11-Day Italy Self-Drive Road Trip With Itinerary from Rome to Naples, Perugia, and Florence and surrounding area

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Colosseum, Rome, Italy.
Photo of piazza de spagna in Rome, Italy.
11-Day Italy Self-Drive Road Trip With Itinerary from Rome to Naples, Perugia, and Florence and surrounding area
11-Day Italy Self-Drive Road Trip With Itinerary from Rome to Naples, Perugia, and Florence and surrounding area
11-Day Italy Self-Drive Road Trip With Itinerary from Rome to Naples, Perugia, and Florence and surrounding area
11-Day Italy Self-Drive Road Trip With Itinerary from Rome to Naples, Perugia, and Florence and surrounding area
11-Day Italy Self-Drive Road Trip With Itinerary from Rome to Naples, Perugia, and Florence and surrounding area
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Experience the freedom of the open road on an unforgettable 11-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Rome, Amalfi, Pompei, Naples, Caserta, Perugia, Pisa, and Florence.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 5 nights in Rome, 2 nights in Naples, 1 night in Perugia, and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Amalfi, Pompei, Naples, Caserta, Perugia, Pisa, and Florence, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Rome - Arrival day
  • More
  • largo di Torre Argentina
  • More

Your road trip adventure in Italy begins as soon as you reach Rome and pick up your car. You’ll stay here for 4 nights and explore what to see in Rome, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Largo Di Torre Argentina. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Rome. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at La Bottega Roma, an excellent option for tonight's dining. Looking for something different? Pasta In Corso offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria Vecchia Roma. Known for great service, it’s a fantastic choice for tonight in Rome.

After savoring a delicious meal, step into the vibrant nightlife at La Botticella Of Poggi Giovanni, where the evening is just getting started. In the same way, Almalu Trastevere offers a unique charm perfect for experiencing the local bar scene in Rome. Bar Viminale Di Pepi Maurilio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 11-day road trip in Italy!

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Day2

Day 2

  • Rome
  • More

Drive 4 km, 54 min

  • Altare della Patria
  • Capitoline Hill
  • Roman Forum
  • Colosseum
  • Circus Maximus
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Rome. You’ll stay in Rome for 3 nights.

Altare Della Patria is must-visit monument and a great option for a daytime tour of the area. Continue your journey to Capitoline Hill, a locally renowned public square, located just a leisurely stroll away. Next, head to Roman Forum, a culturally significant archeological site, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Rome. When you're ready, let your sightseeing route take you to the globally renowned Colosseum. If you’re looking for more, Circus Maximus is also a captivating attraction that is worthwhile a visit.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Set out on a gastronomic journey in Rome by reserving a table at La Pergola. Renowned for its 3-star Michelin recognition, this restaurant presents an outstanding menu of mediterranean and contemporary cuisine. For a different taste, head over to Il Pagliaccio, renowned for its delectable creative and innovative dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore Enoteca La Torre, a highly rated local gem known for its exquisite mediterranean and creative menu. With a 2-star Michelin acclaim, it promises a dining experience you won't want to miss.

Let the evening flow smoothly from dinner to drinks at Sant' Eustachio Caffè, a top-rated bar in the area. For other recommendations, Yellowsquare Rome provides a perfect setting for rounding out your night with style and great drinks. Likewise, Caffè Portofino offers a memorable night with diverse drink options and excellent service.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day3

Day 3

  • Rome
  • More

Drive 9 km, 1 hour 8 min

  • Villa Borghese
  • piazza del Popolo
  • Spanish Steps
  • Piazza di Spagna
  • Basilica di Santa Maria Maggiore
  • More

Day 3 offers an itinerary packed with the best things to see in Rome. You’ll stay in Rome for 2 nights more, offering you enough time to explore at a relaxed pace.

Catch Villa Borghese before the crowds roll in. This standout park is sure to ignite your curiosity. Next, dive into the history-steeped features of Piazza Del Popolo, a must-visit public square in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Spanish Steps, a widely recognized public square. For a change of scene, check out Piazza Di Spagna, known for its enchanting features. We also recommend visiting Basilica Di Santa Maria Maggiore. This church is a must for anyone looking to experience the city to the fullest.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Hotel de Russie, a highly-rated dining destination in Rome. If you're eager to try something different, consider La Taverna Italiana, another top spot with a tantalizing menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Rome this evening.

Explore the vibrant nightlife at The Apartment Bar Roma after your meal, a hub for lively evenings and memorable moments. Or, head to Hotel Hassler Roma for a great selection of flavorful drinks and a charming setting.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day4

Day 4

  • Rome
  • More

Drive 8 km, 1 hour 2 min

  • Trevi Fountain
  • Pantheon
  • Piazza Navona
  • Campo de' Fiori
  • Castel Sant'Angelo
  • More

Day 4 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Rome.

Trevi Fountain brings Rome's character to life. This detailed monument is a highlight of any visit in the city. Then, enjoy Pantheon, another respected attraction that never fails to captivate visitors. Next, head over to Piazza Navona, one of the city’s most world-famous attractions, known for its romantic features.

If you’re looking for more, spend time soaking in the atmosphere of Campo De' Fiori. This romantic public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Castel Sant'angelo, a spectacular castle, and take a stroll around the area.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Experience shopping bliss at Rome as you explore Trastevere. Take a leisurely stroll through unique boutique shops and stores, where local treasures are waiting to be found. Don't miss the chance to discover artisan crafts that reflect the fascinating culture of Italy. Beyond shopping, Trastevere offers more options, including unique attractions, key services, and vibrant events.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Sofitel Roma Villa Borghese, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Centro offers an enticing alternative with its varied menu. Additionally, Ristorante Tema is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Rome.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day5

Day 5

  • Rome
  • Amalfi
  • Pompei
  • Naples
  • More

Drive 342 km, 5 hours 30 min

  • Amalfi Coast
  • Archaeological Park of Pompeii
  • Amphitheatre of Pompeii
  • More

On day 5 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Amalfi and Pompei are on today's agenda. In the evening, you’ll end up in Naples, where you will stay for 2 nights.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Pompei may take around 1 hour 3 min. Upon your arrival in Pompei, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Set out on a self-guided sightseeing tour at Archaeological Park Of Pompeii and explore the instagrammable features. Next, make your way to Amphitheatre Of Pompeii, another highlight in Pompei.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Naples is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Naples.

Begin your culinary exploration in Naples by securing a reservation at Veritas. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of campanian and contemporary cuisine. For another dining delight, visit Il Comandante, celebrated for its delectable creative and mediterranean menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover ARIA, a top local spot known for its tantalizing contemporary and modern menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Happening Cocktail Bar, a well-loved spot among locals and tourists. Or, head to Shanti Art Musik Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Gran Caffè Gambrinus, another top-rated place in the area.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day6

Day 6

  • Naples
  • More

Drive 6 km, 54 min

  • Chiesa del Gesù Nuovo
  • Cappella Sansevero
  • Napoli Sotterranea Percorso Ufficiale
  • Naples National Archaeological Museum
  • More

Day 6 of your road trip across Italy promises a magnificent time exploring what to see in Naples. You have 1 night left in Naples. Take the opportunity to experience more of the best attractions and activities in the city.

Enjoy all that Chiesa Del Gesù Nuovo has to offer. This is a popular church you should not miss. Another must-see is Cappella Sansevero, an interesting museum in Naples.

When you’re ready for the next sight, head to Napoli Sotterranea Percorso Ufficiale. From there, take a leisurely stroll to Naples National Archaeological Museum, another of the city’s locally renowned attractions.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Antica Pizzeria Di Matteo, a popular restaurant in Naples. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Naples at Mercure Napoli Centro Angioino, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated La Lazzara Trattoria e Pizzeria. It’s yet another ideal choice to enhance your time in Naples tonight.

Following your dinner, dive into the local bar culture at Archivio Storico - Cocktail Bar & Wonderfood. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Archeobar, the perfect place for those looking to experience the best of the nightlife. Similarly, Babette Pub provides excellent drinks and a great atmosphere, ensuring a memorable night out.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day7

Day 7

  • Naples
  • Caserta
  • Perugia
  • More

Drive 382 km, 4 hours 39 min

  • piazza del Plebiscito
  • Ovo Castle
  • Palace of Caserta
  • More

Your itinerary for day 7 of your road trip in Italy includes 2 stops and features some of the highlights of Naples and Caserta. At the end of the day, enjoy the comforts of a top-rated hotel in Perugia, where you'll spend 1 night.

Enjoy all that Piazza Del Plebiscito has to offer. This is an astonishing public square you should not miss. Another must-see is Ovo Castle, a locally renowned castle in Naples.

Continue your road trip and head to your next destination, Caserta. This car ride takes around 44 min.

Palace Of Caserta is a captivating palace we recommend visiting today. Discover its culturally significant features before continuing your self-guided tour.

When you’re done exploring for the day, you’ll drive to your hotel in Perugia. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Perugia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Ristorante Settimo Sigillo, a top-rated dining destination in Perugia. If you're in the mood to try something new, consider Caffè Baglioni, another top spot with a mouthwatering menu. You might also want to secure a reservation at Bar Pellas. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Perugia this evening.

Round off your dining experience by visiting Tommi Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Valentina, a bar catering to every mood and preference. Caffe Dal Perugino likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day8

Day 8

  • Perugia
  • Pisa
  • Florence
  • More

Drive 353 km, 4 hours 29 min

  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Parco Regionale Migliarino, San Rossore, Massaciuccoli
  • More

Dive into day 8 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pisa and Cascine Vecchie. At the end of the day, you’ll unwind at one of the finest accommodations in Florence, where you'll spend 2 nights.

Embrace the thrill of the open road as you wave goodbye to Perugia and set your GPS to Pisa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 46 min. Upon reaching Pisa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Leaning Tower Of Pisa, an iconic monument that everyone visiting Pisa should see. Next, head to Piazza Del Duomo, Pisa. This picture-perfect public square is one of the most globally renowned attractions in the region.

If you're keen to see more, don’t miss out on Pisa Cathedral, a majestic church popular among locals as well as travelers.

Fasten your seatbelt and make your way to your next stop — Cascine Vecchie, home to many well-known sights in the region. Keep in mind that your travel time from Pisa to Cascine Vecchie may take around 9 min without traffic disruptions. Upon arrival in Cascine Vecchie, we highly recommend checking out some of the top attractions.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Parco Regionale Migliarino, San Rossore, Massaciuccoli, a worthwhile nature reserve that everyone visiting Cascine Vecchie should see.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Treat yourself to an extraordinary dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an incredible italian contemporary menu. Alternatively, if your taste buds call for something different, Santa Elisabetta is one of the best restaurants for creative and mediterranean cuisine in Florence. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gucci Osteria da Massimo Bottura. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary and international cuisine in the city.

Unwind after your meal by stepping into Manifattura. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Se·sto On Arno Rooftop Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Il Vinile, another top-rated bar in the area.

Savor another day of unforgettable experiences in Italy!

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Day9

Day 9

  • Florence
  • More

Drive 4 km, 1 hour 6 min

  • piazzale Michelangelo
  • Uffizi Gallery
  • Ponte Vecchio
  • piazza della Signoria
  • Cathedral of Santa Maria del Fiore
  • More

On day 9 of your road trip, you will have an entire day to discover what to see in Florence. You’ll stay in Florence for 1 night.

Let Piazzale Michelangelo set the tone for the day. Spend some time admiring this romantic observation deck before continuing your journey. Uffizi Gallery is your next stop. This impressive art gallery is one of the best-rated sights in Florence.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Ponte Vecchio. This culturally significant historical landmark is a sight to behold. To round off your sightseeing experience, visit Piazza Della Signoria and Cathedral Of Santa Maria Del Fiore.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Ditta Artigianale, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Da Burde? It's another excellent option with a diverse menu. Consider reserving a table at Casa Toscana as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.

If you’re not ready to end the night just yet, Bar 50 Rosso offers a perfect venue to relax and savor a drink. Similarly, Bitter Bar is well-suited for those looking to unwind in a social setting. Archea Brewery is another excellent spot to enjoy a nightcap after a delightful meal.

Celebrate another amazing day of your road trip adventure in Italy!

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Day10

Day 10

  • Florence
  • Vatican City
  • Rome
  • More

Drive 285 km, 3 hours 57 min

  • Sistine Chapel
  • St Peter's Basilica
  • Saint Peter's Square
  • Vatican Museums
  • More

On day 10 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Vatican City. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 1 night.

Continue your road trip and head to your next destination, Vatican City, Vatican City. This car ride takes around 3 hours 14 min.

One of our top recommendations for your sightseeing is Sistine Chapel. Then, head to St. Peter's Basilica. This wondrous major basilica is a traveler-favorite in the city.

If you're keen to see more, continue to Saint Peter's Square. Feed your curiosity by learning something new about the square. Next, take your journey to Vatican Museums, a globally renowned art museum.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Ristorante Va. Do. , an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Giulia Restaurant, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of L'Archeologia, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Relax and recharge in preparation for another adventurous day in Italy!

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Day11

Day 11

  • Rome - Departure day
  • More
  • Orange Garden
  • More

Day 11 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Orange Garden. This captivating park is a hotspot among locals.

Take advantage of your accommodation's proximity to Rome’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

Enjoy a lovely meal at Caffè Antica Roma, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Maccheroni is another top choice with a popular menu.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
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From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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