Two-Week Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Genoa, Pisa, Viterbo, Naples, Rome, and Perugia

On day 2 of your road trip, you will have an entire day to discover what to see in Florence. You’ll stay in Florence for 1 night.

Florence is brimming with adventures.

Make time for Basilica Of Santa Croce In Florence, a well-known church that is worthwhile a visit in the city. Nearby, you’ll find Piazza Della Signoria, enchanting visitors with its romantic appeal. Continue your exploration at Uffizi Gallery. This art gallery is one of the city’s most impressive spots.

Enjoy the freedom of exploring Florence at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Ponte Vecchio. After exploring the historical landmark, head to the locally renowned The Boboli Gardens.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Bring home unique finds from Florence's bustling shopping hub, San Lorenzo Market. Enjoy a leisurely exploration of unique stores where locals shop. Don’t forget to browse souvenirs and local specialties that make perfect gifts for your loved ones. Beyond shopping, San Lorenzo Market offers plenty of options, including primary services, unique landmarks, and community events.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Begin your culinary exploration in Florence by securing a reservation at Enoteca Pinchiorri. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another dining delight, visit Santa Elisabetta, celebrated for its delectable creative and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Gucci Osteria da Massimo Bottura, a top local spot known for its tantalizing italian contemporary and international menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 3 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Genoa, where you will stay for 1 night.

Look forward to a unique sightseeing adventure at the extraordinary Cathedral Of Santa Maria Del Fiore and allow yourself time to explore.

Continue your journey to Galleria Dell'accademia, one of the city’s most captivating spots that you shouldn’t miss. Another great site to visit is the captivating Basilica Di Santa Maria Novella, Firenze (fi).

At the end of the day, you will drive to Genoa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine.

Experience a taste of local culinary excellence while in Genoa by securing a table at San Giorgio. An esteemed 1-star Michelin restaurant, it features an exceptional modern and ligurian menu. For an alternative taste experience, visit The Cook, famous for its scrumptious modern dishes. This 1-star Michelin venue consistently impresses guests, making it a standout addition to your holiday plans. Looking for another choice? Discover Il Marin, a local favorite celebrated for its exquisite seafood and contemporary cuisine in Genoa. Located in the heart of the city, this 1-star Michelin restaurant is an ideal pick for seafood and contemporary cuisine lovers seeking top-notch culinary experiences.

To truly maximize your evening out, consider visiting Scurreria Beer & Bagel after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to La Lepre, another bar with an inviting ambiance. Similarly, Bar Pisacane Iii also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Take some time to reflect on your day and savor another beautiful night in Italy.

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Genoa and Corniglia. At the end of the day, you’ll unwind at one of the finest accommodations in Pisa, where you'll spend 1 night.

One of the most interesting attractions included on the itinerary is Piazza De Ferrari. This grand public square will help you start your sightseeing on top. Then, take a leisurely stroll to Aquarium Of Genoa and learn what makes this mesmerizing aquarium unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the popular Porto Antico.

Fasten your seatbelt and make your way to your next stop — Corniglia, home to many well-known sights in the region. Keep in mind that your travel time from Genoa to Corniglia may take around 1 hour 42 min without traffic disruptions. Upon arrival in Corniglia, we highly recommend checking out some of the top attractions.

Our first attraction recommendation in Corniglia is Cinque Terre National Park, an interesting national park that draws attention for its eye-catching features.

When you’re done exploring for the day, you’ll drive to your hotel in Pisa. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Pisa, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Anima di Grano Pizzeria Napoletana Pisa Italy, a highly-rated dining destination in Pisa. If you're eager to try something different, consider il Mercante, another top spot with a tantalizing menu. You might also want to secure a reservation at La Ghiotteria. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Pisa this evening.

After savoring a delicious meal, step into the vibrant nightlife at Jeffer Cocktails & Friends, where the evening is just getting started. In the same way, Le Parisien Wine Bar offers a unique charm perfect for experiencing the local bar scene in Pisa. Las Volta Cocktailbar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass to another unforgettable day in Italy!

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Pisa. At the end of the day, you will retreat to the hotel of your choice in Viterbo, where will spend 1 night.

Whatever your travel style is, Knights' Square is an essential stop in Pisa. This increasingly popular public square provides an insightful glimpse into the city's identity. Next, discover Leaning Tower Of Pisa, a picture-perfect monument, promising a delightful encounter.

Continue your sightseeing with a visit to Piazza Del Duomo, Pisa, a globally renowned public square. When you’re done, don’t forget to make a stop at the worthwhile Pisa Cathedral.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Viterbo. Viterbo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Viterbo's most popular restaurants, and connect with friendly locals for a true cultural experience.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Your itinerary for day 6 of your road trip in Italy includes 2 stops and features some of the highlights of Caserta and San Leucio-complex. At the end of the day, enjoy the comforts of a top-rated hotel in Naples, where you'll spend 2 nights.

Caserta’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Viterbo behind. This drive usually takes around 2 hours 46 min. Caserta welcomes you with a multitude of unique vacation experiences.

When you're ready for some sights, head to Fontana Margherita, a curiosity-inducing park in Caserta. This interesting park is a top recommendation in the area.

When you’re ready to explore more, Palace Of Caserta is an excellent choice. Spend some time discovering what some claim to be the most enchanting palace in the region.

Continue your road trip and head to your next destination, San Leucio-complex.

Savor the day by heading to English Garden, an increasingly popular botanical garden that draws visitors from near and far.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Begin your culinary exploration in Naples by securing a reservation at Veritas. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of campanian and contemporary cuisine. For another dining delight, visit Il Comandante, celebrated for its delectable creative and mediterranean menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover ARIA, a top local spot known for its tantalizing contemporary and modern menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

Keep the excitement of the evening going by visiting a bar or two. Happening Cocktail Bar is an excellent place to start. You could also check out Shanti Art Musik Bar, offering a different kind of charm. A last recommendation for the day is Gran Caffè Gambrinus. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Say good night to Naples and look forward to another great day of your road trip in Italy!

On day 7 of your road trip, you'll get the chance to experience Ravello, Amalfi, and Pompei. At the end of the day, you'll drive back to Naples, where you still have 1 night left to stay.

Ravello’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Naples behind. This drive usually takes around 1 hour 10 min. Ravello welcomes you with a multitude of unique vacation experiences.

For a more meaningful self-guided tour of the village's best attractions, visit Villa Rufolo, a popular historical landmark that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’ve had your share of Ravello, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Amalfi. Your travel time is around 20 min.

Amalfi Coast is a widely recognized coast we recommend visiting today.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Pompei may take around 1 hour 3 min. Upon your arrival in Pompei, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Our first attraction recommendation in Pompei is Archaeological Park Of Pompeii, a captivating archeological site that draws attention for its UNESCO world heritage-listed features. Spend some time soaking in the atmosphere before continuing to Teatro Grande, a standout archeological site that stands out in the village.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Amphitheatre Of Pompeii, a captivating archeological site that offers a unique experience.

When you’re done exploring for the day, you’ll return to Naples and your accommodation.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for a true cultural experience.

Dine in style at Antica Pizzeria Di Matteo, a top recommendation for dinner tonight. Or, for a change of pace, Mercure Napoli Centro Angioino boasts a menu that's sure to impress. Also, be sure to check out La Lazzara Trattoria e Pizzeria. Known as a local hotspot, it’s a great choice for tonight in Naples.

Continue the enjoyment post-dinner at Archivio Storico - Cocktail Bar & Wonderfood, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Archeobar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Babette Pub. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 8 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Naples. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 5 nights.

Piazza Del Plebiscito leaves a lasting impression. This public square is one of the most spectacular places to visit in Naples. Next, head to Ovo Castle, a locally renowned castle, known for its visually striking features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Naples National Archaeological Museum. This heritage-rich museum is a highly recommended experience. Nearby, you'll also find Cappella Sansevero Visit these for an interesting touch to your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Experience a symphony of flavors at La Pergola in Rome by securing a reservation in advance. Renowned for its 3-star Michelin distinction, La Pergola delights its guests with its exceptional variety of meals showcasing delicious mediterranean and contemporary cuisine. For a palate-pleasing alternative, make sure to dine at Il Pagliaccio, acclaimed for its delectable creative and innovative specialties. This local 2-star Michelin establishment consistently satisfies guests, ensuring an unforgettable holiday experience. Want to go on another culinary journey? Delight your senses at Enoteca La Torre, a top-rated restaurant known for its outstanding menu. Known as a top-rated 2-star Michelin establishment, it's a top choice for mediterranean and creative cuisine in the city.

Continue the enjoyment post-dinner at La Botticella Of Poggi Giovanni, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Almalu Trastevere offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Bar Viminale Di Pepi Maurilio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Celebrate another amazing day of your road trip adventure in Italy!

Day 9 offers an itinerary packed with the best things to see in Florence. You’ll stay in Rome for 4 nights more, offering you enough time to explore at a relaxed pace.

Archbasilica Of St. John Lateran is must-visit church and a great option for a daytime tour of the area. Continue your journey to Basilica Di Santa Maria Maggiore, a well-known church, located just a leisurely stroll away. Next, head to Trevi Fountain, a visually striking monument, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Rome. When you're ready, let your sightseeing route take you to the timeless Piazza Di Spagna. If you’re looking for more, Spanish Steps is also an extraordinary attraction that is worthwhile a visit.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delicious dinner at RomAntica, an excellent option for tonight's dining. Looking for something different? Coso Ristorante offers a tantalizing alternative with its diverse menu. And don’t miss DEROMA - Farine Romane. Known for great service, it’s a fantastic choice for tonight in Rome.

Unwind after your meal by stepping into Sant' Eustachio Caffè. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Yellowsquare Rome offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffè Portofino, another top-rated bar in the area.

Relax and look forward to more memorable moments to come!

Day 10 of your road trip will take you to the best attractions Rome has to offer. Cherish the 3 nights you have left in the city and use the provided itinerary to discover what to see in Rome.

Your adventure in Rome is only getting started when you visit Castel Sant'angelo, a famous local hot spot. Another notable attraction to explore is Campo De' Fiori. This famous public square is known for its romantic appeal.

After soaking in the highlights of these sights, take some time to wander Rome's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Piazza Navona. This enchanting public square offers a fascinating experience that many visitors find memorable. Pantheon is also worth visiting, along with Largo Di Torre Argentina. These standout landmarks offer unique experiences that add to the day’s enjoyment.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like The Apartment Bar Roma, known for its lively atmosphere. Hotel Hassler Roma is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance.

Raise your glass to another unforgettable day in Italy!

Day 11 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Foro Italico brings Rome's character to life. This eye-catching sports complex is a highlight of any visit in the city. Then, enjoy Belvedere Del Gianicolo, another romantic attraction that never fails to captivate visitors. Next, head over to Piazza Del Popolo, one of the city’s most widely recognized attractions, known for its enchanting features.

If you’re looking for more, spend time soaking in the atmosphere of Villa Borghese. This standout park is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Auditorium Parco Della Musica, a well-known concert hall, and take a stroll around the area.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Have a fantastic dining experience at Sofitel Roma Villa Borghese, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Centro offers an enticing alternative with its varied menu. Additionally, Ristorante Tema is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

Relax and recharge in preparation for another adventurous day in Italy!

On day 12 of your road trip, you will have an entire day to discover what to see in Rome. You’ll stay in Rome for 1 night.

Make a stop at Altare Della Patria. This locally renowned monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Capitoline Hill located in Rome for another exciting encounter.

Next, immerse yourself in the setting of Roman Forum. Its UNESCO world heritage-listed features will captivate you. After the archeological site, continue your tour of the city with a visit to Colosseum. Visitors usually appreciate the UNESCO world heritage-designated features of this archeological site. Next up is Circus Maximus, a highly recommended archeological site.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely dining experience at Ristorante Va. Do. , a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Giulia Restaurant, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated L'Archeologia. It’s yet another ideal choice to enhance your time in Rome tonight.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 13 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Vatican City are on today's agenda. In the evening, you’ll end up in Perugia, where you will stay for 1 night.

Continue your road trip and head to your next destination, Vatican City, Vatican City. This car ride takes around 11 min.

For a more meaningful self-guided tour of the city's best attractions, visit St. Peter's Basilica, a timeless major basilica that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re ready, continue to Saint Peter's Square, a popular square beloved by locals and tourists alike. Don't miss out on Vatican Museums, another highlight of the area that promises a memorable visit.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Perugia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Ristorante Settimo Sigillo, a top-rated dining destination in Perugia. If you're in the mood to try something new, consider Caffè Baglioni, another top spot with a mouthwatering menu. You might also want to secure a reservation at Bar Pellas. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Perugia this evening.

Keep the evening going at Tommi Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Valentina, which offers a similarly pleasant setting and great drinks. Another option is Caffe Dal Perugino, which provides an inviting environment for unwinding after a busy day out.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Dive into day 14 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Santa Maria degli Angeli. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 1 night.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Santa Maria degli Angeli may take around 32 min. Upon your arrival in Santa Maria degli Angeli, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Set out on a self-guided sightseeing tour at Basilica Of San Francesco D'assisi and explore the UNESCO world heritage-listed features. Next, make your way to Eremo Delle Carceri, another highlight in Santa Maria degli Angeli. When you’re done exploring the monastery, continue to Basilica Di Santa Chiara, a symbolic church.

Set your GPS to Santa Maria degli Angeli and hit the road. Expect a journey of approximately 11 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Santa Maria degli Angeli beckons with new experiences!

For a more meaningful self-guided tour of the town's best attractions, visit Basilica Of Santa Maria Degli Angeli, a captivating church that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Don’t miss out on dining at Ristorante Buca Mario, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Agricola Toscana, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

After enjoying a fulfilling meal, continue your evening at Gosh*, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Antico Caffè Del Moro - Art Bar Firenze offers a welcoming atmosphere for easing into the nightlife. Similarly, Quelo Bar provides an excellent environment for a relaxed and enjoyable evening.

Relax and recharge in preparation for another adventurous day in Italy!