10-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling north to Florence, Siena, La Spezia, and Venice

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Colosseum, Rome, Italy.
Photo of piazza de spagna in Rome, Italy.
10-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling north to Florence, Siena, La Spezia, and Venice
10-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling north to Florence, Siena, La Spezia, and Venice
10-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling north to Florence, Siena, La Spezia, and Venice
10-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling north to Florence, Siena, La Spezia, and Venice
10-Day Italy Self-Drive Road Trip With Itinerary from Rome traveling north to Florence, Siena, La Spezia, and Venice
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Experience the freedom of the open road on an unforgettable 10-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Rome, Florence, Pisa, Siena, Castellina in Chianti, Corniglia, Manarola, Riomaggiore, La Spezia, Venice, and Verona.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 3 nights in Rome, 2 nights in Florence, 2 nights in Siena, 1 night in La Spezia, and 1 night in Venice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Rome, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Rome, Florence, Pisa, Siena, Castellina in Chianti, Corniglia, Manarola, Riomaggiore, La Spezia, Venice, and Verona, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day1

Day 1

  • Rome - Arrival day
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  • Palatine Hill
  • More

Your road trip adventure in Italy begins as soon as you reach Rome and pick up your car. You’ll stay here for 2 nights and explore what to see in Rome, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Rome is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Palatine Hill. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Rome. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at La Bottega Roma, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Pasta In Corso, another top spot with a mouthwatering menu. You might also want to secure a reservation at Trattoria Vecchia Roma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

Extend your evening after a delightful meal by visiting La Botticella Of Poggi Giovanni, which offers the perfect atmosphere for a night out. Moreover, Almalu Trastevere is another popular option for a drink or two. Likewise, Bar Viminale Di Pepi Maurilio also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise a toast to the start of your 10-day road trip in Italy!

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Day2

Day 2

  • Rome
  • More

Drive 6 km, 1 hour 24 min

  • Colosseum
  • Roman Forum
  • Trevi Fountain
  • Spanish Steps
  • Piazza Navona
  • Trastevere
  • More

Day 2 of your road trip across Italy promises a magnificent time exploring what to see in Rome. You have 1 night left in Rome. Take the opportunity to experience more of the best attractions and activities in the city.

Trastevere is one of the highlights of today. Take your time exploring this iconic neighborhood in Rome, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Colosseum makes a great addition to your morning plans. This globally renowned archeological site is a picture-perfect place to see in Rome. Continue your discovery at Roman Forum, a breathtaking archeological site with stories to tell.

As you stroll around Rome, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Trevi Fountain. This timeless monument offers a visually striking encounter with Rome. Next, make your way to Spanish Steps to add another highlight to your day. After that, visit Piazza Navona, an iconic public square that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Rome's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Sant' Eustachio Caffè, known for its inviting atmosphere. Yellowsquare Rome is another great option if you’re looking for a place to get the night started. Similarly, Caffè Portofino provides a great setting to enjoy the night away.

Say good night to Rome and look forward to another great day of your road trip in Italy!

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Day3

Day 3

  • Rome
  • Florence
  • More

Drive 281 km, 3 hours 51 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Piazza della Repubblica
  • piazza della Signoria
  • More

On day 3 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Florence may take around 3 hours 6 min. Upon your arrival in Florence, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Piazzale Michelangelo is an astonishing observation deck we recommend visiting today. Discover its history-steeped features before continuing your self-guided tour to Basilica Of Santa Croce In Florence, an inviting church that’s well-regarded in the area.

Next, stop by Uffizi Gallery, a romantic art gallery. While you’re nearby, don’t forget to visit Ponte Vecchio, a symbolic and truly unique historical landmark. End your sightseeing at Piazza Della Repubblica, a locally renowned public square that’s highly recommended by travelers passing through the city.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Ristorante Oliviero 1962, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Di Poneta Novoli offers an enticing alternative with its varied menu. Additionally, Caffe San Firenze is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Following your dinner, dive into the local bar culture at Manifattura. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Se·sto On Arno Rooftop Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Il Vinile provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Relax and look forward to more memorable moments to come!

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Day4

Day 4

  • Florence
  • Pisa
  • More

Drive 196 km, 3 hours 5 min

  • Palazzo Blu
  • Knights' Square
  • Palazzo della Carovana
  • Leaning Tower of Pisa
  • Pisa Cathedral
  • Piazza del Duomo, Pisa
  • More

On day 4 of your road trip in Italy, you’ll start and end your day in Florence, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Florence, there’s no need to rush. Experience Pisa to the fullest today with this curated day itinerary.

Continue your road trip and head to your next destination, Pisa. This car ride takes around 1 hour 13 min.

For a more meaningful self-guided tour of the city's best attractions, visit Palazzo Blu, a beloved art gallery that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Knights' Square and admire its stunning features.

When you’re ready, continue to Palazzo Della Carovana, a frequently visited palace beloved by locals and tourists alike. Don't miss out on Leaning Tower Of Pisa, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Pisa Cathedral, a breathtaking place to see that you won’t regret spending some extra time discovering.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Don’t miss out on dining at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Let the evening flow smoothly from dinner to drinks at Bar 50 Rosso, a top-rated bar in the area. For other recommendations, Bitter Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Archea Brewery offers a memorable night with diverse drink options and excellent service.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day5

Day 5

  • Florence
  • Siena
  • More

Drive 79 km, 1 hour 28 min

  • Basilica of San Domenico
  • Fontebranda
  • Siena Cathedral
  • Pubblico Palace
  • piazza del Campo
  • Tower of Mangia
  • More

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Siena. At the end of the day, you will retreat to the hotel of your choice in Siena, where will spend 2 nights.

After soaking in Florence’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Siena. Expect your car journey to take a minimum of 1 hour 8 min. When you arrive in Siena, it's time to take a break from the road.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Basilica Of San Domenico, a frequently visited church that everyone visiting Siena should see. Next, head to Fontebranda. This symbolic historical landmark is one of the most underrated attractions in the region.

If you're keen to see more, don’t miss out on Siena Cathedral, a romantic church popular among locals as well as travelers. Pubblico Palace is an excellent attraction to visit next. Spend some time learning more about this intriguing palace before you continue your journey. Lastly, visit Piazza Del Campo, a visually striking public square and a top attraction in the city.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Siena, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Enoteca I Terzi, a highly-rated dining destination in Siena. If you're eager to try something different, consider Ristorante Tar-Tufo, another top spot with a tantalizing menu. You might also want to secure a reservation at Antica Trattoria Papei. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Siena this evening.

Cap off your dinner by heading to Meet Life Cafè, ideal for a leisurely evening with a drink in hand. Maudit Pub is another bar that offers an enjoyable setting. Similarly, Bar Impero Siena is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day6

Day 6

  • Siena
  • Castellina in Chianti
  • More

Drive 76 km, 2 hours 7 min

  • Winery San Giorgio a Lapi
  • Castello di Brolio
  • Poggio Amorelli
  • Tumulo di Montecalvario
  • Rocca di Castellina in Chianti
  • More

On day 6 of your road trip, you’ll start and end your day in Siena, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Siena, San Regolo, and Castellina in Chianti.

Awaiting your discovery is the often recommended Winery San Giorgio A Lapi, a visually striking winery in Siena.

Continue your road trip and head to your next destination, San Regolo. This car ride takes around 26 min.

Savor the day by heading to Castello Di Brolio, an increasingly popular castle that draws visitors from near and far.

Castellina in Chianti’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of San Regolo behind. This drive usually takes around 40 min. Castellina in Chianti welcomes you with a multitude of unique vacation experiences.

Poggio Amorelli is an up-and-coming winery we recommend visiting today. Discover its awe-inspiring features before continuing your self-guided tour to Tumulo Di Montecalvario, a heritage-rich archeological site that’s well-regarded in the area.

Next, stop by Rocca Di Castellina In Chianti, a romantic castle.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Siena.

Siena is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Siena.

Treat yourself to a wonderful meal at Osteria Quattro Venti, a top-rated dining spot in Siena. If you're in the mood for something new, try Fischi per Fiaschi, another premier location with a delectable menu. You might also want to book a table at Osteria da Divo. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Siena.

Cap off your dinner by heading to Charlie Mixology Bar Di Aldinucci Riccardo, ideal for a leisurely evening with a drink in hand. Bar Pinacoteca is another bar that offers an enjoyable setting. Similarly, San Paolo Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Celebrate another amazing day of your road trip adventure in Italy!

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Day7

Day 7

  • Siena
  • Corniglia
  • Manarola
  • Riomaggiore
  • La Spezia
  • More

Drive 259 km, 4 hours 21 min

  • Cinque Terre National Park
  • Manarola Overlook Viewpoint
  • Chiesa di San Lorenzo
  • Riomaggiore
  • More

Your itinerary for day 7 of your road trip in Italy includes 3 stops and features some of the highlights of Corniglia, Manarola, and Riomaggiore. At the end of the day, enjoy the comforts of a top-rated hotel in La Spezia, where you'll spend 1 night.

Continue your road trip and head to your next destination, Corniglia. This car ride takes around 2 hours 56 min.

Spend your afternoon discovering Cinque Terre National Park, a well-known national park known for its romantic features.

Set your GPS to Manarola and hit the road. Expect a journey of approximately 15 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Manarola beckons with new experiences!

Set out on a self-guided sightseeing tour at Manarola Overlook Viewpoint and explore the eye-catching features. Next, make your way to Chiesa Di San Lorenzo, another highlight in Manarola.

When you’re done exploring for the day, you’ll drive to your hotel in La Spezia. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of La Spezia's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at The Colombaio Park, highly recommended for tonight's dining.

Celebrate another amazing day of your road trip adventure in Italy!

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Day8

Day 8

  • La Spezia
  • Venice
  • More

Drive 366 km, 4 hours 32 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Grand Canal
  • Rialto Bridge
  • More

On day 8 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Venice. When you’re not sightseeing, take time to relax at your chosen hotel in Venice, where you’ll be staying for 1 night.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Venice. This drive usually takes around 4 hours 12 min, without any stops or traffic disruptions.

When you're ready for some sights, head to Bridge Of Sighs, a notable monument in Venice. Explore its history-steeped features at your own pace before you continue your journey to your next attraction, Doge's Palace. This notable palace is a top recommendation in the area.

When you’re ready to explore more, St Mark's Basilica is an excellent choice. Spend some time discovering what some claim to be the most majestic church in the region. Next, continue your sightseeing at the frequently visited Grand Canal and discover what makes this street unique. If you’re up for one more stop in the city, head to Rialto Bridge, a romantic historical landmark many travelers find the visit worthwhile.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Venice is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Venice.

Enjoy a delicious meal at Bauer Hotel, a top-rated dining destination in Venice. If you're in the mood to try something new, consider L'Osteria Le Guglie, another top spot with a mouthwatering menu. You might also want to secure a reservation at Corner Pub. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

After savoring a delicious meal, step into the vibrant nightlife at Al Parlamento, where the evening is just getting started. In the same way, The Caffe Rosso offers a unique charm perfect for experiencing the local bar scene in Venice. Adagio is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Relax and recharge in preparation for another adventurous day in Italy!

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Day9

Day 9

  • Venice
  • Verona
  • Rome
  • More

Drive 632 km, 7 hours 4 min

  • Ponte Pietra
  • Scaliger Tombs
  • piazza delle Erbe
  • Verona Arena
  • More

Dive into day 9 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Verona. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 1 night.

When you’ve had your share of Venice, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Verona. Your travel time is around 1 hour 23 min.

Set out on a self-guided sightseeing tour at Ponte Pietra and explore the symbolic features. Next, make your way to Scaliger Tombs, another highlight in Verona. When you’re done exploring the monument, continue to Piazza Delle Erbe, an awe-inspiring public square.

Nearby, you will also find Verona Arena. This wondrous stadium is a top place to see in the area.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Make sure to reserve a table at Hotel de Russie, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of La Taverna Italiana, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of The Parrot Bar, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting The Apartment Bar Roma after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Hotel Hassler Roma, another bar with an inviting ambiance.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day10

Day 10

  • Rome - Departure day
  • More
  • Pantheon
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Rome before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Pantheon, a heritage-rich monument before you head out.

Take some time to indulge in shopping at Rome’s popular marketplace, Via del Corso. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Rome.

Have a fantastic dining experience at Sofitel Roma Villa Borghese, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Centro offers an enticing alternative with its varied menu.

You’ll then say farewell to Rome. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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