6-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague traveling east to Český Krumlov and Brno

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Photo of old town pier architecture and Charles Bridge over Vltava river in Prague, Czech Republic.
Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
6-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague traveling east to Český Krumlov and Brno
6-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague traveling east to Český Krumlov and Brno
6-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague traveling east to Český Krumlov and Brno
6-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague traveling east to Český Krumlov and Brno
6-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague traveling east to Český Krumlov and Brno
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Explore the best of the Czech Republic on a remarkable 6-day road trip! Combine exploration with relaxation on a self-drive tour featuring Prague, Kutná Hora, Český Krumlov, Telč, Brno, Nové Dvory, Sloup, and Litomyšl.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 3 nights in Prague, 1 night in Český Krumlov, and 1 night in Brno. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Prague, Kutná Hora, Český Krumlov, Telč, Brno, Nové Dvory, Sloup, and Litomyšl, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay here for 2 nights and explore what to see in Prague, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Charles Bridge. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Prague. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at U Tellerů, a popular restaurant in Prague. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Prague at Restaurace U Bansethů, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Eska Restaurant and Bakery. It’s yet another ideal choice to enhance your time in Prague tonight.

Keep the evening going at Anonymous Shrink's Office, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bar No. 7 - Prague, which offers a similarly pleasant setting and great drinks. Another option is Kontakt Bar, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 6-day road trip in the Czech Republic!

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Day2

Day 2

  • Prague
  • Kutná Hora
  • More

Drive 178 km, 3 hours 5 min

  • Prague Castle
  • Powder Tower
  • Sedlec Ossuary
  • St Barbara's Cathedral
  • Malá Strana
  • More

On day 2 of your road trip in the Czech Republic, you’ll start and end your day in Prague, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Prague, there’s no need to rush. Experience Prague and Kutná Hora to the fullest today with this curated day itinerary.

Set aside time today to explore Malá Strana, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Make time for Prague Castle, a timeless castle that is worthwhile a visit in the city. Nearby, you’ll find Powder Tower, enchanting visitors with its culturally significant appeal.

It’s time to gear up for the next part of your road trip adventure. Upon your arrival in Kutná Hora, you’ll be greeted with the opportunity to do some sightseeing and exploring.

When you're ready for some sights, head to Sedlec Ossuary, a notable church in Kutná Hora. Explore its noteworthy features at your own pace before you continue your journey to your next attraction, St Barbara's Cathedral. This interesting church is a top recommendation in the area.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Prague.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Dine in style at Brasileiro Restaurant, a top recommendation for dinner tonight. Or, for a change of pace, Restaurant Meat Beer boasts a menu that's sure to impress. Also, be sure to check out Restaurace Století. Known as a local hotspot, it’s a great choice for tonight in Prague.

After enjoying a fulfilling meal, continue your evening at Bowla Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, The Saints offers a welcoming atmosphere for easing into the nightlife. Similarly, Beergeek Bar provides an excellent environment for a relaxed and enjoyable evening.

Savor another day of unforgettable experiences in the Czech Republic!

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Day3

Day 3

  • Prague
  • Český Krumlov
  • More

Drive 179 km, 2 hours 40 min

  • The Castle Garden
  • Český Krumlov Castle Tower
  • Lazebnický most
  • House of Mirrors
  • Egon Schiele Art Centrum
  • Moldavite Museum
  • More

On day 3 of your road trip in the Czech Republic, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Český Krumlov are on today's agenda. In the evening, you’ll end up in Český Krumlov, where you will stay for 1 night.

Embrace the thrill of the open road as you wave goodbye to Prague and set your GPS to Český Krumlov. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 14 min. Upon reaching Český Krumlov, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

For a more meaningful self-guided tour of the town's best attractions, visit The Castle Garden, an increasingly popular castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Český Krumlov Castle Tower and admire its romantic features.

When you’re ready, continue to Lazebnický Most, an often recommended bridge beloved by locals and tourists alike. Don't miss out on House Of Mirrors, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Egon Schiele Art Centrum, a standout place to see that you won’t regret spending some extra time discovering.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Český Krumlov. Český Krumlov offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Český Krumlov. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Raise your glass and celebrate another amazing day of your road trip in the Czech Republic!

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Day4

Day 4

  • Český Krumlov
  • Telč
  • Brno
  • More

Drive 246 km, 3 hours 59 min

  • Telč château
  • Villa Tugendhat
  • cathedral of St. Peter and Paul
  • Špilberk Castle
  • More

Experience an unparalleled adventure on day 4 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Telč and Brno. At the end of the day, you will retreat to the hotel of your choice in Brno, where will spend 1 night.

Throughout the day, make sure to take breaks to appreciate the surroundings.

Set your GPS to Telč and hit the road. Expect a journey of approximately 1 hour 47 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Telč beckons with new experiences!

Savor the day by heading to Telč Château, an intriguing castle that draws visitors from near and far.

Brno’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Telč behind. This drive usually takes around 1 hour 32 min. Brno welcomes you with a multitude of unique vacation experiences.

Spend your afternoon discovering Villa Tugendhat, a locally appreciated museum known for its breathtaking features. Next, continue your sightseeing at Cathedral Of St. Peter And Paul, an often recommended church.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Špilberk Castle and uncover the details of this historic castle.

At the end of the day, you will drive to Brno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Brno is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Brno.

Make sure to reserve a table at U Štíra, an iconic dining spot in Brno. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bistro Franz, a popular restaurant in Brno. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Noem Arch Restaurant, a hidden gem nestled in Brno. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue the enjoyment post-dinner at Bar Naproti, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Super Panda Circus offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Výčep Na Stojáka. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Head back to your accommodation in Brno and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day5

Day 5

  • Brno
  • Nové Dvory
  • Sloup
  • Litomyšl
  • Prague
  • More

Drive 294 km, 4 hours 36 min

  • Macocha Abyss
  • Punkva Caves
  • Sloupsko-šošůvské jeskyně
  • Monastery gardens
  • More

Your itinerary for day 5 of your road trip in the Czech Republic includes 3 stops and features some of the highlights of Nové Dvory, Sloup, and Litomyšl. At the end of the day, enjoy the comforts of a top-rated hotel in Prague, where you'll spend 1 night.

When you’ve had your share of Brno, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Nové Dvory. Your travel time is around 45 min.

One of our top recommendations for your sightseeing is Macocha Abyss. Spend some time admiring the idyllic features of the cave before you continue to your next stop. Then, head to Punkva Caves. This interesting cave system is a traveler-favorite in the village.

When you’ve had your share of Nové Dvory, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Sloup. Your travel time is around 22 min.

Savor the day by heading to Sloupsko-šošůvské Jeskyně, an often recommended cave system that draws visitors from near and far.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Litomyšl. This drive usually takes around 1 hour 9 min, without any stops or traffic disruptions.

Monastery Gardens In Litomyšl is a locally appreciated monastery we recommend visiting today. Discover its romantic features before continuing your self-guided tour.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at BeBop Bar, a top-rated dining destination in Prague. If you're in the mood to try something new, consider Café restaurant Palanda, another top spot with a mouthwatering menu. You might also want to secure a reservation at Restaurace Tiskárna. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Uhříněveský Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Boothill Bar offers an ideal atmosphere to enjoy the pleasures of the night. Manesova Bar And Books is also a great option that provides a perfect setting for a relaxing evening.

Raise your glass to another unforgettable day in the Czech Republic!

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Day6

Day 6

  • Prague - Departure day
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  • Old Town Square
  • More

Day 6 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Old Town Square, a symbolic public square before you head out.

For a shopping spree in Prague, we recommend the lively Na Příkopě Street. Here, you'll find a range of shops you can browse for some souvenir shopping.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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