10-Day Italy Self-Drive Road Trip With Itinerary from Venice to Florence, Lucca, San Gimignano, and Rome

Greet day 2 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Venice, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Venice and Murano.

Piazza San Marco is an ideal stop early in the day. This world-famous public square is a must-visit in the city. When you’re ready for your next discovery, continue to St Mark's Campanile, which may be one of the most UNESCO world heritage-designated places you will experience today.

One of the best things about exploring Venice on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to St Mark's Basilica, a popular church in the city. If you’re up for more discoveries, don’t forget to reserve some time for Doge's Palace and Bridge Of Sighs.

Murano’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Venice behind. This drive usually takes around 1 min. Murano welcomes you with a multitude of unique vacation experiences.

Spend your afternoon discovering Murano, a curiosity-inducing handicraft store known for its romantic features.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Venice.

Venice is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Venice.

Enjoy a delicious meal at Generator Venice, a highly-rated dining destination in Venice. If you're eager to try something different, consider Nevodi, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Venice this evening.

Following your dinner, dive into the local bar culture at Il Mercante. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to The Irish Pub Venezia, the perfect place for those looking to experience the best of the nightlife. Similarly, Ai Stagneri provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Head back to your accommodation in Venice and get some rest to prepare for another magical day of your road trip in Italy.

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Florence. At the end of the day, you will retreat to the hotel of your choice in Florence, where will spend 1 night.

Embrace the thrill of the open road as you wave goodbye to Venice and set your GPS to Florence. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 52 min. Upon reaching Florence, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Savor the day by heading to Ponte Vecchio, an iconic historical landmark that draws visitors from near and far. When you're done, continue to Uffizi Gallery, where you can soak in the romantic surroundings.

Next, explore Basilica Of Santa Croce In Florence, yet another interesting place to see in the area. After the church, make time to go to Hercules And Cacus. Lastly, head to Piazza Della Signoria, an extraordinary public square you won’t want to miss.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Florence is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Florence.

Treat yourself to a wonderful meal at Ristorante Oliviero 1962, a top-rated dining spot in Florence. If you're in the mood for something new, try Di Poneta Novoli, another premier location with a delectable menu. You might also want to book a table at Caffe San Firenze. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Florence.

Continue the enjoyment post-dinner at Manifattura, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Se·sto On Arno Rooftop Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Il Vinile. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

On day 4 of your road trip in Italy, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Florence, Pisa, and Lucca are on today's agenda. In the evening, you’ll end up in Lucca, where you will stay for 2 nights.

To truly experience Florence, make sure to drop by Cathedral Of Santa Maria Del Fiore. This spectacular church is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Galleria Dell'accademia, one of the city’s best highlights.

Continue your road trip and head to your next destination, Pisa. This car ride takes around 1 hour 19 min.

When you're ready for some sights, head to Piazza Del Duomo, Pisa, a timeless public square in Pisa. Explore its historic features at your own pace before you continue your journey to your next attraction, Leaning Tower Of Pisa. This wondrous monument is a top recommendation in the area.

Set your GPS to Lucca and hit the road. Expect a journey of approximately 31 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Lucca beckons with new experiences!

Our first attraction recommendation in Lucca is Mura Di Lucca, a locally appreciated historical landmark that draws attention for its romantic features.

When you’re done exploring for the day, you’ll drive to your hotel in Lucca. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Lucca's most popular restaurants, and connect with friendly locals for a true cultural experience.

Dine in style at Gli Orti di Via Elisa, a top recommendation for dinner tonight. Or, for a change of pace, Bar Caffè Ristretto boasts a menu that's sure to impress. Also, be sure to check out Ristorante Schiaffino. Known as a local hotspot, it’s a great choice for tonight in Lucca.

Extend your evening after a delightful meal by visiting Lebowski - Cocktail Bar, which offers the perfect atmosphere for a night out. Moreover, Blend is another popular option for a drink or two. Likewise, Franklin'33 also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Get a good night's sleep and look forward to another great day on the road in Italy!

On day 5 of your road trip, you’ll start and end your day in Lucca, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Riomaggiore, Manarola, Corniglia, and Levanto.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Riomaggiore may take around 1 hour 22 min. Upon your arrival in Riomaggiore, you’ll be greeted with the opportunity to do some sightseeing and exploring.

For a more meaningful self-guided tour of the village's best attractions, visit Riomaggiore, an increasingly popular sightseeing destination that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

Continue your road trip and head to your next destination, Corniglia. This car ride takes around 15 min.

Set out on a self-guided sightseeing tour at Manarola Overlook Viewpoint and explore the eye-catching features.

Embrace the thrill of the open road as you wave goodbye to Manarola and set your GPS to Corniglia. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 15 min. Upon reaching Corniglia, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Cinque Terre National Park, a captivating national park that everyone visiting Corniglia should see.

When you’re done exploring for the day, you’ll return to Lucca and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lucca. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at Osteria Nova, an iconic dining spot in Lucca. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Bottega di Anna e Leo, a popular restaurant in Lucca. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Ristorante Per 21, a hidden gem nestled in Lucca. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your evening by exploring the vibrant nightlife scene at La Tana Del Boia, a prime destination for a thrilling night out. Also, don’t forget to check out Vinarkia Della Pavona - Cocktail Bar, a bar that offers unique local touches. Likewise, Magellano provides an excellent alternative for a fun evening.

Relax and recharge in preparation for another adventurous day in Italy!

Your itinerary for day 6 of your road trip in Italy includes 2 stops and features some of the highlights of Siena and San Gimignano. At the end of the day, enjoy the comforts of a top-rated hotel in San Gimignano, where you'll spend 1 night.

As you explore Siena’s charming streets, take in the lively atmosphere and get to know the character of the city.

Siena’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Lucca behind. This drive usually takes around 1 hour 44 min. Siena welcomes you with a multitude of unique vacation experiences.

Spend your afternoon discovering Siena Cathedral, an interesting church known for its culturally significant features. Next, continue your sightseeing at Pinacoteca Nazionale, a worthwhile art gallery.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Piazza Del Campo and uncover the details of this UNESCO world heritage-listed public square. Make sure to also explore Tower Of Mangia, an often recommended monument.

After soaking in Siena’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: San Gimignano. Expect your car journey to take a minimum of 47 min. When you arrive in San Gimignano, it's time to take a break from the road.

Set out on a self-guided sightseeing tour at Parco Della Rocca and explore the romantic features. Next, make your way to Piazza Del Duomo, another highlight in San Gimignano.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in San Gimignano. San Gimignano offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in San Gimignano. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Rome. When you’re not sightseeing, take time to relax at your chosen hotel in Rome, where you’ll be staying for 2 nights.

Continue your road trip and head to your next destination, Rome. This car ride takes around 3 hours 8 min.

Our first attraction recommendation in Rome is Castel Sant'angelo, a top-rated castle that draws attention for its culturally significant features. Spend some time soaking in the atmosphere before continuing to Piazza Navona, a visually striking public square that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Pantheon, a globally renowned monument that offers a unique experience. Be sure to also explore Trevi Fountain, a nearby monument, highly recommended by other travelers. End your self-guided tour at Piazza Di Spagna, a grand public square and the perfect final attraction in Rome.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at La Botticella Of Poggi Giovanni, a well-loved spot among locals and tourists. Or, head to Almalu Trastevere. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Viminale Di Pepi Maurilio, another top-rated place in the area.

Relax and look forward to more memorable moments to come!

On day 8 of your road trip, you'll get the chance to experience Vatican City and Rome. At the end of the day, you'll drive back to Rome, where you still have 1 night left to stay.

Colosseum is perfect for a self-paced visit during the day. This UNESCO world heritage-designated archeological site is sure to impress. Next on your list is Roman Forum, another must-visit landmark and timeless archeological site renowned for its historic features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Capitoline Hill. This culturally significant public square is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Altare Della Patria, an interesting monument. Nearby, you'll also find Archbasilica Of St. John Lateran, ready to add charm to your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Rome.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a wonderful meal at RomAntica, a top-rated dining spot in Rome. If you're in the mood for something new, try Coso Ristorante, another premier location with a delectable menu. You might also want to book a table at DEROMA - Farine Romane. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Rome.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Sant' Eustachio Caffè, known for its inviting atmosphere. Yellowsquare Rome is another great option if you’re looking for a place to get the night started. Similarly, Caffè Portofino provides a great setting to enjoy the night away.

Relax and look forward to more memorable moments to come!

Dive into day 9 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Santa Maria degli Angeli. At the end of the day, you’ll unwind at one of the finest accommodations in Venice, where you'll spend 1 night.

After soaking in Rome’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Santa Maria degli Angeli. Expect your car journey to take a minimum of 2 hours 28 min. When you arrive in Santa Maria degli Angeli, it's time to take a break from the road.

When you're ready for some sights, head to Piazza Del Comune, an intriguing public square in Santa Maria degli Angeli. Explore its visually striking features at your own pace before you continue your journey to your next attraction, Portico Of Monte Frumentario. This increasingly popular historical landmark is a top recommendation in the area.

When you’re ready to explore more, Basilica Of San Francesco D'assisi is an excellent choice. Spend some time discovering what some claim to be the most historic church in the region.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Venice. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Osteria Alla Staffa, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Bistrot de Venise offers an enticing alternative with its varied menu. Additionally, Corte Sconta is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Venice.

Let the evening flow smoothly from dinner to drinks at Dolce Vita Venezia, a top-rated bar in the area. For other recommendations, Tarnowska's American Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar All'angolo offers a memorable night with diverse drink options and excellent service.

Relax and recharge in preparation for another adventurous day in Italy!