6-Day France Self-Drive Road Trip With Itinerary from Lyon to Avignon and Marseille

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Photo of Lyon cityscape from Saone river with colorful houses and river, France.
Photo of summer view over Vieux Lyon, with famous cathedral Fourviere, and Croix Rousse in Lyon, France.
6-Day France Self-Drive Road Trip With Itinerary from Lyon to Avignon and Marseille
6-Day France Self-Drive Road Trip With Itinerary from Lyon to Avignon and Marseille
6-Day France Self-Drive Road Trip With Itinerary from Lyon to Avignon and Marseille
6-Day France Self-Drive Road Trip With Itinerary from Lyon to Avignon and Marseille
6-Day France Self-Drive Road Trip With Itinerary from Lyon to Avignon and Marseille
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Experience the freedom of the open road on an unforgettable 6-day road trip in France! Embark on a self-drive tour that caters to every traveler, featuring destinations like Lyon, Caluire-et-Cuire, Avignon, Marseille, and Cassis.

This perfectly planned road trip itinerary takes you through some of the best places to see in France. You will spend 3 nights in Lyon, 1 night in Avignon, and 1 night in Marseille. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in France. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Lyon, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover France on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in France. Parc De La Tête D'or and Notre-dame De La Garde (marseille) are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Lyon, Caluire-et-Cuire, Avignon, Marseille, and Cassis, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of France. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in France.

Throughout your road trip in France, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in France.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in France fill up quickly, so book your spot early. Select a date and start planning your road trip in France today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Lyon - Arrival day
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  • Place Bellecour
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Your road trip adventure in France begins as soon as you reach Lyon and pick up your car. You’ll stay here for 2 nights and explore what to see in Lyon, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Lyon is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Place Bellecour. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Lyon. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Lyon, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Nuage café, an iconic dining spot in Lyon. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Café du Rhône, a popular restaurant in Lyon. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Agastache Restaurant, a hidden gem nestled in Lyon. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your delicious meal, get a taste of the vibrant nightlife with a visit to L' Antiquaire, known for its inviting atmosphere. Black Forest Society is another great option if you’re looking for a place to get the night started. Similarly, Pompette provides a great setting to enjoy the night away.

Raise a toast to the start of your 6-day road trip in France!

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Day2

Day 2

  • Lyon
  • Caluire-et-Cuire
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Drive 17 km, 1 hour 12 min

  • parc de la Tête d'Or
  • Gallo-Roman Museum of Lyon-Fourvière
  • La Basilique Notre Dame de Fourvière
  • Lyon Cathedral
  • La Croix-Rousse
  • Vieux Lyon
  • More

Greet day 2 of your road trip in France with a smile and start your day with a hearty breakfast. You have 1 night to stay in Lyon, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Caluire-et-Cuire and Lyon.

La Croix-Rousse is a fantastic place you can explore today in Caluire-et-Cuire. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Caluire-et-Cuire-way-of-life and visit all the nearby sights. You should also check out Vieux Lyon, a neighborhood offering more opportunities to enjoy the city’s vibrant atmosphere and landmarks.

Your adventure in Lyon is only getting started when you visit Gallo-roman Museum Of Lyon-fourvière, a locally appreciated local hot spot. Another notable attraction to explore is Basilica Of Notre-dame De Fourvière. This interesting church is known for its breathtaking appeal.

After soaking in the highlights of these sights, take some time to wander Lyon's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Lyon Cathedral. This enchanting church offers a fascinating experience that many visitors find memorable.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Caluire-et-Cuire.

Our first attraction recommendation in Caluire-et-Cuire is Parc De La Tête D'or, an astonishing park that draws attention for its eye-catching features.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lyon.

After a day of adventure, treat yourself to an exquisite dinner at one of Lyon's best restaurants.

Savor the flavors at Bulle - Restaurant de Fourvière - Guy Lassausaie, a top pick for dinner tonight. Alternatively, Bernachon Chocolats beckons with its unique menu offerings. Also, consider La Mère Léa. With its consistent customer satisfaction, it’s an excellent option for dining in Lyon tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, The James Joyce Pub stands out as an excellent choice for a post-dinner cocktail. Alternatively, Broc'bar offers an ideal atmosphere to enjoy the pleasures of the night. La Passagère is also a great option that provides a perfect setting for a relaxing evening.

Savor another day of unforgettable experiences in France!

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Day3

Day 3

  • Lyon
  • Avignon
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Drive 228 km, 2 hours 52 min

  • Remparts d'Avignon
  • Palais des Papes
  • Jardin des doms
  • Musée du Petit Palais
  • More

Your itinerary for day 3 of your road trip in France includes 1 stop and features some of the highlights of Avignon. At the end of the day, enjoy the comforts of a top-rated hotel in Avignon, where you'll spend 1 night.

Embrace the thrill of the open road as you wave goodbye to Lyon and set your GPS to Avignon. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 22 min. Upon reaching Avignon, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

For a more meaningful self-guided tour of the city's best attractions, visit Remparts D'avignon, a frequently visited historical landmark that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Palais Des Papes and admire its picture-perfect features.

When you’re ready, continue to Jardin Des Doms, an intriguing park beloved by locals and tourists alike. Don't miss out on Musée Du Petit Palais, another highlight of the area that promises a memorable visit.

When you’re done exploring for the day, you’ll drive to your hotel in Avignon. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Avignon. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Restaurant Pollen, a top recommendation for dinner tonight. Or, for a change of pace, Chez Bodus Le Garçon Boucher boasts a menu that's sure to impress. Also, be sure to check out La Cuisine de Papa. Known as a local hotspot, it’s a great choice for tonight in Avignon.

Extend your evening after a delightful meal by visiting Le 17 Place Aux Vins Avignon • Bar À Vin / Caviste, which offers the perfect atmosphere for a night out. Moreover, Barberousse Avignon is another popular option for a drink or two. Likewise, The Red Sky also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass to another unforgettable day in France!

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Day4

Day 4

  • Avignon
  • Marseille
  • More

Drive 132 km, 2 hours 31 min

  • Calanques National Park
  • Basilica of Notre-Dame of la Garde
  • Mucem - Museum of Civilizations of Europe and the Mediterranean
  • More

On day 4 of your road trip in France, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Marseille are on today's agenda. In the evening, you’ll end up in Marseille, where you will stay for 1 night.

After soaking in Avignon’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Marseille. Expect your car journey to take a minimum of 1 hour 32 min. When you arrive in Marseille, it's time to take a break from the road.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Calanques National Park, a locally renowned national park that everyone visiting Marseille should see. Next, head to Notre-dame De La Garde (marseille). This visually striking church is one of the most locally renowned attractions in the region.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Marseille. Marseille offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Marseille is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Marseille.

Treat yourself to a wonderful meal at Chez Roger, a top-rated dining spot in Marseille. If you're in the mood for something new, try Les Mets des Saintes, another premier location with a delectable menu. You might also want to book a table at Hôtel Maison Montgrand Vieux-Port. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Marseille.

Explore the vibrant nightlife at Le Traquenard after your meal, a hub for lively evenings and memorable moments. Or, head to La Dame Du Mont for a great selection of flavorful drinks and a charming setting. Furthermore, Polikarpov is perfect for those looking to extend their night with a touch of local flavor.

Relax and recharge in preparation for another adventurous day in France!

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Day5

Day 5

  • Marseille
  • Cassis
  • Lyon
  • More

Drive 387 km, 4 hours 41 min

  • Old Port of Marseille
  • St Vincent de Paul Church
  • Calanque de Port-Miou
  • Route des crêtes
  • More

Dive into day 5 of your remarkable road trip in France. Today you'll explore 2 destinations, including Marseille and Cassis. At the end of the day, you’ll unwind at one of the finest accommodations in Lyon, where you'll spend 1 night.

Make a stop at Old Port Of Marseille. This often recommended marina is a must-visit for travelers looking for a unique holiday experience. Make your way to St. Vincent De Paul Church located in Marseille for another exciting encounter.

Set your GPS to Cassis and hit the road. Expect a journey of approximately 43 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Cassis beckons with new experiences!

When you're ready for some sights, head to Calanque De Port-miou, a frequently visited marina in Cassis. Explore its serene features at your own pace before you continue your journey to your next attraction, Route Des Crêtes. This locally appreciated point of interest is a top recommendation in the area.

At the end of the day, you will drive to Lyon, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lyon. Enjoy a relaxing evening as you savor delicious local cuisine.

Don’t miss out on dining at Nosch, a top-rated dining destination in Lyon. If you're in the mood to try something new, consider Auberge des canuts - Bouchon Lyonnais, another top spot with a mouthwatering menu. You might also want to secure a reservation at Vieille Canaille. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lyon this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to La Raffinerie, known for its inviting atmosphere. Bar Le Florian, Cocktails & Spirits is another great option if you’re looking for a place to get the night started. Similarly, Mos - Maker Of Stories provides a great setting to enjoy the night away.

Say good night to Lyon and look forward to another great day of your road trip in France!

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Day6

Day 6

  • Lyon - Departure day
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Day 6 of your road trip in France is your departure day. This is your chance to catch a last glimpse of Lyon before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

For a last-minute shopping spree in Lyon, Part-Dieu Mall is nearby. Enjoy a variety of retail stores, dining options, and essential services in one convenient location.

Before you conclude your road trip in France, drop by another restaurant for a last chance at a memorable dining experience in Lyon.

Have a fantastic dining experience at Restaurant Le Parloir, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Café Terroir offers an enticing alternative with its varied menu.

You’ll then say farewell to Lyon. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in France!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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