13-Day Italy Self-Drive Road Trip With Itinerary from Florence traveling south to Siena, Perugia, Rome, Naples, and Amalfi

Day 2 of your road trip will take you to the best attractions Florence has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Florence.

Whether you decide to explore Florence on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Your adventure in Florence is only getting started when you visit Galleria Dell'accademia, a notable local hot spot. Another notable attraction to explore is Piazza Della Signoria. This widely recognized public square is known for its history-steeped appeal.

After soaking in the highlights of these sights, take some time to wander Florence's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Ponte Vecchio. This romantic historical landmark offers a fascinating experience that many visitors find memorable. Uffizi Gallery is also worth visiting, along with Basilica Of Santa Croce In Florence. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Piazzale Michelangelo. This impressive observation deck provides a fitting finale to your sightseeing.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor the flavors at Ditta Artigianale, a top pick for dinner tonight. Alternatively, Trattoria Da Burde beckons with its unique menu offerings. Also, consider Casa Toscana. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

To truly maximize your evening out, consider visiting Bar 50 Rosso after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bitter Bar, another bar with an inviting ambiance. Similarly, Archea Brewery also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

On day 3 of your road trip, you’ll start and end your day in Florence, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Pisa and Lucca.

Embrace the thrill of the open road as you wave goodbye to Florence and set your GPS to Pisa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 16 min. Upon reaching Pisa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Our first attraction recommendation in Pisa is Piazza Del Duomo, Pisa, a world-famous public square that draws attention for its breathtaking features. Spend some time soaking in the atmosphere before continuing to Leaning Tower Of Pisa, a culturally significant monument that stands out in the city.

Lucca’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Pisa behind. This drive usually takes around 32 min. Lucca welcomes you with a multitude of unique vacation experiences.

Our first attraction recommendation in Lucca is Piazza Dell'anfiteatro, a well-known public square that draws attention for its romantic features. Spend some time soaking in the atmosphere before continuing to Guinigi Tower, an enchanting monument that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Mura Di Lucca, an underrated historical landmark that offers a unique experience.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a delicious meal at Ristorante Buca Mario, a highly-rated dining destination in Florence. If you're eager to try something different, consider Agricola Toscana, another top spot with a tantalizing menu. You might also want to secure a reservation at Eataly Firenze. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Gosh*, a well-loved spot among locals and tourists. Or, head to Antico Caffè Del Moro - Art Bar Firenze. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Quelo Bar, another top-rated place in the area.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Siena and San Gimignano. At the end of the day, you’ll unwind at one of the finest accommodations in Siena, where you'll spend 2 nights.

When you’re ready to jump back into the car and say goodbye to Florence, you’ll hit the road in the direction of Siena. This drive usually takes around 1 hour 12 min.

One of our top recommendations for your sightseeing is Siena Cathedral. Spend some time admiring the inviting features of the church before you continue to your next stop. Then, head to Piazza Del Campo. This famous public square is a traveler-favorite in the city.

If you're keen to see more, continue to Tower Of Mangia. Feed your curiosity by learning something new about the monument.

Fasten your seatbelt and make your way to your next stop — San Gimignano, home to many well-known sights in the region. Upon arrival in San Gimignano, we highly recommend checking out some of the top attractions.

When you're ready for some sights, head to Chiesa Di Sant'agostino, a worthwhile church in San Gimignano. Explore its inviting features at your own pace before you continue your journey to your next attraction, Palazzo Comunale, Pinacoteca, Torre Grossa. This often recommended museum is a top recommendation in the area.

When you’re ready to explore more, Piazza Del Duomo is an excellent choice. Spend some time discovering what some claim to be the most visually striking public square in the region.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Siena's best restaurants.

Enjoy a delicious meal at Enoteca I Terzi, a highly-rated dining destination in Siena. If you're eager to try something different, consider Ristorante Tar-Tufo, another top spot with a tantalizing menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Siena this evening.

After your meal, keep the night alive at a bar like Meet Life Cafè, known for its lively atmosphere. Maudit Pub is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Impero Siena offers an excellent atmosphere for those looking to amp up the evening.

Celebrate another amazing day of your road trip adventure in Italy!

Wake up to day 5 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Pievasciata, San Regolo, Castellina in Chianti, and San Donato in Poggio. With 1 night to stay in Siena, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

When you’ve had your share of Siena, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Pievasciata. Your travel time is around 26 min.

Parco Sculture Del Chianti is an intriguing sculpture garden we recommend visiting today. Discover its noteworthy features before continuing your self-guided tour.

After soaking in Pievasciata’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: San Regolo. Expect your car journey to take a minimum of 21 min. When you arrive in San Regolo, it's time to take a break from the road.

Savor the day by heading to Castello Di Brolio, an up-and-coming castle that draws visitors from near and far.

When you’re ready to jump back into the car and say goodbye to San Regolo, you’ll hit the road in the direction of Castellina in Chianti. This drive usually takes around 43 min.

Spend your afternoon discovering Rocca Di Castellina In Chianti, a curiosity-inducing castle known for its history-steeped features.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Osteria Quattro Venti, a top-rated dining spot in Siena. If you're in the mood for something new, try Fischi per Fiaschi, another premier location with a delectable menu. You might also want to book a table at Osteria da Divo. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Siena.

After your meal, keep the night alive at a bar like Charlie Mixology Bar Di Aldinucci Riccardo, known for its lively atmosphere. Bar Pinacoteca is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, San Paolo Pub offers an excellent atmosphere for those looking to amp up the evening.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 6 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Santa Maria degli Angeli and Perugia are on today's agenda. In the evening, you’ll end up in Perugia, where you will stay for 1 night.

Set your GPS to Santa Maria degli Angeli and hit the road. Expect a journey of approximately 1 hour 39 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Santa Maria degli Angeli beckons with new experiences!

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Chiesa Nuova Di San Francesco Convertito, a beloved church that everyone visiting Santa Maria degli Angeli should see. Next, head to Rocca Maggiore. This visually striking castle is one of the most often recommended attractions in the region.

If you're keen to see more, don’t miss out on Basilica Of San Francesco D'assisi, a stunning church popular among locals as well as travelers.

Continue your road trip and head to your next destination, Perugia. This car ride takes around 27 min.

Set out on a self-guided sightseeing tour at Rocca Paolina and explore the history-steeped features. Next, make your way to Perugia Sotterranea Accesso, another highlight in Perugia. When you’re done exploring the cave system, continue to Piazza Iv Novembre, a romantic public square.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Perugia. Perugia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Perugia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Ristorante Settimo Sigillo, a top-rated dining destination in Perugia. If you're in the mood to try something new, consider Caffè Baglioni, another top spot with a mouthwatering menu. You might also want to secure a reservation at Bar Pellas. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Perugia this evening.

Unwind after your meal by stepping into Tommi Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Valentina offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Caffe Dal Perugino, another top-rated bar in the area.

Raise your glass to another unforgettable day in Italy!

Your itinerary for day 7 of your road trip in Italy includes 1 stop and features some of the highlights of Orvieto. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 3 nights.

Continue your road trip and head to your next destination, Orvieto. This car ride takes around 1 hour 19 min.

When you're ready for some sights, head to Orvieto Cathedral, an interesting church in Orvieto. Explore its majestic features at your own pace before you continue your journey to your next attraction, Museo Dell'opera Del Duomo. This curiosity-inducing museum is a top recommendation in the area.

When you’re ready to explore more, Orvieto Underground is an excellent choice. Spend some time discovering what some claim to be the most history-steeped cave system in the region.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Let the evening flow smoothly from dinner to drinks at La Botticella Of Poggi Giovanni, a top-rated bar in the area. For other recommendations, Almalu Trastevere provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Viminale Di Pepi Maurilio offers a memorable night with diverse drink options and excellent service.

Savor another day of unforgettable experiences in Italy!

Greet day 8 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 2 nights to stay in Rome, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Rome and Vatican City.

No visit to Rome is complete without Colosseum. This world-famous archeological site is one of the top attractions in the city. Proceed to Roman Forum, another must-visit attraction.

As you wander through the inviting streets of Rome, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Trevi Fountain. This wondrous monument is a traveler-favorite. Not far away, you’ll find Pantheon, another key site on your sightseeing itinerary. Piazza Navona is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Don’t miss out on dining at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After savoring a delicious meal, step into the vibrant nightlife at Sant' Eustachio Caffè, where the evening is just getting started. In the same way, Yellowsquare Rome offers a unique charm perfect for experiencing the local bar scene in Rome. Caffè Portofino is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Celebrate another amazing day of your road trip adventure in Italy!

On day 9 of your road trip in Italy, you’ll start and end your day in Rome, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Rome, there’s no need to rush. Experience Tivoli to the fullest today with this curated day itinerary.

Tivoli is brimming with adventures.

After soaking in Rome’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Tivoli. Expect your car journey to take a minimum of 38 min. When you arrive in Tivoli, it's time to take a break from the road.

For a more meaningful self-guided tour of the town's best attractions, visit Hadrian's Villa, a beloved archeological site that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Villa D'este and admire its romantic features.

When you’re ready, continue to Fontana Dell'organo, an intriguing monument beloved by locals and tourists alike. Don't miss out on Gregorian Bridge, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Villa Gregoriana, an eye-catching place to see that you won’t regret spending some extra time discovering.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Hotel de Russie, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Let the evening flow smoothly from dinner to drinks at The Apartment Bar Roma, a top-rated bar in the area. For other recommendations, Hotel Hassler Roma provides a perfect setting for rounding out your night with style and great drinks.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 10 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Naples. At the end of the day, you will retreat to the hotel of your choice in Naples, where will spend 1 night.

Embrace the thrill of the open road as you wave goodbye to Rome and set your GPS to Naples. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 32 min. Upon reaching Naples, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Savor the day by heading to Castel Sant'elmo, a well-known castle that draws visitors from near and far. When you're done, continue to Naples National Archaeological Museum, where you can soak in the photogenic surroundings.

Next, explore Cappella Sansevero, yet another well-known place to see in the area. After the museum, make time to go to Spaccanapoli. This visually striking street is well worth the visit.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a wonderful meal at L'Oca Nera Irish Pub, a top-rated dining spot in Naples. If you're in the mood for something new, try Mimì alla Ferrovia, another premier location with a delectable menu. You might also want to book a table at Spuzzulè Winebar. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Naples.

After enjoying a fulfilling meal, continue your evening at Happening Cocktail Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Shanti Art Musik Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Gran Caffè Gambrinus provides an excellent environment for a relaxed and enjoyable evening.

Relax and look forward to more memorable moments to come!

On day 11 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 4 destinations, including Ottaviano, Pompei, Ravello, and Amalfi. When you’re not sightseeing, take time to relax at your chosen hotel in Amalfi, where you’ll be staying for 1 night.

After soaking in Naples’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Ottaviano. Expect your car journey to take a minimum of 43 min. When you arrive in Ottaviano, it's time to take a break from the road.

Our first attraction recommendation in Ottaviano is Mount Vesuvius, an intriguing volcano that draws attention for its majestic features.

When you’re ready to jump back into the car and say goodbye to Ottaviano, you’ll hit the road in the direction of Pompei. This drive usually takes around 33 min.

Our first attraction recommendation in Pompei is Archaeological Park Of Pompeii, an interesting archeological site that draws attention for its respected features. Spend some time soaking in the atmosphere before continuing to Lupanare Di Pompei, an UNESCO world heritage-listed archeological site that stands out in the city.

Embrace the thrill of the open road as you wave goodbye to Pompei and set your GPS to Ravello. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 51 min. Upon reaching Ravello, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

When you're ready for some sights, head to Villa Rufolo, a well-known historical landmark in Ravello. Explore its romantic features at your own pace before you continue your journey.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Amalfi. Amalfi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Amalfi. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at Pasticceria Pansa Amalfi, an iconic dining spot in Amalfi. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Grand Hotel Excelsior Amalfi, a popular restaurant in Amalfi. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Lido Azzurro, a hidden gem nestled in Amalfi. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Explore the vibrant nightlife at Bar Della Valle after your meal, a hub for lively evenings and memorable moments.

Say good night to Amalfi and look forward to another great day of your road trip in Italy!

Dive into day 12 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Orvieto. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 1 night.

Orvieto’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Amalfi behind. This drive usually takes around 4 hours 11 min. Orvieto welcomes you with a multitude of unique vacation experiences.

Well Of St. Patrick is a well-known monument we recommend visiting today. Discover its breathtaking features before continuing your self-guided tour.

Orvieto’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Amalfi behind. This drive usually takes around 4 hours 11 min. Orvieto welcomes you with a multitude of unique vacation experiences.

Torre Del Moro Orvieto is a frequently visited monument we recommend visiting today. Discover its picture-perfect features before continuing your self-guided tour to Pozzo Della Cava, a heritage-rich cave that’s well-regarded in the area.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Savor the flavors at Tijuana, a top pick for dinner tonight. Alternatively, Djària - American Bar beckons with its unique menu offerings. Also, consider The Florence Irish Pub. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Get a good night's sleep and look forward to another great day on the road in Italy!