t miss out on dining at Splendid Hotel la Torre, a top-rated dining destination in Palermo. If you're in the mood to try something new, consider Ristorantino Sobremesa, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Quattro mani. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Palermo this evening.

Following your dinner, dive into the local bar culture at Bar Touring. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Palermo Football Store, the perfect place for those looking to experience the best of the nightlife. Similarly, Goccio - L’arte Del Miscelare provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise your glass and celebrate another amazing day of your road trip in Sicily!