10-Day Italy Self-Drive Road Trip With Itinerary from Venice traveling south to Florence, Rome, and Siena

Day 2 of your road trip across Italy promises a magnificent time exploring what to see in Venice. You have 1 night left in Venice. Take the opportunity to experience more of the best attractions and activities in the city.

Enjoy all that Peggy Guggenheim Collection has to offer. This is a well-known art gallery you should not miss. Another must-see is Teatro La Fenice, a locally renowned opera house in Venice.

When you’re ready for the next sight, head to Piazza San Marco. From there, take a leisurely stroll to St Mark's Basilica, another of the city’s locally renowned attractions. We recommend continuing your self-guided tour at Doge's Palace, a grand place of interest in the city. If time allows, add Bridge Of Sighs to your itinerary. This popular monument offers the perfect finishing touch to your day in Venice.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

For an unforgettable shopping experience, visit Rialto Market, the top shopping destination in Venice. Browse local shops and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Rialto Market has to offer, including attractions, essential services, and vibrant community activities.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Venice. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Generator Venice, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Nevodi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

After savoring a delicious meal, step into the vibrant nightlife at Il Mercante, where the evening is just getting started. In the same way, The Irish Pub Venezia offers a unique charm perfect for experiencing the local bar scene in Venice. Ai Stagneri is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Relax and recharge in preparation for another adventurous day in Italy!

On day 3 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Florence. This drive usually takes around 2 hours 56 min, without any stops or traffic disruptions.

Our first attraction recommendation in Florence is Basilica Of Santa Croce In Florence, a notable church that draws attention for its culturally significant features. Spend some time soaking in the atmosphere before continuing to Uffizi Gallery, a historic art gallery that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Ponte Vecchio, a wondrous historical landmark that offers a unique experience. Be sure to also explore Loggia Dei Lanzi, a nearby public square, highly recommended by other travelers. End your self-guided tour at Palazzo Vecchio, a history-steeped palace and the perfect final attraction in Florence.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Following your dinner, dive into the local bar culture at Manifattura. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Se·sto On Arno Rooftop Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Il Vinile provides excellent drinks and a great atmosphere, ensuring a memorable night out.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 4 of your road trip, you’ll start and end your day in Florence, where you have 1 night left to stay.

Enjoy all that Galleria Dell'accademia has to offer. This is a popular art gallery you should not miss. Another must-see is Museo Dell'opera Del Duomo, an underrated museum in Florence.

When you’re ready for the next sight, head to Florence Baptistery.

When you’re ready to jump back into the car and say goodbye to Florence, you’ll hit the road in the direction of Pisa. This drive usually takes around 1 hour 14 min.

Savor the day by heading to Leaning Tower Of Pisa, an iconic monument that draws visitors from near and far. When you're done, continue to Piazza Del Duomo, Pisa, where you can soak in the breathtaking surroundings.

Next, explore Battistero Di San Giovanni, yet another intriguing place to see in the area.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar 50 Rosso, a well-loved spot among locals and tourists. Or, head to Bitter Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Archea Brewery, another top-rated place in the area.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Your itinerary for day 5 of your road trip in Italy includes 2 stops and features some of the highlights of Orvieto and Rome. At the end of the day, enjoy the comforts of a top-rated hotel in Rome, where you'll spend 3 nights.

Continue your road trip and head to your next destination, Orvieto. This car ride takes around 1 hour 58 min.

Set out on a self-guided sightseeing tour at Orvieto Cathedral and explore the romantic features.

Fasten your seatbelt and make your way to your next stop — Rome, home to many well-known sights in the region. Keep in mind that your travel time from Orvieto to Rome may take around 1 hour 30 min without traffic disruptions. Upon arrival in Rome, we highly recommend checking out some of the top attractions.

Savor the day by heading to Spanish Steps, an astonishing public square that draws visitors from near and far. When you're done, continue to Piazza Di Spagna, where you can soak in the enchanting surroundings.

Next, explore Trevi Fountain, yet another iconic place to see in the area. After the monument, make time to go to Pantheon. This photogenic monument is well worth the visit. Lastly, head to Circus Maximus, a locally renowned archeological site you won’t want to miss.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Rome. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely meal at La Bottega Roma, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Pasta In Corso is another top choice with a popular menu. You could also check for a table at Trattoria Vecchia Roma. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Rome tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at La Botticella Of Poggi Giovanni, a well-loved spot among locals and tourists. Or, head to Almalu Trastevere. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Viminale Di Pepi Maurilio, another top-rated place in the area.

Head back to your accommodation in Rome and get some rest to prepare for another magical day of your road trip in Italy.

Day 6 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Rome.

Make time for Colosseum, a globally renowned archeological site that is worthwhile a visit in the city. Nearby, you’ll find Roman Forum, enchanting visitors with its picture-perfect appeal. Continue your exploration at Altare Della Patria. This monument is one of the city’s most interesting spots.

Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Campo De' Fiori. After exploring the public square, head to the iconic Piazza Navona. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Castel Sant'angelo, a place of enchanting interest in Rome.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to Sant' Eustachio Caffè, ideal for a leisurely evening with a drink in hand. Yellowsquare Rome is another bar that offers an enjoyable setting. Similarly, Caffè Portofino is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 7 of your road trip, you’ll start and end your day in Rome, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Vatican City and Rome.

Trastevere is one of the highlights of today. Take your time exploring this iconic neighborhood in Vatican City, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Awaiting your discovery is the spectacular Piazza Del Popolo, a symbolic public square in Rome.

Upon reaching Vatican City, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

St. Peter's Basilica is a timeless major basilica we recommend visiting today.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Savor the flavors at Hotel de Russie, a top pick for dinner tonight. Alternatively, La Taverna Italiana beckons with its unique menu offerings. Also, consider The Parrot Bar. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Keep the excitement of the evening going by visiting a bar or two. The Apartment Bar Roma is an excellent place to start. You could also check out Hotel Hassler Roma, offering a different kind of charm.

Head back to your accommodation in Rome and get some rest to prepare for another magical day of your road trip in Italy.

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Siena. At the end of the day, you will retreat to the hotel of your choice in Siena, where will spend 1 night.

After soaking in Rome’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Siena. Expect your car journey to take a minimum of 2 hours 45 min. When you arrive in Siena, it's time to take a break from the road.

Porta Camollia, Siena is a frequently visited monument we recommend visiting today. Discover its picture-perfect features before continuing your self-guided tour to Basilica Of San Domenico, a stunning church that’s well-regarded in the area.

Next, stop by Siena Cathedral, an enchanting church. While you’re nearby, don’t forget to visit Pubblico Palace, a picture-perfect and truly unique palace. End your sightseeing at Piazza Del Campo, an extraordinary public square that’s highly recommended by travelers passing through the city.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Enoteca I Terzi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Tar-Tufo? It's another excellent option with a diverse menu. Consider reserving a table at Antica Trattoria Papei as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.

After enjoying a fulfilling meal, continue your evening at Meet Life Cafè, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Maudit Pub offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Impero Siena provides an excellent environment for a relaxed and enjoyable evening.

Savor another day of unforgettable experiences in Italy!

Dive into day 9 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Bologna. At the end of the day, you’ll unwind at one of the finest accommodations in Venice, where you'll spend 1 night.

Bologna’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Siena behind. This drive usually takes around 2 hours 1 min. Bologna welcomes you with a multitude of unique vacation experiences.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Palazzo Pallavicini, an increasingly popular palace that everyone visiting Bologna should see. Next, head to Chiesa Del Santissimo Salvatore. This photogenic church is one of the most intriguing attractions in the region.

If you're keen to see more, don’t miss out on Piazza Maggiore, a symbolic public square popular among locals as well as travelers. Two Towers is an excellent attraction to visit next. Spend some time learning more about this locally renowned monument before you continue your journey. Lastly, visit Bologna Cathedral, a historic church and a top attraction in the city.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Venice is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Venice.

Savor the flavors at Osteria Alla Staffa, a top pick for dinner tonight. Alternatively, Bistrot de Venise beckons with its unique menu offerings. Also, consider Corte Sconta. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Dolce Vita Venezia stands out as an excellent choice for a post-dinner cocktail. Alternatively, Tarnowska's American Bar offers an ideal atmosphere to enjoy the pleasures of the night. Bar All'angolo is also a great option that provides a perfect setting for a relaxing evening.

Relax and look forward to more memorable moments to come!