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3-Day Italy Self-Drive Road Trip With Itinerary Starting in Brindisi

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.

3-Day Italy Self-Drive Road Trip With Itinerary Starting in Brindisi

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Explore the best of Italy on a remarkable 3-day road trip! Combine exploration with relaxation on a self-drive tour featuring Brindisi, Matera, and Alberobello.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Brindisi. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Sassi Di Matera and Trulli Di Alberobello Puglia are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Brindisi, Matera, and Alberobello, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65

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Day1

Day 1

Brindisi - Arrival day
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Lungomare Regina Margherita
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Your road trip adventure in Italy begins as soon as you reach Brindisi and pick up your car. You’ll stay here for 2 nights and explore what to see in Brindisi, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Amici Dei Musei Brindisi. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Brindisi. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Bracerie Escosazio, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Penny? It's another excellent option with a diverse menu. Consider reserving a table at Piadineria as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Brindisi.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse stands out as an excellent choice for a post-dinner cocktail. Alternatively, Eden Cafè offers an ideal atmosphere to enjoy the pleasures of the night. Altair Cafè is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 3-day road trip in Italy!

Day2

Day 2

Brindisi
Matera
Alberobello
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Drive 304 km, 4 hours 32 min

Palombaro lungo
Sassi di Matera
Belvedere di Piazza Giovanni Pascoli
Trulli di Alberobello Puglia
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On day 2 of your road trip, you’ll start and end your day in Brindisi, where you have 1 night left to stay.

Matera’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Brindisi behind. This drive usually takes around 1 hour 54 min. Matera welcomes you with a multitude of unique vacation experiences.

Palombaro Lungo is a frequently visited cave system we recommend visiting today. Discover its heritage-rich features before continuing your self-guided tour to Sassi Di Matera, an awe-inspiring archeological site that’s well-regarded in the area.

Next, stop by Belvedere Di Piazza Giovanni Pascoli, a gorgeous observation deck.

When you’ve had your share of Matera, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Alberobello. Your travel time is around 1 hour 8 min.

Set out on a self-guided sightseeing tour at Trulli Di Alberobello Puglia and explore the romantic features.

When you’re done exploring for the day, you’ll return to Brindisi and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Brindisi's best restaurants.

Have a fantastic dining experience at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bento offers an enticing alternative with its varied menu. Additionally, Cozza Nera is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Brindisi.

Say good night to Brindisi and look forward to another great day of your road trip in Italy!

Day3

Day 3

Brindisi - Departure day
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Palazzo Granafei Nervegna (Brindisi)
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Day 3 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Palazzo Granafei Nervegna (brindisi). This underrated palace is a hotspot among locals.

Make the most of your final day in Italy by visiting Brindisi’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

Treat yourself to a delightful dinner at Rendez-Vous Cafè Bistrot, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Pizzeria La Nassa? It's another excellent option with a diverse menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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