7-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture traveling west to Litochoro, Ioannina, and Thessaloniki

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Photo of Ammolofoi beach near Kavala, Greece, Europe. Nice sand and clear water.
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7-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture traveling west to Litochoro, Ioannina, and Thessaloniki
7-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture traveling west to Litochoro, Ioannina, and Thessaloniki
7-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture traveling west to Litochoro, Ioannina, and Thessaloniki
7-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture traveling west to Litochoro, Ioannina, and Thessaloniki
7-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture traveling west to Litochoro, Ioannina, and Thessaloniki
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Explore the best of Greece on a remarkable 7-day road trip! Combine exploration with relaxation on a self-drive tour featuring Kavala Prefecture, Krinides, Lydia, Kipia, Litochoro, Trikala, Kastraki, Ioannina, Perama, Kastanéa, Vergina, Thessaloniki, and Edessa.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Kavala Prefecture, 1 night in Litochoro, 1 night in Ioannina, and 2 nights in Thessaloniki. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Kavala Prefecture, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Kavala Prefecture, Krinides, Lydia, Kipia, Litochoro, Trikala, Kastraki, Ioannina, Perama, Kastanéa, Vergina, Thessaloniki, and Edessa, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Kavala - Arrival day
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  • Kavala Fort
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Welcome to Kavala Prefecture, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 1 night discovering what to see in Kavala Prefecture before embarking on the next leg of your journey.

Kavala Prefecture is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Kavala Fortress. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Kavala Prefecture. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Kavala Prefecture, it's often a good idea to reserve a table in advance.

Dine in style at Meltemi, a top recommendation for dinner tonight. Or, for a change of pace, Tsalapeteinos (Tsalapeteinos Urban Farm) boasts a menu that's sure to impress. Also, be sure to check out Marine Cafe Bar Restaurant. Known as a local hotspot, it’s a great choice for tonight in Kavala Prefecture.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Sofita, a well-loved spot among locals and tourists. Or, head to Beyond Cafe-bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Brickwall Pub, another top-rated place in the area.

Raise a toast to the start of your 7-day road trip in Greece!

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Day2

Day 2

  • Kavala
  • Krinides
  • Lydia
  • Kipia
  • Litochoro
  • More

Drive 277 km, 3 hours 20 min

  • Ancient theatre of Philippi
  • Holy Baptistery of Saint Lydia of Philippi
  • Wax Museum in Kipia
  • More

Experience an unparalleled adventure on day 2 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Krinides, Lydia, and Kipia. At the end of the day, you will retreat to the hotel of your choice in Litochoro, where will spend 1 night.

As you explore Krinides’s charming streets, take in the lively atmosphere and get to know the character of the town.

Krinides’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Kavala Prefecture behind. This drive usually takes around 24 min. Krinides welcomes you with a multitude of unique vacation experiences.

Our first attraction recommendation in Krinides is Ancient Theatre Of Philippi, an intriguing archeological site that draws attention for its picture-perfect features.

Continue your road trip and head to your next destination, Lydia. This car ride takes around 4 min.

When you're ready for some sights, head to Holy Baptistery Of Saint Lydia Of Philippi, a frequently visited church in Lydia. Explore its picture-perfect features at your own pace before you continue your journey.

Embrace the thrill of the open road as you wave goodbye to Lydia and set your GPS to Kipia. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 30 min. Upon reaching Kipia, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Wax Museum In Kipia. Spend some time admiring the detailed features of the wax museum before you continue to your next stop.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Litochoro. Litochoro offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Litochoro. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Ntisko Romeiko, a highly recommended choice for tonight's dinner.

Celebrate another amazing day of your road trip adventure in Greece!

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Day3

Day 3

  • Litochoro
  • Trikala
  • Kastraki
  • Ioannina
  • More

Drive 262 km, 4 hours 7 min

  • Trikala City Center Square
  • Central Bridge
  • Matsopoulos Park
  • Meteora
  • More

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, including Trikala and Kastraki. When you’re not sightseeing, take time to relax at your chosen hotel in Ioannina, where you’ll be staying for 1 night.

Embrace the thrill of the open road as you wave goodbye to Litochoro and set your GPS to Trikala. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 41 min. Upon reaching Trikala, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Trikala City Center Square. Spend some time admiring the visually striking features of the public square before you continue to your next stop. Then, head to Central Bridge. This up-and-coming public square is a traveler-favorite in the city.

If you're keen to see more, continue to Matsopoulos Park. Feed your curiosity by learning something new about the park.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Kastraki. This drive usually takes around 33 min, without any stops or traffic disruptions.

Set out on a self-guided sightseeing tour at Meteora and explore the UNESCO world heritage-listed features.

At the end of the day, you will drive to Ioannina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at To Dodeka Cafe Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Mustagogia? It's another excellent option with a diverse menu. Consider reserving a table at Accademia Del Panino as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Ioannina.

Unwind after your meal by stepping into ⚜ V E D E M A ⚜. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Hogwarts Tales And Spirits offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Chevalier, another top-rated bar in the area.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Greece.

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Day4

Day 4

  • Ioannina
  • Perama
  • Kastanéa
  • Thessaloniki
  • More

Drive 282 km, 3 hours 51 min

  • Ioannina Castle
  • Cave of Perama
  • Holy Monastery of the Virgin Mary Soumela
  • More

On day 4 of your road trip in Greece, your travel plans include 4 stops at the most scenic, wondrous, and interesting places in the region. Ioannina, Perama, Kastanéa, and Vergina are on today's agenda. In the evening, you’ll end up in Thessaloniki, where you will stay for 2 nights.

Awaiting your discovery is the locally renowned Ioannina Castle, a visually striking castle in Ioannina.

Perama’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Ioannina behind. This drive usually takes around 9 min. Perama welcomes you with a multitude of unique vacation experiences.

For a more meaningful self-guided tour of the city's best attractions, visit Cave Of Perama, a beloved cave that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re ready to jump back into the car and say goodbye to Perama, you’ll hit the road in the direction of Kastanéa. This drive usually takes around 2 hours 7 min.

When you're ready for some sights, head to Holy Shrine Of The Virgin Mary Soumela, a curiosity-inducing church in Kastanéa. Explore its breathtaking features at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and relax before you head out to tour the city.

Thessaloniki is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Thessaloniki.

Enjoy a delicious meal at Kitchen Bar, a highly-rated dining destination in Thessaloniki. If you're eager to try something different, consider The Greek, another top spot with a tantalizing menu. You might also want to secure a reservation at Phanós. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Thessaloniki this evening.

After savoring a delicious meal, step into the vibrant nightlife at Beetle Bar, where the evening is just getting started. In the same way, Vogatsikou 3 offers a unique charm perfect for experiencing the local bar scene in Thessaloniki. Souel is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day5

Day 5

  • Thessaloniki
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Drive 6 km, 22 min

  • Aristotelous Square
  • White Tower of Thessaloniki
  • The Umbrellas by Zongolopoulos
  • Archaeological Museum of Thessaloniki
  • Arch of Galerius
  • More

Day 5 offers an itinerary packed with the best things to see in Kavala Prefecture. You’ll stay in Thessaloniki for 1 night more, offering you enough time to explore at a relaxed pace.

Aristotelous Square makes a great addition to your morning plans. This well-known public square is a romantic place to see in Thessaloniki. Continue your discovery at White Tower Of Thessaloniki, a breathtaking monument with stories to tell.

As you stroll around Thessaloniki, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to The Umbrellas Sculpture By Zogolopoulos. This notable art installation offers a noteworthy encounter with Thessaloniki. Next, make your way to Archaeological Museum Of Thessaloniki to add another highlight to your day. After that, visit Arch Of Galerius And Rotunda, a well-known monument that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Thessaloniki.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

Thessaloniki is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Thessaloniki.

Dine in style at Mamalouka, a top recommendation for dinner tonight. Or, for a change of pace, Clochard boasts a menu that's sure to impress. Also, be sure to check out Sofi's House Restaurant. Known as a local hotspot, it’s a great choice for tonight in Thessaloniki.

Continue the enjoyment post-dinner at Castra- All Day Terrace Bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Barbaben - Bar/ba/ben offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Apallou. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Head back to your accommodation in Thessaloniki and get some rest to prepare for another magical day of your road trip in Greece.

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Day6

Day 6

  • Thessaloniki
  • Edessa
  • Kavala
  • More

Drive 326 km, 4 hours 35 min

  • Kapani
  • Agias Sofias Square
  • Edessa Waterfalls
  • Lazaristes Monastery
  • More

Dive into day 6 of your remarkable road trip in Greece. Today you'll explore 2 destinations, including Thessaloniki and Edessa. At the end of the day, you’ll unwind at one of the finest accommodations in Kavala Prefecture, where you'll spend 1 night.

To truly experience Thessaloniki, make sure to drop by Kapani. This well-known market is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Agias Sofias Square, one of the city’s best highlights.

Embrace the thrill of the open road as you wave goodbye to Thessaloniki and set your GPS to Edessa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 22 min. Upon reaching Edessa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Waterfalls Park, Edessa, a locally renowned waterfall that everyone visiting Edessa should see.

Savor the day by heading to Lazaristes Monastery, an often recommended monastery that draws visitors from near and far.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Kavala Prefecture. Kavala Prefecture offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Kavala Prefecture's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at FRANCO'S, an iconic dining spot in Kavala Prefecture. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Psaraki, a popular restaurant in Kavala Prefecture. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Proto Katsiki, a hidden gem nestled in Kavala Prefecture. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the excitement of the evening going by visiting a bar or two. Blue is an excellent place to start. You could also check out Meta Tis Deka, offering a different kind of charm. A last recommendation for the day is Ypobrýchio. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Savor another day of unforgettable experiences in Greece!

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Day7

Day 7

  • Kavala - Departure day
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  • Faliro Park
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Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Kavala Prefecture before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Faliro Park before you head out.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Kavala Prefecture.

Have a fantastic dining experience at “Paraliakon” Estiatorio, a highly recommended choice for tonight's dinner. If you're looking to mix things up, 180° sun & lounge offers an enticing alternative with its varied menu.

You’ll then say farewell to Kavala Prefecture. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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