6-Day Greece Self-Drive Road Trip With Itinerary from Preveza to Ioannina and Patras and surrounding area

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Photo of Parga the Greek Caribbean in Preveza, famous Traditional tropical destination vacation summer tourist attraction with the deep blue ocean of Ionian sea Greece.
Photo of aerial panoramic view of the historical castle of Pantokrator. Its one of the 3 castles in Preveza city located at the south end of the old city, near the beach of Kyani Akti.
6-Day Greece Self-Drive Road Trip With Itinerary from Preveza to Ioannina and Patras and surrounding area
6-Day Greece Self-Drive Road Trip With Itinerary from Preveza to Ioannina and Patras and surrounding area
6-Day Greece Self-Drive Road Trip With Itinerary from Preveza to Ioannina and Patras and surrounding area
6-Day Greece Self-Drive Road Trip With Itinerary from Preveza to Ioannina and Patras and surrounding area
6-Day Greece Self-Drive Road Trip With Itinerary from Preveza to Ioannina and Patras and surrounding area
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Experience the freedom of the open road on an unforgettable 6-day road trip in Greece! Embark on a self-drive tour that caters to every traveler, featuring destinations like Pantokratoras, Preveza, Mesopotamo, Kanallaki, Glyki, Kamarina, Ioannina, Perama, Neo Bizani, Patras, Kastria, Zachlorou, Antirio, Nafpaktos, Mesolongi, and Agrinio.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Preveza, 1 night in Ioannina, and 2 nights in Patras. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Preveza, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Αcheron Springs and Ioannina Castle are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Pantokratoras, Preveza, Mesopotamo, Kanallaki, Glyki, Kamarina, Ioannina, Perama, Neo Bizani, Patras, Kastria, Zachlorou, Antirio, Nafpaktos, Mesolongi, and Agrinio, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Preveza - Arrival day
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  • Pantokratoras promenade
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Your road trip adventure in Greece begins as soon as you reach Preveza and pick up your car. You’ll stay here for 1 night and explore what to see in Preveza, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Preveza is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Pantokratoras Promenade. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Preveza. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Preveza, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Ano Vlanto (Ano Vlanto), an excellent option for tonight's dining. Looking for something different? Ventura Tavern offers a tantalizing alternative with its diverse menu. And don’t miss Monolithi Beach Bar. Known for great service, it’s a fantastic choice for tonight in Preveza.

Continue your evening by exploring the vibrant nightlife scene at Roloi, a prime destination for a thrilling night out. Also, don’t forget to check out Markus Espresso & Wine Bar, a bar that offers unique local touches. Likewise, Metropolis Cafe (mitropolis Kafe) provides an excellent alternative for a fun evening.

Raise a toast to the start of your 6-day road trip in Greece!

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Day2

Day 2

  • Preveza
  • Mesopotamo
  • Kanallaki
  • Glyki
  • Ioannina
  • More

Drive 209 km, 3 hours 32 min

  • Necromanteion of Acheron
  • Αcheron Springs
  • Acheron Springs - Canyon Acheron
  • More

On day 2 of your road trip in Greece, your travel plans include 4 stops at the most scenic, wondrous, and interesting places in the region. Mesopotamo, Kanallaki, Glyki, and Kamarina are on today's agenda. In the evening, you’ll end up in Ioannina, where you will stay for 1 night.

As you explore Mesopotamo’s charming streets, take in the lively atmosphere and get to know the character of the village.

Mesopotamo’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Preveza behind. This drive usually takes around 36 min. Mesopotamo welcomes you with a multitude of unique vacation experiences.

Necromanteion Of Acheron is a curiosity-inducing archeological site we recommend visiting today. Discover its photogenic features before continuing your self-guided tour.

When you’re ready to jump back into the car and say goodbye to Mesopotamo, you’ll hit the road in the direction of Kanallaki. This drive usually takes around 22 min.

When you're ready for some sights, head to Αcheron Springs, a notable hiking area in Kanallaki. Explore its eye-catching features at your own pace before you continue your journey.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Glyki may take around 8 min. Upon your arrival in Glyki, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Savor the day by heading to Acheron Springs - Canyon Acheron, a beloved canyon that draws visitors from near and far.

At the end of the day, you will drive to Ioannina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at To Dodeka Cafe Bar, a top-rated dining spot in Ioannina. If you're in the mood for something new, try Mustagogia, another premier location with a delectable menu. You might also want to book a table at Accademia Del Panino. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Ioannina.

To truly maximize your evening out, consider visiting ⚜ V E D E M A ⚜ after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Hogwarts Tales And Spirits, another bar with an inviting ambiance. Similarly, Chevalier also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Head back to your accommodation in Ioannina and get some rest to prepare for another magical day of your road trip in Greece.

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Day3

Day 3

  • Ioannina
  • Perama
  • Neo Bizani
  • Patras
  • More

Drive 235 km, 3 hours 18 min

  • The Clock Tower of Ioannina
  • Ioannina Castle
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • Vrellis Greek History Museum (Wax Museum)
  • More

Your itinerary for day 3 of your road trip in Greece includes 3 stops and features some of the highlights of Ioannina, Perama, and Neo Bizani. At the end of the day, enjoy the comforts of a top-rated hotel in Patras, where you'll spend 2 nights.

The Clock Tower Of Ioannina makes a great addition to your morning plans. This beloved monument is a picture-perfect place to see in Ioannina. Continue your discovery at Ioannina Castle, a culturally significant castle with stories to tell.

As you stroll around Ioannina, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Ic Kale Acropolis Of Ioannina. This intriguing archeological site offers a picture-perfect encounter with Ioannina. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Ioannina.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Perama may take around 11 min. Upon your arrival in Perama, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Cave Of Perama, a curiosity-inducing cave that everyone visiting Perama should see.

Neo Bizani’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Perama behind. This drive usually takes around 30 min. Neo Bizani welcomes you with a multitude of unique vacation experiences.

Our first attraction recommendation in Neo Bizani is Moyseio Ellinikis Istorias Payloy Vrelli, an up-and-coming museum that draws attention for its noteworthy features.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Patras. Patras offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Patras. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Tag, an iconic dining spot in Patras. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bianco, a popular restaurant in Patras. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Carousello, a hidden gem nestled in Patras. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After savoring a delicious meal, step into the vibrant nightlife at Sofita, where the evening is just getting started. In the same way, Charama Therino offers a unique charm perfect for experiencing the local bar scene in Patras. Notos is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day4

Day 4

  • Patras
  • Kastria
  • Zachlorou
  • More

Drive 213 km, 3 hours 54 min

  • Cave Lakes - Kastria Cave
  • Mega Spileon Monastery
  • Church of Agios Andreas
  • Patras' South Park - Notio Parko Patras
  • More

On day 4 of your road trip in Greece, you’ll start and end your day in Patras, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Patras, there’s no need to rush. Experience Kastria, Zachlorou, and Patras to the fullest today with this curated day itinerary.

No visit to Patras is complete without Holy Church Of Saint Andrew. This often recommended church is one of the top attractions in the village. Proceed to Patras' South Park - Notio Parko Patras, another must-visit attraction.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Kastria. This drive usually takes around 1 hour 44 min, without any stops or traffic disruptions.

When you're ready for some sights, head to Cave Lakes - Kastria Cave, a worthwhile cave in Kastria. Explore its majestic features at your own pace before you continue your journey.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Zachlorou. This drive usually takes around 35 min, without any stops or traffic disruptions.

When you're ready for some sights, head to Mega Spileon Monastery, a worthwhile monastery in Zachlorou. Explore its instagrammable features at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll return to Patras and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Patras. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Fork, an iconic dining spot in Patras. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Flouskounis food, a popular restaurant in Patras. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Big Ben, a hidden gem nestled in Patras. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Explore the vibrant nightlife at Minimal after your meal, a hub for lively evenings and memorable moments. Or, head to Beer Bar Q for a great selection of flavorful drinks and a charming setting. Furthermore, Distinto Mall is perfect for those looking to extend their night with a touch of local flavor.

Say good night to Patras and look forward to another great day of your road trip in Greece!

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Day5

Day 5

  • Patras
  • Antirio
  • Naypaktos
  • Mesolongi
  • Preveza
  • More

Drive 188 km, 3 hours 10 min

  • Rion-Antirion Bridge
  • Psani
  • History and Art Museum of Messolonghi
  • Garden of Heroes
  • More

On day 5 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 4 destinations, including Antirio, Nafpaktos, Mesolongi, and Agrinio. When you’re not sightseeing, take time to relax at your chosen hotel in Preveza, where you’ll be staying for 1 night.

Embrace the thrill of the open road as you wave goodbye to Patras and set your GPS to Antirio. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 15 min. Upon reaching Antirio, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Set out on a self-guided sightseeing tour at Charilaos Trikoupis Rio - Antirrio Bridge and explore the eye-catching features.

Nafpaktos’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Antirio behind. This drive usually takes around 10 min. Nafpaktos welcomes you with a multitude of unique vacation experiences.

Our first attraction recommendation in Nafpaktos is Psani, a locally appreciated beach that draws attention for its romantic features.

Embrace the thrill of the open road as you wave goodbye to Nafpaktos and set your GPS to Mesolongi. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 38 min. Upon reaching Mesolongi, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to History And Art Museum Of Messolonghi, an intriguing museum that everyone visiting Mesolongi should see. Next, head to Garden Of Heroes. This culturally significant cemetery is one of the most increasingly popular attractions in the region.

When you’re done exploring for the day, you’ll drive to your hotel in Preveza. Check in and relax before you head out to tour the city.

Preveza is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Preveza.

Enjoy a delicious meal at Treli Garida, a highly-rated dining destination in Preveza. If you're eager to try something different, consider Alati Seafood & More, another top spot with a tantalizing menu. You might also want to secure a reservation at Saitan Bazaar - Saitan Pazar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Preveza this evening.

If you’re not ready to end the night just yet, Hipster Cafe offers a perfect venue to relax and savor a drink. Similarly, Adesso is well-suited for those looking to unwind in a social setting. Art Cafe "botilia Sto Pelago" is another excellent spot to enjoy a nightcap after a delightful meal.

Relax and look forward to more memorable moments to come!

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Day6

Day 6

  • Preveza - Departure day
  • More

Day 6 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Preveza before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

For a shopping spree in Preveza, we recommend the lively Preveza Marina. Here, you'll find a range of shops you can browse for some souvenir shopping. Discover boutiques with stylish fashion choices to upgrade your wardrobe.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Preveza.

Treat yourself to a delightful dinner at Symposio, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Prevere Cafe bar? It's another excellent option with a diverse menu.

You’ll then say farewell to Preveza. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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