13-Day Italy Self-Drive Road Trip With Itinerary from Rome to Florence, Siena, La Spezia, Venice, and Bologna

Day 2 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 2 nights left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Colosseum leaves a lasting impression. This archeological site is one of the most wondrous places to visit in Rome. Next, head to Roman Forum, an iconic archeological site, known for its UNESCO world heritage-listed features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Trevi Fountain. This visually striking monument is a highly recommended experience. Nearby, you'll also find Pantheon and Piazza Navona Visit these for an interesting touch to your journey. Finish the day with a visit to Castel Sant'angelo, a romantic castle in Rome.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

After savoring a delicious meal, step into the vibrant nightlife at Sant' Eustachio Caffè, where the evening is just getting started. In the same way, Yellowsquare Rome offers a unique charm perfect for experiencing the local bar scene in Rome. Caffè Portofino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 3 of your road trip, you'll get the chance to experience Vatican City and Rome. At the end of the day, you'll drive back to Rome, where you still have 1 night left to stay.

Set aside time today to explore Trastevere, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Whatever your travel style is, Piazza Di Spagna is an essential stop in Rome. This timeless public square provides an insightful glimpse into the city's identity. Next, discover Spanish Steps, a symbolic public square, promising a delightful encounter.

It’s time to gear up for the next part of your road trip adventure. Upon your arrival in Vatican City, you’ll be greeted with the opportunity to do some sightseeing and exploring.

One of our top recommendations for your sightseeing is Vatican Museums. Then, head to Sistine Chapel. This spectacular chapel is a traveler-favorite in the city.

If you're keen to see more, continue to St. Peter's Basilica. Feed your curiosity by learning something new about the major basilica.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Keep the evening going at The Apartment Bar Roma, a great choice for enjoying the after-dinner hours with a drink. You could also go to Hotel Hassler Roma, which offers a similarly pleasant setting and great drinks.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 2 nights.

Embrace the thrill of the open road as you wave goodbye to Rome and set your GPS to Florence. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 3 hours 6 min. Upon reaching Florence, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Set out on a self-guided sightseeing tour at Piazzale Michelangelo and explore the symbolic features. Next, make your way to Basilica Of Santa Croce In Florence, another highlight in Florence. When you’re done exploring the church, continue to Uffizi Gallery, an eye-catching art gallery.

Nearby, you will also find Ponte Vecchio. This world-famous historical landmark is a top place to see in the area. Lastly, head to Piazza Della Signoria, an enchanting public square that is perfect for some final exploring in the city.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Ristorante Oliviero 1962, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Di Poneta Novoli, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Caffe San Firenze. It’s yet another ideal choice to enhance your time in Florence tonight.

Round off your dining experience by visiting Manifattura, a prime location for a drink. Alternatively, explore the distinctive characteristics of Se·sto On Arno Rooftop Bar, a bar catering to every mood and preference. Il Vinile likewise offers a unique atmosphere, perfect for a memorable night out.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Florence, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Florence and Pisa.

Awaiting your discovery is the top-rated Cathedral Of Santa Maria Del Fiore, an UNESCO world heritage-designated church in Florence. Next, go to Galleria Dell'accademia.

Embrace the thrill of the open road as you wave goodbye to Florence and set your GPS to Pisa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 23 min. Upon reaching Pisa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Leaning Tower Of Pisa. Spend some time admiring the breathtaking features of the monument before you continue to your next stop. Then, head to Pisa Cathedral. This locally appreciated church is a traveler-favorite in the city.

If you're keen to see more, continue to Piazza Del Duomo, Pisa. Feed your curiosity by learning something new about the public square.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Enjoy a lovely dining experience at Ditta Artigianale, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Trattoria Da Burde, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Casa Toscana. It’s yet another ideal choice to enhance your time in Florence tonight.

To truly maximize your evening out, consider visiting Bar 50 Rosso after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bitter Bar, another bar with an inviting ambiance. Similarly, Archea Brewery also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Your itinerary for day 6 of your road trip in Italy includes 2 stops and features some of the highlights of Siena and San Gimignano. At the end of the day, enjoy the comforts of a top-rated hotel in Siena, where you'll spend 1 night.

Siena’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Florence behind. This drive usually takes around 1 hour 12 min. Siena welcomes you with a multitude of unique vacation experiences.

One of our top recommendations for your sightseeing is Siena Cathedral. Spend some time admiring the majestic features of the church before you continue to your next stop. Then, head to Piazza Del Campo. This extraordinary public square is a traveler-favorite in the city.

If you're keen to see more, continue to Porta Camollia, Siena. Feed your curiosity by learning something new about the monument.

Admire the views and listen to some good music as you drive in the direction of San Gimignano.

Savor the day by heading to Parco Della Rocca, an up-and-coming park that draws visitors from near and far. When you're done, continue to Sangimignano1300, where you can soak in the photogenic surroundings.

Next, explore Piazza Del Duomo, yet another beloved place to see in the area.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a wonderful meal at Enoteca I Terzi, a top-rated dining spot in Siena. If you're in the mood for something new, try Ristorante Tar-Tufo, another premier location with a delectable menu. You might also want to book a table at Antica Trattoria Papei. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Siena.

After enjoying a fulfilling meal, continue your evening at Meet Life Cafè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Maudit Pub offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Impero Siena provides an excellent environment for a relaxed and enjoyable evening.

Celebrate another amazing day of your road trip adventure in Italy!

On day 7 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Riomaggiore are on today's agenda. In the evening, you’ll end up in La Spezia, where you will stay for 2 nights.

After soaking in Siena’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Riomaggiore. Expect your car journey to take a minimum of 2 hours 50 min. When you arrive in Riomaggiore, it's time to take a break from the road.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Church Of San Giovanni Battista Of Riomaggiore, a worthwhile church that everyone visiting Riomaggiore should see. Next, head to Riomaggiore.

If you're keen to see more, don’t miss out on Castle Of Riomaggiore, a history-steeped castle popular among locals as well as travelers.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in La Spezia. La Spezia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

La Spezia is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in La Spezia.

Enjoy a lovely meal at The Colombaio Park, a top-rated place to have dinner tonight.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 8 of your road trip, you’ll start and end your day in La Spezia, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Manarola.

Whether you decide to explore Manarola on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

After soaking in La Spezia’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Manarola. Expect your car journey to take a minimum of 28 min. When you arrive in Manarola, it's time to take a break from the road.

Savor the day by heading to Chiesa Di San Lorenzo, an increasingly popular church that draws visitors from near and far. When you're done, continue to Presepe Di Manarola, where you can soak in the enchanting surroundings.

Next, explore Manarola Overlook Viewpoint, yet another worthwhile place to see in the area.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in La Spezia.

After a day of adventure, treat yourself to an exquisite dinner at one of La Spezia's best restaurants.

Get a good night's sleep and look forward to another great day on the road in Italy!

Dive into day 9 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Venice. At the end of the day, you’ll unwind at one of the finest accommodations in Venice, where you'll spend 2 nights.

Continue your road trip and head to your next destination, Venice. This car ride takes around 4 hours 12 min.

Spend your afternoon discovering Bridge Of Sighs, an interesting monument known for its UNESCO world heritage-listed features. Next, continue your sightseeing at Doge's Palace, a captivating palace.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by St Mark's Basilica and uncover the details of this romantic church. Make sure to also explore St Mark's Campanile, an intriguing monument. For your last stop, consider Piazza San Marco, a visually striking public square that many travelers find worth the detour.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Bauer Hotel, an excellent option for tonight's dining. Looking for something different? L'Osteria Le Guglie offers a tantalizing alternative with its diverse menu. And don’t miss Corner Pub. Known for great service, it’s a fantastic choice for tonight in Venice.

If you’re not ready to end the night just yet, Al Parlamento offers a perfect venue to relax and savor a drink. Similarly, The Caffe Rosso is well-suited for those looking to unwind in a social setting. Adagio is another excellent spot to enjoy a nightcap after a delightful meal.

Relax and recharge in preparation for another adventurous day in Italy!

Day 10 offers an itinerary packed with the best things to see in Rome. You’ll stay in Venice for 1 night more, offering you enough time to explore at a relaxed pace.

Make a stop at Palazzo Contarini Del Bovolo. This captivating palace is a must-visit for travelers looking for a unique holiday experience. Make your way to Rialto Bridge located in Venice for another exciting encounter.

Next, immerse yourself in the setting of Grand Canal. Its UNESCO world heritage-listed features will captivate you.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at Generator Venice, a top pick for dinner tonight. Alternatively, Nevodi beckons with its unique menu offerings. Also, consider Ristorante La Piazza. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

Unwind after your meal by stepping into Il Mercante. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, The Irish Pub Venezia offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Ai Stagneri, another top-rated bar in the area.

Relax and look forward to more memorable moments to come!

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Bologna. When you’re not sightseeing, take time to relax at your chosen hotel in Bologna, where you’ll be staying for 1 night.

Set your GPS to Bologna and hit the road. Expect a journey of approximately 1 hour 46 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Bologna beckons with new experiences!

Our first attraction recommendation in Bologna is Piazza Santo Stefano, an intriguing public square that draws attention for its inviting features. Spend some time soaking in the atmosphere before continuing to Two Towers, a picture-perfect monument that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Palazzo Grassi, Bologna, an underrated palace that offers a unique experience. Be sure to also explore Fountain Of Neptune, Bologna, a nearby monument, highly recommended by other travelers. End your self-guided tour at Piazza Maggiore, a visually striking public square and the perfect final attraction in Bologna.

When you’re done exploring for the day, you’ll drive to your hotel in Bologna. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Bologna. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Ristorante Ciacco, a highly-rated dining destination in Bologna. If you're eager to try something different, consider Ristorante Ballarini, another top spot with a tantalizing menu. You might also want to secure a reservation at Sfoglia Rina. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Bologna this evening.

Extend your evening after a delightful meal by visiting Bar Al Bricco D'oro, which offers the perfect atmosphere for a night out. Moreover, Bar Freud E Squisito is another popular option for a drink or two. Likewise, Osteria Del Sole also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Savor another day of unforgettable experiences in Italy!

Experience an unparalleled adventure on day 12 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Modena. At the end of the day, you will retreat to the hotel of your choice in Rome, where will spend 1 night.

When you’ve had your share of Bologna, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Modena. Your travel time is around 52 min.

For a more meaningful self-guided tour of the city's best attractions, visit Enzo Ferrari Museum, a popular museum that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Torre Civica - Ghirlandina and admire its UNESCO world heritage-listed features.

When you’re ready, continue to Duomo Di Modena, a notable church beloved by locals and tourists alike.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Have a fantastic dining experience at Sofitel Roma Villa Borghese, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Centro offers an enticing alternative with its varied menu. Additionally, Ristorante Tema is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

Head back to your accommodation in Rome and get some rest to prepare for another magical day of your road trip in Italy.