One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ústí Nad Labem and Špindlerův Mlýn and surrounding area

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Photo of old town pier architecture and Charles Bridge over Vltava river in Prague, Czech Republic.
Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ústí Nad Labem and Špindlerův Mlýn and surrounding area
One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ústí Nad Labem and Špindlerův Mlýn and surrounding area
One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ústí Nad Labem and Špindlerův Mlýn and surrounding area
One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ústí Nad Labem and Špindlerův Mlýn and surrounding area
One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ústí Nad Labem and Špindlerův Mlýn and surrounding area
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Experience the freedom of the open road on an unforgettable 8-day road trip in the Czech Republic! Embark on a self-drive tour that caters to every traveler, featuring destinations like Prague, Plzeň, Karlštejn, Průhonice, Kutná Hora, Ústí Nad Labem, Mezná, Děčín, Vysoká Lípa, Harrachov, Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 5 nights in Prague, 1 night in Ústí Nad Labem, and 1 night in Špindlerův Mlýn. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Prague, Plzeň, Karlštejn, Průhonice, Kutná Hora, Ústí Nad Labem, Mezná, Děčín, Vysoká Lípa, Harrachov, Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Day1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay here for 4 nights and explore what to see in Prague, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Charles Bridge. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Prague. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at U Tellerů, an excellent option for tonight's dining. Looking for something different? Restaurace U Bansethů offers a tantalizing alternative with its diverse menu. And don’t miss Eska Restaurant and Bakery. Known for great service, it’s a fantastic choice for tonight in Prague.

Continue the enjoyment post-dinner at Anonymous Shrink's Office, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Bar No. 7 - Prague offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Kontakt Bar. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise a toast to the start of your 8-day road trip in the Czech Republic!

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Day2

Day 2

  • Prague
  • More

Drive 15 km, 1 hour 5 min

  • Prague Castle
  • St. Vitus Cathedral
  • Dancing House
  • Vyšehrad
  • National Museum in Prague
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Prague. You’ll stay in Prague for 3 nights.

To truly experience Prague, make sure to drop by Prague Castle. This world-famous castle is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is St. Vitus Cathedral, one of the city’s best highlights.

Next, check out Dancing House, one of the most top-rated places to see in Prague. This art installation is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Vyšehrad. Wander around and soak in the history-steeped atmosphere this castle offers. Then, head to Národní Muzeum (national Museum, Prague), a top-rated museum that adds another dimension to your day.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

Don’t miss out on dining at Brasileiro Restaurant, a top-rated dining destination in Prague. If you're in the mood to try something new, consider Restaurant Meat Beer, another top spot with a mouthwatering menu. You might also want to secure a reservation at Restaurace Století. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

Extend your evening after a delightful meal by visiting Bowla Bar, which offers the perfect atmosphere for a night out. Moreover, The Saints is another popular option for a drink or two. Likewise, Beergeek Bar also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Head back to your accommodation in Prague and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day3

Day 3

  • Prague
  • More

Drive 27 km, 1 hour 4 min

  • Petrin Tower
  • Prague Astronomical Clock
  • Old Town Square
  • Powder Tower
  • Prague Zoo
  • More

Day 3 of your road trip across the Czech Republic promises a magnificent time exploring what to see in Prague. You have 2 nights left in Prague. Take the opportunity to experience more of the best attractions and activities in the city.

Petřín Lookout Tower is an ideal stop early in the day. This popular observation deck is a must-visit in the city. When you’re ready for your next discovery, continue to Prague Astronomical Clock, which may be one of the most history-steeped places you will experience today.

One of the best things about exploring Prague on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Old Town Square, an iconic public square in the city. If you’re up for more discoveries, don’t forget to reserve some time for Powder Tower and Prague Zoo.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at BeBop Bar, a highly-rated dining destination in Prague. If you're eager to try something different, consider Café restaurant Palanda, another top spot with a tantalizing menu. You might also want to secure a reservation at Restaurace Tiskárna. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Prague this evening.

Unwind after your meal by stepping into Uhříněveský Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Boothill Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Manesova Bar And Books, another top-rated bar in the area.

As the sun sets, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day4

Day 4

  • Prague
  • Plzeň-City District
  • Karlštejn
  • More

Drive 212 km, 3 hours 23 min

  • Plzeň Zoo
  • Cathedral of St. Bartholomew
  • Pilsner Urquell Brewery
  • Karlštejn Castle
  • More

On day 4 of your road trip in the Czech Republic, you’ll start and end your day in Prague, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Prague, there’s no need to rush. Experience Plzeň and Karlštejn to the fullest today with this curated day itinerary.

Karlštejn’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Plzeň behind. This drive usually takes around 1 hour 1 min. Karlštejn welcomes you with a multitude of unique vacation experiences.

Spend your afternoon discovering Dinopark Plzeň, a notable zoo known for its eye-catching features. Next, continue your sightseeing at Cathedral Of St. Bartholomew, an often recommended church.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Pilsner Urquell Brewery and uncover the details of this instagrammable brewery.

When you’re ready to jump back into the car and say goodbye to Plzeň, you’ll hit the road in the direction of Karlštejn. This drive usually takes around 1 hour 1 min.

Our first attraction recommendation in Karlštejn is Karlštejn Castle, a locally renowned castle that draws attention for its visually striking features.

When you’re done exploring for the day, you’ll return to Prague and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely dining experience at OSSEGG Praha - Pivovar & Restaurace, a popular restaurant in Prague. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Prague at U Fleků, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Havelská Koruna. It’s yet another ideal choice to enhance your time in Prague tonight.

Explore the vibrant nightlife at Bar Bohužel after your meal, a hub for lively evenings and memorable moments. Or, head to Hemingway Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Tečka is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass and celebrate another amazing day of your road trip in the Czech Republic!

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Day5

Day 5

  • Prague
  • Průhonice
  • Kutná Hora
  • Ústí nad Labem
  • More

Drive 236 km, 3 hours 29 min

  • Park Průhonice
  • St Barbara's Cathedral
  • Italian Court
  • Sedlec Ossuary
  • More

Experience an unparalleled adventure on day 5 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Průhonice and Kutná Hora. At the end of the day, you will retreat to the hotel of your choice in Ústí Nad Labem, where will spend 1 night.

When you’ve had your share of Průhonice, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Kutná Hora. Your travel time is around 1 hour 5 min.

Savor the day by heading to Park Průhonice, a beloved botanical garden that draws visitors from near and far.

When you’ve had your share of Průhonice, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Kutná Hora. Your travel time is around 1 hour 5 min.

When you're ready for some sights, head to St Barbara's Cathedral, an interesting church in Kutná Hora. Explore its culturally significant features at your own pace before you continue your journey to your next attraction, Italian Court. This beloved castle is a top recommendation in the area.

When you’re ready to explore more, Sedlec Ossuary is an excellent choice. Spend some time discovering what some claim to be the most photogenic church in the region.

At the end of the day, you will drive to Ústí Nad Labem, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Ústí Nad Labem. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delightful dinner at Restaurant Větruše, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Hotel a Restaurant Větruše? It's another excellent option with a diverse menu. Consider reserving a table at BLACKSHEEP BAR as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Ústí Nad Labem.

Round off your dining experience by visiting Hp Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Ústecká Pivotéka, a bar catering to every mood and preference. Pubs Bar Hamburg likewise offers a unique atmosphere, perfect for a memorable night out.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in the Czech Republic.

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Day6

Day 6

  • Ústí nad Labem
  • Mezná
  • Děčín
  • Vysoká Lípa
  • Špindlerův Mlýn
  • More

Drive 217 km, 4 hours 16 min

  • Kamenice Gorge
  • Bohemian Switzerland National Park
  • Dolský Mlýn
  • More

On day 6 of your road trip in the Czech Republic, your travel plans include 4 stops at the most scenic, wondrous, and interesting places in the region. Mezná, Děčín, Vysoká Lípa, and Harrachov are on today's agenda. In the evening, you’ll end up in Špindlerův Mlýn, where you will stay for 1 night.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Mezná may take around 45 min. Upon your arrival in Mezná, you’ll be greeted with the opportunity to do some sightseeing and exploring.

For a more meaningful self-guided tour of the village's best attractions, visit Kamenice Gorge, an intriguing canyon that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

Fasten your seatbelt and make your way to your next stop — Děčín, home to many well-known sights in the region. Keep in mind that your travel time from Mezná to Děčín may take around 12 min without traffic disruptions. Upon arrival in Děčín, we highly recommend checking out some of the top attractions.

One of our top recommendations for your sightseeing is České Švýcarsko National Park. Spend some time admiring the eye-catching features of the national park before you continue to your next stop.

Embrace the thrill of the open road as you wave goodbye to Děčín and set your GPS to Vysoká Lípa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 9 min. Upon reaching Vysoká Lípa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

When you're ready for some sights, head to Dolský Mlýn, an underrated historical landmark in Vysoká Lípa. Explore its awe-inspiring features at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Špindlerův Mlýn. Check in and relax before you head out to tour the village.

After a day of adventure, treat yourself to an exquisite dinner at one of Špindlerův Mlýn's best restaurants.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day7

Day 7

  • Špindlerův Mlýn
  • Janské Lázně
  • Prague
  • More

Drive 232 km, 3 hours 28 min

  • Špindlerův Mlýn Ski Resort
  • The Timber Trail, Krkonoše
  • More

Dive into day 7 of your remarkable road trip in the Czech Republic. Today you'll explore 3 destinations, including Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem. At the end of the day, you’ll unwind at one of the finest accommodations in Prague, where you'll spend 1 night.

To truly experience Špindlerův Mlýn, make sure to drop by Špindlerův Mlýn Ski Resort. This interesting ski resort is a must-visit for anyone seeking a unique vacation experience.

After soaking in Špindlerův Mlýn’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Janské Lázně. Expect your car journey to take a minimum of 35 min. When you arrive in Janské Lázně, it's time to take a break from the road.

Spend your afternoon discovering The Timber Trail, Krkonoše, a well-known canopy walk known for its picturesque features.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Prague. Prague offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at MAURIZIO restaurant & café, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Gate Restaurant, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of U Houmra, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Crazy Daisy, a well-loved spot among locals and tourists. Or, head to Puerto Rico Cafe & Cocktail Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Anonymous Bar, another top-rated place in the area.

Get a good night's sleep and look forward to another great day on the road in the Czech Republic!

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Day8

Day 8

  • Prague - Departure day
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  • Letná Park
  • More

Day 8 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Letná Park. This interesting park is a hotspot among locals.

Make the most of your final day in the Czech Republic by visiting Prague’s iconic markets and shopping establishments in the buzzing Palladium. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

Dine in style at Restaurace U Jindřišské věže, a top recommendation for dinner tonight. Or, for a change of pace, The Grand Mark Prague boasts a menu that's sure to impress.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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