5-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Preveza and Patras

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Photo of Plakidas Bridge in Ioannina in Greece by DanaTentis
Photo of Ioannina lake Pamvotida in Epirus Region, Greece.
5-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Preveza and Patras
5-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Preveza and Patras
5-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Preveza and Patras
5-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Preveza and Patras
5-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Preveza and Patras
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Explore the best of Greece on a remarkable 5-day road trip! Combine exploration with relaxation on a self-drive tour featuring Ioannina, Perama, Neo Bizani, Preveza, Agios Nikitas, Fryni, Patras, Antirio, and Mesolongi.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Ioannina, 1 night in Preveza, and 1 night in Patras. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Ioannina, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Kathisma 1 and Ioannina Castle are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Ioannina, Perama, Neo Bizani, Preveza, Agios Nikitas, Fryni, Patras, Antirio, and Mesolongi, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Ioannina - Arrival day
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  • Ioannina Castle
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Your road trip adventure in Greece begins as soon as you reach Ioannina and pick up your car. You’ll stay here for 1 night and explore what to see in Ioannina, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Ioannina is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ioannina Castle. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Ioannina. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at To Dodeka Cafe Bar, an iconic dining spot in Ioannina. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mustagogia, a popular restaurant in Ioannina. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Accademia Del Panino, a hidden gem nestled in Ioannina. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at ⚜ V E D E M A ⚜, a well-loved spot among locals and tourists. Or, head to Hogwarts Tales And Spirits. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Chevalier, another top-rated place in the area.

Raise a toast to the start of your 5-day road trip in Greece!

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Day2

Day 2

  • Ioannina
  • Perama
  • Neo Bizani
  • Preveza
  • More

Drive 111 km, 2 hours 5 min

  • Cave of Perama
  • Museum "Arslan Pasha"
  • Ich Kale Acropolis of Ioannina
  • Silversmithing Museum
  • Vrellis Greek History Museum (Wax Museum)
  • More

Dive into day 2 of your remarkable road trip in Greece. Today you'll explore 3 destinations, including Perama, Ioannina, and Neo Bizani. At the end of the day, you’ll unwind at one of the finest accommodations in Preveza, where you'll spend 1 night.

Catch Museum "arslan Pasha" before the crowds roll in. Next, dive into the picture-perfect features of Ic Kale Acropolis Of Ioannina, a must-visit archeological site in the town.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Silversmithing Museum Of Ioannina, an underrated museum.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Perama.

Our first attraction recommendation in Perama is Cave Of Perama, an often recommended cave that draws attention for its visually striking features.

Continue your road trip and head to your next destination, Neo Bizani. This car ride takes around 22 min.

For a more meaningful self-guided tour of the town's best attractions, visit Moyseio Ellinikis Istorias Payloy Vrelli, an increasingly popular museum that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Preveza. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Preveza, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Ano Vlanto (Ano Vlanto), a highly recommended choice for tonight's dinner. If you're looking to mix things up, Ventura Tavern offers an enticing alternative with its varied menu. Additionally, Monolithi Beach Bar is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Preveza.

Keep the excitement of the evening going by visiting a bar or two. Roloi is an excellent place to start. You could also check out Markus Espresso & Wine Bar, offering a different kind of charm. A last recommendation for the day is Metropolis Cafe (mitropolis Kafe). This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Head back to your accommodation in Preveza and get some rest to prepare for another magical day of your road trip in Greece.

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Day3

Day 3

  • Preveza
  • Agios Nikitas
  • Fryni
  • Patras
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Drive 216 km, 3 hours 32 min

  • Kathisma 1
  • Faneromeni Monastery
  • Patras' South Park - Notio Parko Patras
  • Church of Agios Andreas
  • More

Your itinerary for day 3 of your road trip in Greece includes 3 stops and features some of the highlights of Agios Nikitas, Fryni, and Patras. At the end of the day, enjoy the comforts of a top-rated hotel in Patras, where you'll spend 1 night.

When you’re ready to jump back into the car and say goodbye to Preveza, you’ll hit the road in the direction of Agios Nikitas. This drive usually takes around 58 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Kathisma 1, a locally renowned beach that everyone visiting Agios Nikitas should see.

When you’ve had your share of Agios Nikitas, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Fryni. Your travel time is around 18 min.

When you're ready for some sights, head to Faneromeni Monastery, an intriguing monastery in Fryni. Explore its inviting features at your own pace before you continue your journey.

After soaking in Fryni’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Patras. Expect your car journey to take a minimum of 1 hour 59 min. When you arrive in Patras, it's time to take a break from the road.

One of our top recommendations for your sightseeing is Patras' South Park - Notio Parko Patras. Spend some time admiring the visually striking features of the park before you continue to your next stop. Then, head to Holy Church Of Saint Andrew. This locally appreciated church is a traveler-favorite in the village.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Patras. Patras offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Patras is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Patras.

Enjoy a delicious meal at Tag, a top-rated dining destination in Patras. If you're in the mood to try something new, consider Bianco, another top spot with a mouthwatering menu. You might also want to secure a reservation at Carousello. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Patras this evening.

Round off your dining experience by visiting Sofita, a prime location for a drink. Alternatively, explore the distinctive characteristics of Charama Therino, a bar catering to every mood and preference. Notos likewise offers a unique atmosphere, perfect for a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day4

Day 4

  • Patras
  • Antirio
  • Mesolongi
  • Ioannina
  • More

Drive 220 km, 2 hours 53 min

  • King George Ι Square (Patras)
  • St Nicholas Stairway
  • Patras Castle
  • Rion-Antirion Bridge
  • Garden of Heroes
  • More

On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, including Patras, Antirio, and Mesolongi. When you’re not sightseeing, take time to relax at your chosen hotel in Ioannina, where you’ll be staying for 1 night.

King George I Square (patras) makes a great addition to your morning plans. This intriguing public square is a romantic place to see in Patras. Continue your discovery at St. Nicholas Stairway, a romantic street with stories to tell.

As you stroll around Patras, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Patras Castle. This beloved castle offers a culturally significant encounter with Patras. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Patras.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Antirio may take around 15 min. Upon your arrival in Antirio, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Set out on a self-guided sightseeing tour at Charilaos Trikoupis Rio - Antirrio Bridge and explore the symbolic features.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Mesolongi. This drive usually takes around 25 min, without any stops or traffic disruptions.

Our first attraction recommendation in Mesolongi is Garden Of Heroes, a beloved cemetery that draws attention for its masterful features.

At the end of the day, you will drive to Ioannina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Ioannina. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delicious dinner at Spitaki me thea, an excellent option for tonight's dining. Looking for something different? Frontzoy Politeia - Frontzu Politia Restaurant offers a tantalizing alternative with its diverse menu. And don’t miss Papi Cafe Bistro. Known for great service, it’s a fantastic choice for tonight in Ioannina.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Scala, a well-loved spot among locals and tourists. Or, head to Route 66 Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Palia Agora, another top-rated place in the area.

Raise your glass to another unforgettable day in Greece!

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Day5

Day 5

  • Ioannina - Departure day
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  • The Clock Tower of Ioannina
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Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Ioannina before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at The Clock Tower Of Ioannina. This frequently visited monument is a hotspot among locals.

Make the most of your final day in Greece by visiting Ioannina’s iconic markets and shopping establishments in the buzzing Epirus Street. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation. You can also browse through boutiques for stylish fashion choices. Savor your final moments in Greece at a cozy cafe while relaxing with a cup of coffee or tea.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Ioannina.

If you're in the mood to try something new, consider Frontzu Politia - Hotel, another top spot with a mouthwatering menu.

You’ll then say farewell to Ioannina. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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