14-Day Self-Drive Road Trip in Italy, France, and Switzerland With Itinerary from Rome to Siena, Milan, Basel, Mulhouse, Lugano, and Florence

On day 2, you will wake up in Rome with an entire day of wonders ahead of you! You still have 1 night left in Rome before it’s time to get back on the road and continue your European tour across Italy, France, and Switzerland.

Rome is brimming with adventures.

Awaiting your discovery is the iconic Colosseum, an UNESCO world heritage-designated archeological site in Rome. Next, go to Roman Forum.

After visiting Colosseum and Roman Forum, have a stroll along Rome's streets and take in the local charm. Continue your sightseeing by heading to Pantheon. This culturally significant monument offers a unique experience. Piazza Navona is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Castel Sant'angelo, one of the most romantic places to visit in Rome.

Bring home unique finds from Rome's bustling shopping hub, Galleria San Pietro. Enjoy a leisurely exploration of unique stores where locals shop. Don’t forget to browse souvenirs and local specialties that make perfect gifts for your loved ones. Beyond shopping, Galleria San Pietro offers plenty of options, including primary services, unique landmarks, and community events.

Get ready to savor the tastiest bites and enjoy a lively evening in Rome. From mouthwatering restaurants to happening bars, we've got the inside scoop on where to eat and drink at this stop on your multi-country road trip across Italy, France, and Switzerland.

Set out on a gastronomic journey in Rome by reserving a table at La Pergola. Renowned for its 3-star Michelin recognition, this restaurant presents an outstanding menu of mediterranean and contemporary cuisine. For a different taste, head over to Il Pagliaccio, renowned for its delectable creative and innovative dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Enoteca La Torre, a highly rated local gem known for its exquisite mediterranean and creative menu. With a 2-star Michelin acclaim, it promises a dining experience you won't want to miss.

Round off your dining experience by visiting Sant' Eustachio Caffè, a prime location for a drink. Alternatively, explore the distinctive characteristics of Yellowsquare Rome, a bar catering to every mood and preference. Caffè Portofino likewise offers a unique atmosphere, perfect for a memorable night out.

Savor the moment and raise a toast to yet another amazing day of your vacation in Italy, France, and Switzerland! Enjoy your evening in Rome to the fullest!

Embark on another extraordinary experience on day 3 of your multi-country road trip in Europe. The highlights of today include Rome in Italy. At the end of the day, you will enjoy the comforts of a top-rated hotel in Siena, your home for 1 night.

Whatever your travel style is, Trevi Fountain is an essential stop in Rome. This timeless monument provides an insightful glimpse into the city's identity. Next, discover Piazza Di Spagna, a history-steeped public square, promising a delightful encounter.

Continue your sightseeing with a visit to Spanish Steps, a widely recognized public square. When you’re done, don’t forget to make a stop at the famous Piazza Del Popolo. Round off your day at Villa Borghese, another gem in Rome with romantic features to discover.

An exhilarating day of exploring and driving will have you longing for a comfortable bed at the end of the day. Fortunately, Siena’s top hotels offer a lovely retreat at day’s end. Choose from options ranging from budget to luxury.

As the day slows down and turns into evening, indulge your taste buds at one of the top-rated restaurants in Siena. After a delicious dinner, experience the local nightlife or unwind at one of the city’s most popular bars.

Dine in style at Enoteca I Terzi, a top recommendation for dinner tonight. Or, for a change of pace, Ristorante Tar-Tufo boasts a menu that's sure to impress. Also, be sure to check out Antica Trattoria Papei. Known as a local hotspot, it’s a great choice for tonight in Siena.

Keep the evening going at Meet Life Cafè, a great choice for enjoying the after-dinner hours with a drink. You could also go to Maudit Pub, which offers a similarly pleasant setting and great drinks. Another option is Bar Impero Siena, which provides an inviting environment for unwinding after a busy day out.

Savor the moment and raise a toast to yet another amazing day of your vacation in Italy, France, and Switzerland! Enjoy your evening in Siena to the fullest!

Wake up and see what day 5 of your great European road trip in Italy, France, and Switzerland has in store for you! You will be staying in Milan for 1 night before continuing your journey to the next destination.

Check out the well-known public square, Piazza Gae Aulenti. Afterward, continue to Pinacoteca Di Brera, an art gallery every traveler should visit. As you explore Milan’s charming streets, take in the lively atmosphere and get to know the character of the city.

Next, make your way to La Scala. This locally renowned opera house is an essential stop. Following that, head to Galleria Vittorio Emanuele Ii, another must-visit site that will enhance your experience. Don’t forget to stop by Duomo Di Milano Museum, a world-famous church in the city.

As the sun sets, freshen up and head out to discover the best dining spots in Milan. Check out our recommendations on where to wine and dine while seeing this marvelous destination in Italy in a new light.

Treat yourself to a wonderful meal at Dessert Bar Milano, a top-rated dining spot in Milan. If you're in the mood for something new, try Radisson Blu Hotel Milan, another premier location with a delectable menu. You might also want to book a table at Ristorante Qui Si Mangia. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Milan.

Continue your lively evening at Kilburn Cocktail Bar Milano, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bar Frida is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, The Friends Pub Milano ensures a night out tailored to your taste.

Relax, recharge, and look forward to what tomorrow holds. The opportunities are endless with a European self-drive tour!

On day 6 of your multi-country road trip across Italy, France, and Switzerland, you'll get a true taste of the freedom a self-drive vacation entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places to see in Milan in Italy and Lucerne in Switzerland. In the evening, you’ll end up in Basel, where you will stay for 1 night.

Awaiting your discovery is the extraordinary Sforzesco Castle Art Library, a historic castle in Milan. Next, go to Parco Sempione.

After visiting Sforzesco Castle Art Library and Parco Sempione, have a stroll along Milan's streets and take in the local charm. Continue your sightseeing by heading to Arch Of Peace. This picture-perfect monument offers a unique experience.

Fasten your seatbelt and make your way to your next stop — Lucerne, home to many well-known sights in the region. Keep in mind that your travel time from Milan to Lucerne may take around 2 hours 58 min without traffic disruptions. Upon arrival in Lucerne, we highly recommend checking out some of the top attractions.

Savor the day by heading to Chapel Bridge, a captivating historical landmark that draws visitors from near and far.

Take some time off from the road, it’s time to check in at a top-rated stay in Basel. Choose a hotel where you can gently let go of the day’s excitement and enjoy some peace and relaxation.

Before this day of your vacation comes to a close, treat your palate to a taste of Switzerland's delectable cuisine at one of Basel's best restaurants. After a nice meal, enjoy the local nightlife or unwind with a drink or two in the city’s most recommended bars.

Experience a harmony of flavors at Cheval Blanc by Peter Knogl in Basel by securing a reservation in advance. Known for its 3-star Michelin status, Cheval Blanc by Peter Knogl offers a delightful variety of dishes highlighting its delicious classic french menu. If you're seeking an alternative culinary experience, be sure to explore roots, a highly recommended restaurant known for its enticing modern and seasonal cuisine. This popular 2-star Michelin-awarded venue consistently exceeds expectations, ensuring a memorable holiday experience. Ready for another culinary adventure? Indulge your senses at Stucki - Tanja Grandits, a highly acclaimed restaurant celebrated for its exceptional creative and modern menu.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Schall Und Rauch Bar, a well-loved spot among locals and tourists. Or, head to Grenzwert Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at 8 Bar, another top-rated place in the area.

Relax, recharge, and look forward to what tomorrow holds. The opportunities are endless with a European self-drive tour!

Dive into day 7 of your remarkable multi-country road trip across Italy, France, and Switzerland. Today's main destinations are Basel in Switzerland, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Mulhouse. You’ll stay here for 2 nights.

Visiting Middle Bridge is always a good idea. This worthwhile historical landmark is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the grand wonders of Basel Minster, a must-see church in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Tinguely Fountain. This often recommended art installation offers an enriching experience. For a change of pace, head to Basel Zoo, where you can take in visually striking features.

Relax your senses after a day of exhilarating activities and fun exploration. Retreat to one of the best accommodations in Mulhouse.

In the evening, prepare to be amazed by Mulhouse’s regional flavors and culminate your day with a toast. We’ve curated a guide to the city’s culinary and nightlife hotspots to enhance your experience during your multi-country vacation in Italy, France, and Switzerland.

Make sure to reserve a table at Volfoni Mulhouse, an iconic dining spot in Mulhouse. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Winstub Factory, a popular restaurant in Mulhouse. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Restaurant Aux Halles du Marché, a hidden gem nestled in Mulhouse. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to Shamrock, ideal for a leisurely evening with a drink in hand. Pub Murphy's is another bar that offers an enjoyable setting. Similarly, La Quille is also a popular place to go on a night out, perfect for relaxing and socializing.

Celebrate day 7 of your multi-country road trip in Europe with a toast, and look forward to more memorable moments to come!

Greet day 8 of your multi-country road trip across Italy, France, and Switzerland with a smile and start your day with a hearty breakfast. On today's agenda, you’ll find only the best things to see and do in Colmar in France. You will return to Mulhouse for your remaining 1 night in the city later today.

When you’re ready to jump back into the car and say goodbye to Mulhouse, you’ll hit the road in the direction of Colmar. This drive usually takes around 42 min.

Our first attraction recommendation in Colmar is Musée Bartholdi, a frequently visited museum that draws attention for its heritage-rich features. Spend some time soaking in the atmosphere before continuing to St Martin's Church, a stunning church that stands out in the town.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Petite Venise In Colmar, a well-known street that offers a unique experience. Be sure to also explore Petit Train Touristique De Colmar (vert) - Train's, a nearby tramway, highly recommended by other travelers.

When you’ve had your share of Colmar, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Munster. Your travel time is around 24 min.

Savor the day by heading to Parc Naturel Régional Des Ballons Des Vosges, a popular nature reserve that draws visitors from near and far.

In the evening, prepare to be amazed by Mulhouse’s regional flavors and culminate your day with a toast. We’ve curated a guide to the city’s culinary and nightlife hotspots to enhance your experience during your multi-country vacation in Italy, France, and Switzerland.

Treat yourself to a delicious dinner at Au Bureau Mulhouse, an excellent option for tonight's dining. Looking for something different? Les Saveurs Du Liban offers a tantalizing alternative with its diverse menu. And don’t miss L'Entrecôte de Mulhouse. Known for great service, it’s a fantastic choice for tonight in Mulhouse.

Unwind after your meal by stepping into Les 3 Singes - Mulhouse. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Le Pub Fiction offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook The Tavern Of The Teutonic Knights, another top-rated bar in the area.

Relax, recharge, and look forward to what tomorrow holds. The opportunities are endless with a European self-drive tour!

Experience an unparalleled adventure on day 9 of your multi-country journey across Italy, France, and Switzerland. This exciting part of your road trip invites you to discover the renowned landmarks in Colmar in France. After a day filled with exploration and new experiences, you will retreat to Lugano where you'll spend 1 night of well-deserved relaxation.

Embrace the thrill of the open road as you wave goodbye to Mulhouse and set your GPS to Colmar. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 38 min. Upon reaching Colmar, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

For a more meaningful self-guided tour of the town's best attractions, visit Statue De La Liberté, an often recommended monument that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Parc Du Champ De Mars and admire its awe-inspiring features.

When you’re ready, continue to Fontaine Dédiée À L'amiral Bruat, an often recommended monument beloved by locals and tourists alike. Don't miss out on Jardin Méquillet, another highlight of the area that promises a memorable visit.

After a long day of driving and exploring, you’ll check in at a top-recommended hotel in Lugano of your choice.

As the sun sets on day 9 of your multi-country road trip in Europe, prepare for a culinary journey at Lugano's top restaurants and eateries. After a fulfilling dinner, dive into the town’s local nightlife.

Set out on a gastronomic journey in Lugano by reserving a table at Flamel. Renowned for its Bib Gourmand award, this restaurant presents an outstanding menu of contemporary and seasonal cuisine. Looking for something different? Lanchetta Lounge Bar & Pinsa. Offers a tantalizing alternative with its diverse menu.

Continue your evening by exploring the vibrant nightlife scene at Il Fermento, a prime destination for a thrilling night out. Also, don’t forget to check out Bar Oops, a bar that offers unique local touches.

As the night falls in Lugano, take a moment to savor the experiences of the day. Wash away your fatigue with a drink, or lie back and relax at your hotel, and look forward to another thrilling day of your multi-country journey across Europe.

Day 11 of your multi-country road trip promises a full day of discoveries in beautiful Florence. Enjoy time off the road as you have 2 nights left in the city.

Whether you decide to explore Florence on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Look forward to a unique sightseeing adventure at the notable Basilica Of Santa Croce In Florence and allow yourself time to explore. Just a short distance away you'll find your next stop, Piazza Della Signoria, a grand public square that draws visitors from far and near.

Continue your journey to Uffizi Gallery, one of the city’s most spectacular spots that you shouldn’t miss. Another great site to visit is the timeless Ponte Vecchio. When you're finished at the historical landmark, Piazzale Michelangelo awaits your visit. This observation deck is a grand highlight on today's itinerary.

As the day unfolds, you’ll be delighted to find that Florence boasts an array of restaurants and bars catering to every budget. Take this opportunity to sample the distinctive flavors of the region.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After savoring a delicious meal, step into the vibrant nightlife at Bar 50 Rosso, where the evening is just getting started. In the same way, Bitter Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Archea Brewery is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Take in the ambiance of Florence as this day slowly comes to an end. Whether you’re going bar hopping or you decide on a quiet night at your hotel, you have another exciting day of your multi-country road trip to look forward to!

On day 12, you will wake up in Florence with an entire day of wonders ahead of you! You still have 1 night left in Florence before it’s time to get back on the road and continue your European tour across Italy, France, and Switzerland.

The Boboli Gardens is must-visit botanical garden and a great option for a daytime tour of the area. Continue your journey to Cathedral Of Santa Maria Del Fiore, an extraordinary church, located just a leisurely stroll away. Next, head to Central Market, a picture-perfect food market, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Florence. When you're ready, let your sightseeing route take you to the locally renowned Galleria Dell'accademia. If you’re looking for more, David is also a well-known attraction that is worthwhile a visit.

As the day slows down and turns into evening, indulge your taste buds at one of the top-rated restaurants in Florence. After a delicious dinner, experience the local nightlife or unwind at one of the city’s most popular bars.

Enjoy a lovely meal at Ristorante Buca Mario, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Agricola Toscana is another top choice with a popular menu. You could also check for a table at Eataly Firenze. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

Explore the vibrant nightlife at Gosh* after your meal, a hub for lively evenings and memorable moments. Or, head to Antico Caffè Del Moro - Art Bar Firenze for a great selection of flavorful drinks and a charming setting. Furthermore, Quelo Bar is perfect for those looking to extend their night with a touch of local flavor.

Celebrate day 12 of your multi-country road trip in Europe with a toast, and look forward to more memorable moments to come!

When you’re not exploring the city and its surrounding areas, take time to relax at your selected hotel in Rome, where you’ll be staying for 1 night.

Set your GPS to Vatican City, Vatican City and hit the road. Expect a journey of approximately 3 hours 11 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Vatican City beckons with new experiences!

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Saint Peter's Square, a notable square that offers a unique experience. Be sure to also explore St. Peter's Basilica, a nearby major basilica, highly recommended by other travelers.

An exhilarating day of exploring and driving will have you longing for a comfortable bed at the end of the day. Fortunately, Rome’s top hotels offer a lovely retreat at day’s end. Choose from options ranging from budget to luxury.

As the sun sets, freshen up and head out to discover the best dining spots in Rome. Check out our recommendations on where to wine and dine while seeing this marvelous destination in Italy in a new light.

Enjoy a lovely dining experience at Hotel de Russie, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at La Taverna Italiana, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated The Parrot Bar. It’s yet another ideal choice to enhance your time in Rome tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, The Apartment Bar Roma stands out as an excellent choice for a post-dinner cocktail. Alternatively, Hotel Hassler Roma offers an ideal atmosphere to enjoy the pleasures of the night.

Spend the evening looking over your itinerary for tomorrow and reminisce about what you’ve seen and done so far on your European road trip adventure. New experiences await!