7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Veria, Ioannina, and Trikala

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Photo of bird's eye view to the promenade of Thessaloniki.
Photo of Saint Paul cathedral in Thessaloniki, Greece.
7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Veria, Ioannina, and Trikala
7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Veria, Ioannina, and Trikala
7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Veria, Ioannina, and Trikala
7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Veria, Ioannina, and Trikala
7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Veria, Ioannina, and Trikala
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Experience the freedom of the open road on an unforgettable 7-day road trip in Greece! Embark on a self-drive tour that caters to every traveler, featuring destinations like Thessaloniki, Edessa, Veria, Metsovo, Mandio, Ioannina, Perama, Neo Bizani, Trikala, and Kastraki.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Thessaloniki, 1 night in Veria, 1 night in Ioannina, and 1 night in Trikala. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Thessaloniki, Edessa, Veria, Metsovo, Mandio, Ioannina, Perama, Neo Bizani, Trikala, and Kastraki, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
  • More

Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay here for 2 nights and explore what to see in Thessaloniki, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Thessaloniki. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Kitchen Bar, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, The Greek is another top choice with a popular menu. You could also check for a table at Phanós. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Thessaloniki tonight.

Keep the evening going at Beetle Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Vogatsikou 3, which offers a similarly pleasant setting and great drinks. Another option is Souel, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 7-day road trip in Greece!

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Day2

Day 2

  • Thessaloniki
  • More

Drive 6 km, 55 min

  • The Umbrellas by Zongolopoulos
  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Aristotelous Square
  • Tsimiski Street
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Thessaloniki. You’ll stay in Thessaloniki for 1 night.

A top thing to do today is to explore Tsimiski Street, a must-see street in Thessaloniki. It's the perfect starting point for touring the top attractions in the area.

Catch The Umbrellas Sculpture By Zogolopoulos before the crowds roll in. This enchanting art installation is sure to ignite your curiosity. Next, dive into the photogenic features of Archaeological Museum Of Thessaloniki, a must-visit museum in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to White Tower Of Thessaloniki, a spectacular monument. For a change of scene, check out Aristotelous Square, known for its awe-inspiring features.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Thessaloniki. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor the flavors at Mamalouka, a top pick for dinner tonight. Alternatively, Clochard beckons with its unique menu offerings. Also, consider Sofi's House Restaurant. With its consistent customer satisfaction, it’s an excellent option for dining in Thessaloniki tonight.

After savoring a delicious meal, step into the vibrant nightlife at Castra- All Day Terrace Bar, where the evening is just getting started. In the same way, Barbaben - Bar/ba/ben offers a unique charm perfect for experiencing the local bar scene in Thessaloniki. Apallou is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day3

Day 3

  • Thessaloniki
  • Edessa
  • Veroia
  • More

Drive 131 km, 2 hours 50 min

  • Kapani
  • Church of St Demetrios
  • Atatürk Museum
  • Arch of Galerius
  • Edessa Waterfalls
  • More

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, including Thessaloniki and Edessa. When you’re not sightseeing, take time to relax at your chosen hotel in Veria, where you’ll be staying for 1 night.

To truly experience Thessaloniki, make sure to drop by Kapani. This locally renowned market is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Holy Church Of Saint Demetrius, Patron Saint Of Thessalonica, one of the city’s best highlights.

Next, check out Atatürk Museum, one of the most curiosity-inducing places to see in Thessaloniki. This museum is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Arch Of Galerius And Rotunda. Wander around and soak in the culturally significant atmosphere this monument offers.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Edessa may take around 1 hour 23 min. Upon your arrival in Edessa, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Savor the day by heading to Waterfalls Park, Edessa, a well-known waterfall that draws visitors from near and far.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Veria. Veria offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Veria. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Plátanos, a popular restaurant in Veria. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Veria at Psaropoúla, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Stasoy Mygdala. It’s yet another ideal choice to enhance your time in Veria tonight.

After savoring a delicious meal, step into the vibrant nightlife at Kochlías, where the evening is just getting started. In the same way, Floretta Cafe Bar offers a unique charm perfect for experiencing the local bar scene in Veria. Delante Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Relax and look forward to more memorable moments to come!

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Day4

Day 4

  • Veroia
  • Metsovo
  • Mandio
  • Ioannina
  • More

Drive 246 km, 3 hours 37 min

  • Anilio Ski Center
  • Αβερώφειος Κήπος
  • Metsovo square
  • Averoff Art Gallery
  • Archaeological Site of Dodoni
  • More

Experience an unparalleled adventure on day 4 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Metsovo and Mandio. At the end of the day, you will retreat to the hotel of your choice in Ioannina, where will spend 1 night.

Throughout the day, make sure to take breaks to appreciate the surroundings.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Mandio. This drive usually takes around 44 min, without any stops or traffic disruptions.

Anilio Ski Center is an intriguing ski resort we recommend visiting today. Discover its visually striking features before continuing your self-guided tour.

When you’ve had your share of Metsovo, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Mandio. Your travel time is around 44 min.

Set out on a self-guided sightseeing tour at Averofeios Kipos and explore the serene features. Next, make your way to Metsovo Square, another highlight in Metsovo. When you’re done exploring the public square, continue to Averoff Art Gallery, a visually striking art gallery.

Embrace the thrill of the open road as you wave goodbye to Metsovo and set your GPS to Mandio. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 44 min. Upon reaching Mandio, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Archaeological Site Of Dodoni. Spend some time admiring the picture-perfect features of the archeological site before you continue to your next stop.

When you’re done exploring for the day, you’ll drive to your hotel in Ioannina. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Ioannina. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at To Dodeka Cafe Bar, an iconic dining spot in Ioannina. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mustagogia, a popular restaurant in Ioannina. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Accademia Del Panino, a hidden gem nestled in Ioannina. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Let the evening flow smoothly from dinner to drinks at ⚜ V E D E M A ⚜, a top-rated bar in the area. For other recommendations, Hogwarts Tales And Spirits provides a perfect setting for rounding out your night with style and great drinks. Likewise, Chevalier offers a memorable night with diverse drink options and excellent service.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day5

Day 5

  • Ioannina
  • Perama
  • Neo Bizani
  • Trikala
  • More

Drive 153 km, 3 hours 1 min

  • The Clock Tower of Ioannina
  • Ioannina Castle
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • Vrellis Greek History Museum (Wax Museum)
  • More

On day 5 of your road trip in Greece, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Ioannina, Perama, and Neo Bizani are on today's agenda. In the evening, you’ll end up in Trikala, where you will stay for 1 night.

The Clock Tower Of Ioannina brings Ioannina's character to life. This historic monument is a highlight of any visit in the city. Then, enjoy Ioannina Castle, another history-steeped attraction that never fails to captivate visitors. Next, head over to Ic Kale Acropolis Of Ioannina, one of the city’s most worthwhile attractions, known for its standout features.

Set your GPS to Perama and hit the road. Expect a journey of approximately 11 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Perama beckons with new experiences!

Our first attraction recommendation in Perama is Cave Of Perama, an increasingly popular cave that draws attention for its eye-catching features.

When you’ve had your share of Perama, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Neo Bizani. Your travel time is around 30 min.

When you're ready for some sights, head to Moyseio Ellinikis Istorias Payloy Vrelli, a locally appreciated museum in Neo Bizani. Explore its photogenic features at your own pace before you continue your journey.

At the end of the day, you will drive to Trikala, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Trikala's most popular restaurants, and connect with friendly locals for a true cultural experience.

Savor the flavors at ALVEO, a top pick for dinner tonight. Alternatively, Trikala Fortress beckons with its unique menu offerings. Also, consider Palia Istoria. With its consistent customer satisfaction, it’s an excellent option for dining in Trikala tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Soyita Art Cafe, a well-loved spot among locals and tourists. Or, head to Factory Café. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at The Love Shake, another top-rated place in the area.

Say good night to Trikala and look forward to another great day of your road trip in Greece!

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Day6

Day 6

  • Trikala
  • Kastraki
  • Thessaloniki
  • More

Drive 257 km, 4 hours 16 min

  • Trikala City Center Square
  • Matsopoulos Park
  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Meteora
  • More

Your itinerary for day 6 of your road trip in Greece includes 2 stops and features some of the highlights of Trikala and Kastraki. At the end of the day, enjoy the comforts of a top-rated hotel in Thessaloniki, where you'll spend 1 night.

Trikala City Center Square is an ideal stop early in the day. This underrated public square is a must-visit in the city. When you’re ready for your next discovery, continue to Matsopoulos Park, which may be one of the most gorgeous places you will experience today.

Fasten your seatbelt and make your way to your next stop — Kastraki, home to many well-known sights in the region. Keep in mind that your travel time from Trikala to Kastraki may take around 37 min without traffic disruptions. Upon arrival in Kastraki, we highly recommend checking out some of the top attractions.

When you're ready for some sights, head to Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, a worthwhile monastery in Kastraki. Explore its UNESCO world heritage-designated features at your own pace before you continue your journey to your next attraction, Meteora. This locally renowned monastery is a top recommendation in the area.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Treat yourself to a wonderful meal at Enoches Bar, a top-rated dining spot in Thessaloniki. If you're in the mood for something new, try O Loytros, another premier location with a delectable menu. You might also want to book a table at rOOTS. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Thessaloniki.

Explore the vibrant nightlife at Peiratis Cafe-bar after your meal, a hub for lively evenings and memorable moments. Or, head to In Rock Cafe Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Tribeca is perfect for those looking to extend their night with a touch of local flavor.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day7

Day 7

  • Thessaloniki - Departure day
  • More
  • Agias Sofias Square
  • More

Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Agias Sofias Square, a symbolic public square before you head out.

For a last-minute shopping spree in Thessaloniki, Tsimiski Street is nearby. Enjoy a variety of retail stores, dining options, and essential services in one convenient location. Browse through boutiques to find unique and stylish fashion pieces to take home.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

If you're in the mood to try something new, consider Agora Ouzeri, another top spot with a mouthwatering menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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